ImmuneImmuneImmuneImmune

Tag: T cell

  • Immune

Immune 51: Teenage NINJA mice with Nikhil Joshi

  • December 22, 2021
  • Tagged as: central tolerance, immune, immunology, LCMV, neoantigen, NINJA mouse, T cell, thymus

Nikhil Joshi joins Immune to discuss the creation of NINJA mice that synthesize neoantigens to enable the study of endogenous antigen-specific naïve T cell responses in disease and infection.

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  • Immune

Immune 40: COVID-19 nuances

  • December 30, 2020
  • Tagged as: antibody, coronavirus, COVID-19, immune, immunity, immunology, pandemic, SARS-CoV-2, T cell, T cell exhaustion, vaccine

Immune reminisces about a year in COVID-19 immunology, Steph’s receiving the Pfizer vaccine, and answers to listener questions about a challenge study with common cold CoVs, T cell exhaustion, how CD4 T cells control infections, and more.

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  • Immune

Immune 37: Black in Immuno

  • November 16, 2020
  • Tagged as: black in immune, Black voices in immunology, dendritic cell, diversity, immune, immunology, macrophage, NK cell, systemic racism, T cell

Alexis, Joel, Elaine, Justine, and Evonne join Immune to discuss their careers, their research, and a platform created by a collective of Black immunologists and allies aimed at amplifying, celebrating and supporting Black voices in immunology.

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  • Immune

Immune 34: Coronavirus cross-reacting T cells

  • August 25, 2020
  • Tagged as: CD4 T cell, coronavirus, COVID-19, epitope, MHC molecule, pandemic, peptide, SARS-CoV-2, T cell, T cell epitope, T cell receptor, viral, virology, virus, viruses

Immune explains a study demonstrating T cells that react with SARS-CoV-2 epitopes in individuals who have never been infected with the virus, implying cross-reactivity with common cold coronaviruses.

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  • Immune

Immune 32: Immunology of COVID-19, part four

  • June 5, 2020
  • Tagged as: antibody, COVID-19, cytokine signature, cytokine storm, immune, immunology, immunopathology, SARS-CoV-2, T cell

Immune continues a discussion of the immune response to infection with SARS-CoV-2, including inflammatory responses and disease, antibody and T-cell responses, and vaccines, and answers to listener questions.

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  • Immune

Immune 14: Braking bad

  • November 14, 2018
  • Tagged as: cancer immunotherapy, CTLA-4, immune, immune checkpoint inhibitor, immunology, immunotherapy, James Allison Tasuku Honjo, Nobel Prize, PD-1, PDL-1, T cell

The Immune team explains the science behind the 2018 Nobel Prizes awarded to Allison and Honjo: checkpoint immunotherapy.

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  • Immune

Immune 4: Putting the immunotherapy CAR T before the cancer

  • January 23, 2018
  • Tagged as: B cell, cancer immunotherapy, CAR T cell, checkpoint inhibitor, chimeric antigen receptor, CTLA4, immune, immunology, immunotherapy, oncology, PD-1, T cell, Tisagenlecleucel

The immu-knowledge-ists deconstruct the holy grail of oncologists, cancer immunotherapy, and the exciting development of CAR T cells and how they work.

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  • Immune

Immune 2: Lymphocytes after dark

  • November 25, 2017
  • Tagged as: 24 hour clock, adaptive immunity, B cell, circadian, clock gene, immune, immunology, lymph, lymph node, lymphocyte, T cell

Cindy, Steph, and Vincent reveal that lymphocyte trafficking through lymph nodes and lymph is circadian – it is dependent on the time of day.

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