Immune discusses immunological imprinting, also called original antigenic sin, in the context of infection with SARS-CoV-2 and influenza virus.
Immune 67: Can T cells live forever?
- May 3, 2023
- Tagged as: immune, immunology, longevity, memory T cell, senescence, supernumerary cell division, T cells, vaccination
Immune explains the results of a study which show that in mice, functional T cells respond to vaccination for over 10 years and 51 successive immunizations, exhibiting supernumerary cell division and longevity.
Immune discusses the current understanding of immune memory to SARS-CoV-2 infection and COVID-19 vaccines, which supersedes that of any other acute infectious disease.
Jon joins Immune to discuss the research of his laboratory on understanding how the innate immune system recognizes and responds to pathogens, and his hypothesis that infection infidelities drive innate immunity.
Cindy, Steph, Brianne, and Vincent do a rapid review of 11 immunology papers, including a wiring diagram for the immune system, group A streptococcus vaccines, systems immunology prediction of vaccines, class switch towards IgG4 after SARS-CoV-2 mRNA vaccination, very bad B cells, monoclonal antibody to two streptococcal M protein epitopes, transcriptional atlas of response to 13 vaccines, impact of SARS-CoV-2 exposure history on T cell and IgG response, neutrophilic inflammation predisposes to RSV infection, commensals avoiding recognition, and continuous germinal center invasion contributes to diversity of immune response.
Immune 63: Immune, promptly
- December 20, 2022
- Tagged as: antibody, B cells, germinal center, immune, immunology, lymph node, T cells
Cindy, Steph, Brianne, and Vincent review some of their favorite immunology papers of 2022. Hosts: Vincent Racaniello, Cynthia Leifer, Steph Langel, and Brianne Barker Click arrow to playDownload Immune 63 (62 MB .mp3, 103 min)Subscribe (free): Apple Podcasts, Google Podcasts. RSS, emailBecome…
Immune 62: Every cell is an immune cell with De’Broski Herbert
- December 2, 2022
- Tagged as: helminth, immune, immunology, mucosal immunity, neuroimmunology, parasite, type 2 immunity
De’Broski joins immune to reveal his remarkable career path and the research of his laboratory on neuroimmunology and the immune response to parasite infections.
Immune 61: Training immune cells with Julia Bohannon and Musa Mhlanga
- November 8, 2022
- Tagged as: immune, immunology, trained innate immunity
From SLB22 on the Island of Hawai’i, Julia and Musa join Immune to reveal their remarkable career paths, and their research on understanding trained innate immunity.
Sumali and Phil join Immune to discuss their approaches to immunology education.
Immune 59: Forks in the road: Th17 cells with Mandy McGeachy
- August 19, 2022
- Tagged as: immune, immunology, rheumatoid arthritis, T helper cells, Th17 cells
At Cornell University in Ithaca, NY, Mandy joins Immune to discuss her career and her research on understanding how Th17 cells develop and are influenced to be ‘good’ or ‘bad’ in their function.