B cells | Immune

Immune discusses basophils as regulators of of lung inflammation over space and time, and neoself-antigens as the primary target for autoreactive T cells in human lupus. Hosts: Vincent Racaniello, Cindy Leifer, Steph Langel, and Brianne Barker…

Immune explores the immunological diversity in the upper airway, including memory B and T cells and germinal center B cells, and how chronic infection with Plasmodium parasites leads to development of B cell cancers. Hosts: Vincent…

Immune

Immune 73: Big macs

November 7, 2023
Tagged as: B cells, immune, immune cells, immunology, macrophage, T cell

Immune reveals the total mass (1.2kg), number (1.8 trillion), and distribution of immune cells in the human body, with macrophages contributing nearly 50% of the total cellular mass.

Immune

Immune 69: Lung cancer and retroviruses

June 15, 2023
Tagged as: antibody, B cells, cancer, endogenous retrovirus, env protein, ERV, germinal center, immune, immune checkpoint blockade, immunology, lung adenocarcinoma, tertiary lymphoid structure

Kevin joins Immune to discuss his work showing that antibodies against endogenous retroviruses promote immunotherapy of lung cancer.

Immune

Immune 68: Sins and blessings of immunity

May 18, 2023
Tagged as: antibody, B cells, coronavirus, COVID-19, immune, immune memory, immunological imprinting, immunology, original antigenic sin, pandemic, SARS-CoV-2

Immune discusses immunological imprinting, also called original antigenic sin, in the context of infection with SARS-CoV-2 and influenza virus.

Immune

Immune 66: COVID-19 immune memory – what you need to know

April 4, 2023
Tagged as: affinity maturation, antibody, B cells, coronavirus, COVID-19, hybrid immunity, immune, immune memory, immunology, natural immunity, pandemic, SARS-CoV-2, somatic hypermutation, T cell, vaccine, vaccine booster

Immune discusses the current understanding of immune memory to SARS-CoV-2 infection and COVID-19 vaccines, which supersedes that of any other acute infectious disease.

Immune

Immune 63: Immune, promptly

December 20, 2022
Tagged as: antibody, B cells, germinal center, immune, immunology, lymph node, T cells

Cindy, Steph, Brianne, and Vincent review some of their favorite immunology papers of 2022. Hosts: Vincent Racaniello, Cynthia Leifer, Steph Langel, and Brianne Barker Click arrow to playDownload Immune 63 (62 MB .mp3, 103 min)Subscribe (free): Apple Podcasts, Google Podcasts. RSS, emailBecome…

Immune

Immune 52: B cell boot camp with Gabriel Victora

January 29, 2022
Tagged as: antibodies, B cells, germinal center, immune, immunology, lymph node, lymphoid organ, somatic hypermutation

Gabriel Victora joins Immune to review how high affinity antibodies are produced in the germinal centers of secondary lymphoid tissues.

Immune

Immune 49: I fell in love with worms with Keke Fairfax

October 13, 2021
Tagged as: B cells, egg antigen, helminth, IL-4, immune, immunology, immunometabolism, macrophage, schistosomiasis

Keke Fairfax joins Immune to discuss the work from her laboratory on understanding how maternal schistosomiasis impairs IL-4 production and B cell expansion in offspring, and modulation of macrophage immunometabolism by helminths.

Immune

Immune 45: Immune messages

June 16, 2021
Tagged as: antibody, B cells, complement, COVID-19, germinal centers, immune, immunology, macrophages, T cells, vaccine

On this episode of Immune, we answer listener questions about CAR-Macs, complement and COVID-19, sleep and the immune system, caving and the immune system, germinal centers, COVID-19 vaccines and much more.

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Tag: B cells

Immune 87: When the immune system misbehaves

Immune 85: Immune trade-offs

Immune 73: Big macs

Immune 69: Lung cancer and retroviruses

Immune 68: Sins and blessings of immunity

Immune 66: COVID-19 immune memory – what you need to know

Immune 63: Immune, promptly

Immune 52: B cell boot camp with Gabriel Victora

Immune 49: I fell in love with worms with Keke Fairfax

Immune 45: Immune messages

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