Immune - Part 8

Immune

Immune 33: COVID-19 immunotypes

July 28, 2020
Tagged as: antibody, B cells, CD4 cells, CD8 cells, cell sorting, COVID-19, cytokines, FACS profiling, immune, immunology, immunotypes, lymphocytes, pandemic, SARS-CoV-2, T cells

Immune explains a study of 125 COVID-19 patients by deep immune profiling, which revealed three immunotypes associated with poor clinical prognosis or recovery.

Hosts: Vincent Racaniello and Cynthia Leifer

Guest: Brianne Barker

Click arrow to play
Download Immune 33 (50 MB .mp3, 84 min)
Subscribe (free): iTunes, Google Podcasts. RSS, email
Become a patron of Immune!

Links for this episode

CD8 cells defend against SARS-CoV (J Virol) 3:36
Deep immune profiling of COVID-19 patients (Science) 8:30
Letters read on Immune 33 1:11:05
Image credit
Time stamps by Jolene. Thanks!

Music by Steve Neal.
Immune logo image by Blausen Medical

Send your immunology questions and comments to [email protected]

Immune

Immune 32: Immunology of COVID-19, part four

June 5, 2020
Tagged as: antibody, COVID-19, cytokine signature, cytokine storm, immune, immunology, immunopathology, SARS-CoV-2, T cell

Immune continues a discussion of the immune response to infection with SARS-CoV-2, including inflammatory responses and disease, antibody and T-cell responses, and vaccines, and answers to listener questions.

Hosts: Vincent Racaniello, Stephanie Langel, and Cynthia Leifer

Guest: Brianne Barker

Click arrow to play
Download Immune 32 (54 MB .mp3, 91 min)
Subscribe (free): iTunes, Google Podcasts. RSS, email
Become a patron of Immune!

Links for this episode

Keep CoV off campus (NY Times) 10:17
Inflammatory cytokines predict COVID-19 death (medRxiv) 16:36
Imbalanced host response drives COVID-19 (Cell) 23:57
Convergent antibody responses in COVID-19 patients (bioRxiv) 32:53
Cross neutralization of SARS-CoV-2 by SARS-CoV mAb (Nature) 45:56
Human T-cell responses to SARS-CoV-2 (Cell) 36:12, 41:11
DNA vaccine protects rhesus macaques (Science) 47:02
Replicon RNA vaccine protects macaques (bioRxiv) 47:03
Letters read on Immune 32 1:04:37
Image credit
Time stamps by Jolene. Thanks!

Music by Steve Neal. Immune logo image by Blausen Medical

Send your immunology questions and comments to [email protected]

Immune

Immune 31: Immunology of COVID-19, part three

May 8, 2020
Tagged as: antibody, BCG, COVID-19, immune, immunology, OPV, SARS-CoV-2, vaccine

Immune continues a discussion of the immune response to infection with SARS-CoV-2, including vaccines and immunity, effects of BCG and OPV, immunity passports, and answers to listener questions.

Hosts: Vincent Racaniello, Stephanie Langel, and Cynthia Leifer

Guest: Brianne Barker

Click arrow to play
Download Immune 31 (55 MB .mp3, 90 min)
Subscribe (free): iTunes, Google Podcasts. RSS, email

Become a patron of Immune!

Links for this episode

How long will a vaccine really take? (NYTimes) 37:15
Humoral immunity in NYC COVID-19 patients (medRxiv) 43:13
D614G is just a SNP (TWiEVO 55) 32:54
Letters read on Immune 31 37:15
Image credit
Transcript of this episode (html, pdf)
Time stamps by Jolene. Thanks!

Music by Steve Neal. Immune logo image by Blausen Medical.

Send your immunology questions and comments to [email protected]

Immune

Immune 30: Immunology of COVID-19, part two

April 17, 2020
Tagged as: antibody, coagulation, coronavirus, COVID-19, cytokine storm, IL6, immune, immunology, SARS-CoV-2, steroids

Brianne Barker returns to continue a discussion of the immune response to infection with SARS-CoV-2, including use of steroid, coagulation in some patients, cytokine storm, and vaccines.

