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Immune

Immune 34: Coronavirus cross-reacting T cells

August 25, 2020
Tagged as: CD4 T cell, coronavirus, COVID-19, epitope, MHC molecule, pandemic, peptide, SARS-CoV-2, T cell, T cell epitope, T cell receptor, viral, virology, virus, viruses

Immune explains a study demonstrating T cells that react with SARS-CoV-2 epitopes in individuals who have never been infected with the virus, implying cross-reactivity with common cold coronaviruses.

Immune

Immune 32: Immunology of COVID-19, part four

June 5, 2020
Tagged as: antibody, COVID-19, cytokine signature, cytokine storm, immune, immunology, immunopathology, SARS-CoV-2, T cell

Immune continues a discussion of the immune response to infection with SARS-CoV-2, including inflammatory responses and disease, antibody and T-cell responses, and vaccines, and answers to listener questions.

Immune

Immune 14: Braking bad

November 14, 2018
Tagged as: cancer immunotherapy, CTLA-4, immune, immune checkpoint inhibitor, immunology, immunotherapy, James Allison Tasuku Honjo, Nobel Prize, PD-1, PDL-1, T cell

The Immune team explains the science behind the 2018 Nobel Prizes awarded to Allison and Honjo: checkpoint immunotherapy.

Immune

Immune 4: Putting the immunotherapy CAR T before the cancer

January 23, 2018
Tagged as: B cell, cancer immunotherapy, CAR T cell, checkpoint inhibitor, chimeric antigen receptor, CTLA4, immune, immunology, immunotherapy, oncology, PD-1, T cell, Tisagenlecleucel

The immu-knowledge-ists deconstruct the holy grail of oncologists, cancer immunotherapy, and the exciting development of CAR T cells and how they work.

Immune

Immune 2: Lymphocytes after dark

November 25, 2017
Tagged as: 24 hour clock, adaptive immunity, B cell, circadian, clock gene, immune, immunology, lymph, lymph node, lymphocyte, T cell

Cindy, Steph, and Vincent reveal that lymphocyte trafficking through lymph nodes and lymph is circadian – it is dependent on the time of day.

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Tag: T cell

Immune 34: Coronavirus cross-reacting T cells

Immune 32: Immunology of COVID-19, part four

Immune 14: Braking bad

Immune 4: Putting the immunotherapy CAR T before the cancer

Immune 2: Lymphocytes after dark

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