Immune discusses two stories of immune cells eating other cells: microglia engulfing brain neurons to shape cortical development and behavior, and mast cells trapping neutrophils to increase their functional and metabolic fitness.
Immune reviews the local and systemic responses after human SARS-CoV-2 challenge infection, and how bat antibodies display elevated antigen binding strength and diversity at higher temperatures that are characteristic of flight.
Immune presents three stories: intranasal neomycin and antiviral immunity, sexual dimorphism in skin immunity, and maternal diet changes infant microbes that alter gut DC responses and respiratory health.
Immune explains how antibody-mediated depletion of myeloid-hematopoietic stem cells in aged mice restores characteristic features of a more youthful immune system, including increasing common lymphocyte progenitors, naive T cells and B cells, while decreasing age-related markers of immune decline.
Immune discusses responses in a COVID hypervaccinated individual, synthetically glycosylated antigens for the antigen-specific suppression of established immune responses, gut bacteria–derived serotonin promotes immune tolerance in early life, and mucosal and systemic immune correlates of viral control after SARS-CoV-2 infection challenge.
Immune 40: COVID-19 nuances
- December 30, 2020
- Tagged as: antibody, coronavirus, COVID-19, immune, immunity, immunology, pandemic, SARS-CoV-2, T cell, T cell exhaustion, vaccine
Immune reminisces about a year in COVID-19 immunology, Steph’s receiving the Pfizer vaccine, and answers to listener questions about a challenge study with common cold CoVs, T cell exhaustion, how CD4 T cells control infections, and more.
The Immune team explores the variable lymphocyte receptors of jawless vertebrates, a system of immunity that parallels the structurally unrelated antibodies of jawed vertebrates.