Hosts: Vincent Racaniello, Stephanie Langel, and Cynthia Leifer

Guest: Brianne Barker

Click arrow to play
Download Immune 30 (51 MB .mp3, 83 min)
Subscribe (free): iTunes, Google Podcasts. RSS, email

Become a patron of Immune!

Music by Steve Neal. Immune logo image by Blausen Medical.

Send your immunology questions and comments to [email protected]

Immune

Immune 29: Immunology of COVID-19

March 31, 2020
Tagged as: coronavirus, COVID-19, immune, immunology, immunopathology, pandemic, SARS-CoV-2, viral, virology, virus

Brianne Barker joins Immune to discuss the immune response to infection with SARS-CoV-2, including immune respones, pathogenesis, immunopathology and more.

Hosts: Vincent Racaniello, Stephanie Langel, and Cynthia Leifer

Guest: Brianne Barker

Click arrow to play
Download Immune 29 (53 MB .mp3, 87 min)
Subscribe (free): iTunes, Google Podcasts. RSS, email

Become a patron of Immune!

Links for this episode

ACE2 in oral mucosa (I J Oral Sci) 13:32
IL6 predictor of COVID-19 death (Int Care Med) 41:38
Protective immunity to SARS-CoV-2 in nonhuman primates (bioRxiv) 1:19:18
Antibody to SARS-CoV wanes (J Immunol)
Image credit
Time stamps by Jolene. Thanks!

Music by Steve Neal. Immune logo image by Blausen Medical.

Send your immunology questions and comments to [email protected]

Immune

Immune 28: Fish immunology

February 8, 2020
Tagged as: IgT, immune, immunology, microbiome, mucosal antibody, pathogen control, rainbow trout, teleost

Irene Salinas joins Immune to reveal the work of her laboratory on the evolution of mucosal immune responses in teleost fish, the oldest living bony vertebrates.

Hosts: Vincent Racaniello, Stephanie Langel, and Cynthia Leifer

Guest: Irene Salinas

Click arrow to play
Download Immune 28 (35 MB .mp3, 56 min)
Subscribe (free): iTunes, Google Podcasts. RSS, email

Become a patron of Immune!

Links for this episode

Evolution of mucosal Ig in rainbow trout (Sci Immunol) 19:12
Fish olfactory neurons mediate rapid immune response (PNAS) 39:32
Image credit
Time stamps by Jolene. Thanks!

Music by Steve Neal. Immune logo image by Blausen Medical.

Send your immunology questions and comments to [email protected]

Immune

Immune 27: Trained immunity

January 11, 2020
Tagged as: enhancer, H3K4Me1, immune, immune memory, immunology, innate immunity, LPS, methylation, NK cells, sepsis

Steph explains how sepsis induces protective immune memory in NK cells, via histone methylation of the interferon gamma enhancer.

Hosts: Vincent Racaniello, Stephanie Langel, and Cynthia Leifer

Click arrow to play
Download Immune 27 (57 MB .mp3, 94 min)
Subscribe (free): iTunes, Google Podcasts. RSS, email

Become a patron of Immune!

Links for this episode

H3K4me1 mark on memory-like NK cells (Cell Rep) 14:42
Letters read on Immune 27 1:08:37
Time stamps by Jolene. Thanks!

Weekly Science Picks 1:22:07

Steph – Rotavirus & polio vaccines should be separated (article, paper)
Cindy – Diversify Immunology
Vincent – No winter break from publish or perish

Music by Steve Neal. Immune logo image by Blausen Medical.

Send your immunology questions and comments to [email protected]

Immune

Immune 26: Measles erases immune memory

November 28, 2019
Tagged as: immune, immunology, immunosuppression, lymphocytes, measles virus, MMR vaccine, plasma cells, viral, VirScan, virus

Michael Mina joins the Immune team to explain his findings that measles diminishes pre-existing antibodies that protect against infection with other pathogens.

