From the American Association of Immunologists 2024 conference in Chicago, Cindy and Steph meet up with Jane Buckner to talk about her career, and the research of her laboratory on mechanisms by which regulation of the adaptive immune response fails or is overcome in the setting of human autoimmunity.
Immune reveals a CD8+ regulatory subset of T cell subset that suppress pathogenic T cells and are active in autoimmune diseases and infectious diseases including COVID-19.
Immune tackles the finding that patients with Type I diabetes have lymphocytes with both TCR and BCR that may drive the pathogenesis of the disease.