ImmuneImmuneImmuneImmune

Tag: B cell

  • Immune

Immune 22: Engineering B cells

  • July 31, 2019
  • Tagged as: allelic exclusion, antibody, B cell, CRISPR/Cas, heavy chain, immune, immunology, light chain, vaccine

Immune reveals an alternative to a protective vaccine, engineered B cells that produce antiviral antibodies.

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  • Immune

Immune 6: Potent antiviral antibodies without somatic mutation

  • March 16, 2018
  • Tagged as: antibody, B cell, epitope, F protein, IgG, IgM, immune, immune response, immunology, lymph node, respiratory syncytial virus, somatic hypermutation, V(D)J recombination, vaccine enhanced disease

The Immune hosts explain how antibody molecules mature, then discuss the finding in infants of potent neutralizing antibodies against respiratory syncytial virus without somatic hypermutation.

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  • Immune

Immune 4: Putting the immunotherapy CAR T before the cancer

  • January 23, 2018
  • Tagged as: B cell, cancer immunotherapy, CAR T cell, checkpoint inhibitor, chimeric antigen receptor, CTLA4, immune, immunology, immunotherapy, oncology, PD-1, T cell, Tisagenlecleucel

The immu-knowledge-ists deconstruct the holy grail of oncologists, cancer immunotherapy, and the exciting development of CAR T cells and how they work.

3 Replies
  • Immune

Immune 2: Lymphocytes after dark

  • November 25, 2017
  • Tagged as: 24 hour clock, adaptive immunity, B cell, circadian, clock gene, immune, immunology, lymph, lymph node, lymphocyte, T cell

Cindy, Steph, and Vincent reveal that lymphocyte trafficking through lymph nodes and lymph is circadian – it is dependent on the time of day.

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