ImmuneImmuneImmuneImmune

Tag: immune memory

  • Immune

Immune 68: Sins and blessings of immunity

  • May 18, 2023
  • Tagged as: antibody, B cells, coronavirus, COVID-19, immune, immune memory, immunological imprinting, immunology, original antigenic sin, pandemic, SARS-CoV-2

Immune discusses immunological imprinting, also called original antigenic sin, in the context of infection with SARS-CoV-2 and influenza virus.

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  • Immune

Immune 66: COVID-19 immune memory – what you need to know

  • April 4, 2023
  • Tagged as: affinity maturation, antibody, B cells, coronavirus, COVID-19, hybrid immunity, immune, immune memory, immunology, natural immunity, pandemic, SARS-CoV-2, somatic hypermutation, T cell, vaccine, vaccine booster

Immune discusses the current understanding of immune memory to SARS-CoV-2 infection and COVID-19 vaccines, which supersedes that of any other acute infectious disease.

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  • Immune

Immune 36: Aberrant immunity in COVID-19

  • October 21, 2020
  • Tagged as: antibody, coronavirus, COVID-19, germinal center, herd immunity, humoral immunity, immune, immune memory, immunology, pandemic, SARS-CoV-2, somatic hypermutation

Immune describes the striking loss of germinal centers in lymph nodes and spleen in patients with severe COVID-19, providing an explanation for short-lived humoral immunity and limited somatic hypermutation of antibodies to SARS-CoV-2.

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  • Immune

Immune 27: Trained immunity

  • January 11, 2020
  • Tagged as: enhancer, H3K4Me1, immune, immune memory, immunology, innate immunity, LPS, methylation, NK cells, sepsis

Steph explains how sepsis induces protective immune memory in NK cells, via histone methylation of the interferon gamma enhancer.

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