Immune discusses the current understanding of immune memory to SARS-CoV-2 infection and COVID-19 vaccines, which supersedes that of any other acute infectious disease.
Cindy, Steph, Brianne, and Vincent do a rapid review of 11 immunology papers, including a wiring diagram for the immune system, group A streptococcus vaccines, systems immunology prediction of vaccines, class switch towards IgG4 after SARS-CoV-2 mRNA vaccination, very bad B cells, monoclonal antibody to two streptococcal M protein epitopes, transcriptional atlas of response to 13 vaccines, impact of SARS-CoV-2 exposure history on T cell and IgG response, neutrophilic inflammation predisposes to RSV infection, commensals avoiding recognition, and continuous germinal center invasion contributes to diversity of immune response.
Immune 45: Immune messages
- June 16, 2021
- Tagged as: antibody, B cells, complement, COVID-19, germinal centers, immune, immunology, macrophages, T cells, vaccine
On this episode of Immune, we answer listener questions about CAR-Macs, complement and COVID-19, sleep and the immune system, caving and the immune system, germinal centers, COVID-19 vaccines and much more.
Immune 40: COVID-19 nuances
- December 30, 2020
- Tagged as: antibody, coronavirus, COVID-19, immune, immunity, immunology, pandemic, SARS-CoV-2, T cell, T cell exhaustion, vaccine
Immune reminisces about a year in COVID-19 immunology, Steph’s receiving the Pfizer vaccine, and answers to listener questions about a challenge study with common cold CoVs, T cell exhaustion, how CD4 T cells control infections, and more.
Sallie joins Immune to discuss her career, emphasizing the importance of a good mentor and the ability to pivot, and her research, which has focused on mother to child transmission of infectious diseases including HIV/AIDS, CMV, and more recently, COVID-19/SARS-CoV-2.
Immune 31: Immunology of COVID-19, part three
- May 8, 2020
- Tagged as: antibody, BCG, COVID-19, immune, immunology, OPV, SARS-CoV-2, vaccine
Immune continues a discussion of the immune response to infection with SARS-CoV-2, including vaccines and immunity, effects of BCG and OPV, immunity passports, and answers to listener questions.
Immune 22: Engineering B cells
- July 31, 2019
- Tagged as: allelic exclusion, antibody, B cell, CRISPR/Cas, heavy chain, immune, immunology, light chain, vaccine
Immune reveals an alternative to a protective vaccine, engineered B cells that produce antiviral antibodies.
The Immune team discusses immunization of pregnant mice to protect offspring from neonatal herpes simplex virus disease.