Jon joins Immune to discuss the research of his laboratory on understanding how the innate immune system recognizes and responds to pathogens, and his hypothesis that infection infidelities drive innate immunity.
Cindy, Steph, Brianne, and Vincent do a rapid review of 11 immunology papers, including a wiring diagram for the immune system, group A streptococcus vaccines, systems immunology prediction of vaccines, class switch towards IgG4 after SARS-CoV-2 mRNA vaccination, very bad B cells, monoclonal antibody to two streptococcal M protein epitopes, transcriptional atlas of response to 13 vaccines, impact of SARS-CoV-2 exposure history on T cell and IgG response, neutrophilic inflammation predisposes to RSV infection, commensals avoiding recognition, and continuous germinal center invasion contributes to diversity of immune response.
Immune 63: Immune, promptly
- December 20, 2022
- Tagged as: antibody, B cells, germinal center, immune, immunology, lymph node, T cells
Cindy, Steph, Brianne, and Vincent review some of their favorite immunology papers of 2022. Hosts: Vincent Racaniello, Cynthia Leifer, Steph Langel, and Brianne Barker Click arrow to playDownload Immune 63 (62 MB .mp3, 103 min)Subscribe (free): Apple Podcasts, Google Podcasts. RSS, emailBecome…
Immune 62: Every cell is an immune cell with De’Broski Herbert
- December 2, 2022
- Tagged as: helminth, immune, immunology, mucosal immunity, neuroimmunology, parasite, type 2 immunity
De’Broski joins immune to reveal his remarkable career path and the research of his laboratory on neuroimmunology and the immune response to parasite infections.
Immune 61: Training immune cells with Julia Bohannon and Musa Mhlanga
- November 8, 2022
- Tagged as: immune, immunology, trained innate immunity
From SLB22 on the Island of Hawai’i, Julia and Musa join Immune to reveal their remarkable career paths, and their research on understanding trained innate immunity.
Sumali and Phil join Immune to discuss their approaches to immunology education.
Immune 59: Forks in the road: Th17 cells with Mandy McGeachy
- August 19, 2022
- Tagged as: immune, immunology, rheumatoid arthritis, T helper cells, Th17 cells
At Cornell University in Ithaca, NY, Mandy joins Immune to discuss her career and her research on understanding how Th17 cells develop and are influenced to be ‘good’ or ‘bad’ in their function.
Immune 58: Gut B cells awry in ulcerative colitis
- August 3, 2022
- Tagged as: IgA, IgG, immune, immunology, monocyte, plasmablast, single cell RNA sequencing, ulcerative colitis
Immune explains a study of three cohorts of patients with ulcerative colitis which finds major perturbations within the mucosal B cell compartment, highlighting a potential role for these cells in disease pathogenesis.
Immune reviews data showing that in mice, skin bacteria activate keratinocytes to stimulate hair follicle regeneration and wound healing.
Immune 56: Flip flops on the thymic beach with Al Singer
- June 1, 2022
- Tagged as: CD4, CD8, flip flop mice, immune, immunology, lineage fate determination, MHC I, MHC II, T cell, T cell receptor
Al Singer joins immune to discuss mice that have their T cell immune system reversed, revealing the molecular basis for T cell lineage fate determination in the thymus.