The immune professors discuss neutrophil extracellular traps, and how IgA-virus immune complexes potentiate this process through Fc receptors on neutrophils.
Immune 45: Immune messages
- June 16, 2021
- Tagged as: antibody, B cells, complement, COVID-19, germinal centers, immune, immunology, macrophages, T cells, vaccine
On this episode of Immune, we answer listener questions about CAR-Macs, complement and COVID-19, sleep and the immune system, caving and the immune system, germinal centers, COVID-19 vaccines and much more.
Immune 44: Got IgA on the brain
- May 17, 2021
- Tagged as: antibody, EAE, IgA, immune, immunology, immunosuppression, multiple sclerosis, neuroinflammation, plasma cell
On this episode of Immune, IgA-producing plasma cells mobilized from the gut play an unexpected role in suppressing neuroinflammation.
Immune 42: Evolution of SARS-CoV-2 antibody immunity with Christian Gaebler
- February 13, 2021
- Tagged as: antibody, B cells, coronavirus, COVID-19, immune, immunology, memory B cells, pandemic, SARS-CoV-2
Christian joins Immune to discuss the humoral memory response in a cohort of 87 individuals 1.3 and 6.2 months after infection with SARS-CoV-2.
Immune 40: COVID-19 nuances
- December 30, 2020
- Tagged as: antibody, coronavirus, COVID-19, immune, immunity, immunology, pandemic, SARS-CoV-2, T cell, T cell exhaustion, vaccine
Immune reminisces about a year in COVID-19 immunology, Steph’s receiving the Pfizer vaccine, and answers to listener questions about a challenge study with common cold CoVs, T cell exhaustion, how CD4 T cells control infections, and more.
Immune describes the striking loss of germinal centers in lymph nodes and spleen in patients with severe COVID-19, providing an explanation for short-lived humoral immunity and limited somatic hypermutation of antibodies to SARS-CoV-2.
Immune 33: COVID-19 immunotypes
- July 28, 2020
- Tagged as: antibody, B cells, CD4 cells, CD8 cells, cell sorting, COVID-19, cytokines, FACS profiling, immune, immunology, immunotypes, lymphocytes, pandemic, SARS-CoV-2, T cells
Immune explains a study of 125 COVID-19 patients by deep immune profiling, which revealed three immunotypes associated with poor clinical prognosis or recovery.
Immune 32: Immunology of COVID-19, part four
- June 5, 2020
- Tagged as: antibody, COVID-19, cytokine signature, cytokine storm, immune, immunology, immunopathology, SARS-CoV-2, T cell
Immune continues a discussion of the immune response to infection with SARS-CoV-2, including inflammatory responses and disease, antibody and T-cell responses, and vaccines, and answers to listener questions.
Immune 31: Immunology of COVID-19, part three
- May 8, 2020
- Tagged as: antibody, BCG, COVID-19, immune, immunology, OPV, SARS-CoV-2, vaccine
Immune continues a discussion of the immune response to infection with SARS-CoV-2, including vaccines and immunity, effects of BCG and OPV, immunity passports, and answers to listener questions.
Immune 30: Immunology of COVID-19, part two
- April 17, 2020
- Tagged as: antibody, coagulation, coronavirus, COVID-19, cytokine storm, IL6, immune, immunology, SARS-CoV-2, steroids
Brianne Barker returns to continue a discussion of the immune response to infection with SARS-CoV-2, including use of steroid, coagulation in some patients, cytokine storm, and vaccines.