Hosts: Vincent Racaniello, Stephanie Langel, and Cynthia Leifer

Guest: Michael Mina

Click arrow to play
Download Immune 26 (59 MB .mp3, 98 min)
Subscribe (free): iTunes, Google Podcasts. RSS, email

Become a patron of Immune!

Links for this episode

Measles virus infection diminishes pre-existing antibodies (Science) 21:33
Public epitope #1 (TWiV 342) 33:12, 1:11:35
Incomplete reconstitution of B cell pools after measles (Sci Immunol) 1:14:15, 1:21:59
Time stamps by Jolene. Thanks!

Music by Steve Neal. Immune logo image by Blausen Medical.

Send your immunology questions and comments to [email protected]

Immune

Immune 25: Remembrance of antigen encounters past

November 1, 2019
Tagged as: antigen presentation, CD8+ T cells, glycolysis, high fiber diet, immune, immunology, microbiome, oxidative phosphorylation, short chain fatty acids, T cell memory, TCA cycle

The Immune team explains that short chain fatty acids produced by microbial fermentation of fiber rewire metabolism to enable the production of memory T cells.

Hosts: Vincent Racaniello, Stephanie Langel, and Cynthia Leifer

Click arrow to play
Download Immune 25 (50 MB .mp3, 82 min)
Subscribe (free): iTunes, Google Podcasts. RSS, email

Become a patron of Immune!

Links for this episode

CD8+ T cell memory needs microbiome derived fatty acids (Immune) 2:46
Image credit: Principles of Virology 4e
Time stamps by Jolene. Thanks!
Letters read on Immune 25 1:01:52

Weekly Science Picks 1:09:20

Stephanie – This Week in Neuroscience
Cindy – Graduate Abuse by Derek Lowe
Vincent – Funding ends for seeking new viruses

Music by Steve Neal. Immune logo image by Blausen Medical.

Send your immunology questions and comments to [email protected]

Immune

Immune 24: Unlucky IL-13

September 19, 2019
Tagged as: allergic responses, anaphylaxis, follicular T cell, IgE, immune, immunology, mast cells, T helper cell

The Immune team reveals a new type of T helper cell that drives the production of IgE, leading to allergic responses.

Hosts: Vincent Racaniello, Stephanie Langel, and Cynthia Leifer

Click arrow to play
Download Immune 24 (54 MB .mp3, 89 min)
Subscribe (free): iTunes, Google Podcasts. RSS, email

Become a patron of Immune!

Links for this episode

New type of T helper cell drives anaphylaxis (Science) 2:41, 32:50
Image credit
Time stamps by Jolene. Thanks!
Letters read on Immune 24 1:12:56

Weekly Science Picks 1:22:54

Cindy – Lasker Award 2019
Vincent – Eleanor’s Breakthrough video

Music by Steve Neal. Immune logo image by Blausen Medical.

Send your immunology questions and comments to [email protected]

« Previous 1 … 6 7 8 9 10 11 Next »

Immune 33: COVID-19 immunotypes

Links for this episode

Immune 32: Immunology of COVID-19, part four

Links for this episode

Immune 31: Immunology of COVID-19, part three

Links for this episode

Immune 30: Immunology of COVID-19, part two

Links for this episode

Immune 29: Immunology of COVID-19

Links for this episode

Immune 28: Fish immunology

Links for this episode

Immune 27: Trained immunity

Links for this episode

Weekly Science Picks 1:22:07

Immune 26: Measles erases immune memory

Links for this episode

Immune 25: Remembrance of antigen encounters past

Links for this episode

Weekly Science Picks 1:09:20

Immune 24: Unlucky IL-13

Links for this episode

Weekly Science Picks 1:22:54

Search

The Hosts of IMMUNE

Archived Posts

Contribute

Questions/Comments