Gabriel Victora joins Immune to review how high affinity antibodies are produced in the germinal centers of secondary lymphoid tissues.
Immune 49: I fell in love with worms with Keke Fairfax
- October 13, 2021
- Tagged as: B cells, egg antigen, helminth, IL-4, immune, immunology, immunometabolism, macrophage, schistosomiasis
Keke Fairfax joins Immune to discuss the work from her laboratory on understanding how maternal schistosomiasis impairs IL-4 production and B cell expansion in offspring, and modulation of macrophage immunometabolism by helminths.
Immune 45: Immune messages
- June 16, 2021
- Tagged as: antibody, B cells, complement, COVID-19, germinal centers, immune, immunology, macrophages, T cells, vaccine
On this episode of Immune, we answer listener questions about CAR-Macs, complement and COVID-19, sleep and the immune system, caving and the immune system, germinal centers, COVID-19 vaccines and much more.
Immune 42: Evolution of SARS-CoV-2 antibody immunity with Christian Gaebler
- February 13, 2021
- Tagged as: antibody, B cells, coronavirus, COVID-19, immune, immunology, memory B cells, pandemic, SARS-CoV-2
Christian joins Immune to discuss the humoral memory response in a cohort of 87 individuals 1.3 and 6.2 months after infection with SARS-CoV-2.
Immune 33: COVID-19 immunotypes
- July 28, 2020
- Tagged as: antibody, B cells, CD4 cells, CD8 cells, cell sorting, COVID-19, cytokines, FACS profiling, immune, immunology, immunotypes, lymphocytes, pandemic, SARS-CoV-2, T cells
Immune explains a study of 125 COVID-19 patients by deep immune profiling, which revealed three immunotypes associated with poor clinical prognosis or recovery.
Immune 21: Islets of Langelhans
- June 12, 2019
- Tagged as: autoimmunity, B cells, BCR, dual expressing lymphocytes, immune, immunology, public BCR, T cells, TCR, type I diabetes
Immune tackles the finding that patients with Type I diabetes have lymphocytes with both TCR and BCR that may drive the pathogenesis of the disease.
Immune 16: B is for Bursa
- January 19, 2019
- Tagged as: B cells, Bursa, gene knockout, herpesvirus, immune, immunology, Marek's disease, pathogenesis
The Immune team turns to chickens, which have been important in understanding the immune system, to show that infection of mature B cells is not required for the pathogenesis of Marek’s disease herpesvirus.