TWiN answers listener questions on sex in neuroscience studies, rotating memories in the brain, odorant receptors in the brain, and neutrophils that promote neuron survival.

Hosts: Vincent Racaniello, Jason Shepherd, and Timothy Cheung

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Download TWiN 025  (75 MB .mp3, 63 min)
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Music is by Ronald Jenkees

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Ioana and Robert join TWiN to discuss their work demonstrating that rodents acquire maternal behavior by social transmission from an experienced mother to a virgin female how to care for a litter via endogenous oxytocin.

Hosts: Vincent Racaniello and Timothy Cheung

Guests: Ioana Carcea and Robert Froemke

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Download TWiN 024  (44 MB .mp3, 73 min)
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Music is by Ronald Jenkees

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Bruce Carter joins TWiN to discuss the peripheral nervous system: the development of nerves that convey sensory information like touch from the tips of your toes to the brain, and Schwann cells, which are necessary for ensuring that those sensory signals are sustained as they travel long distances to the brain.

Hosts: Vincent Racaniello, Timothy Cheung, and Vivianne Morrison

Guest: Bruce Carter

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Download TWiN 023  (41 MB .mp3, 68 min)
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Music is by Ronald Jenkees

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TWiN explains how anti-DNA antibodies present in lupus patients bind to GluN2A-containing NMDA receptors, act as positive allosteric modulators, and impair spatial memory.

Hosts: Vincent Racaniello, Ori Lieberman, Jason Shepherd, Timothy Cheung, and Vivianne Morrison

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Download TWiN 022  (41 MB .mp3, 68 min)
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TWiN explores a study of hallucination-like perception in mice which supports the idea that hallucinations arise as faulty perceptual inferences due to elevated dopamine in the striatum.

Hosts: Vincent Racaniello, Ori Lieberman, and Timothy Cheung

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Download TWiN 021  (53 MB .mp3, 88 min)
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While perceptual constancy requires the brain to maintain a stable representation of sensory input, TWiN explores a study showing that odor-evoked responses in the olfactory cortex drift over periods of days to weeks.

Hosts: Vincent Racaniello, Jason Shepherd, Timothy Cheung, and Vivianne Morrison

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Download TWiN 019  (43 MB .mp3, 71 min)
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On this episode, Vivianne gives a primer on glial cells, with the goal of thinking about the central nervous system holistically and appreciating the different cell types that contribute to its function.

Hosts: Vincent Racaniello, Jason Shepherd, Timothy Cheung, and Vivianne Morrison

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Download TWiN 019  (43 MB .mp3, 71 min)
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Music is by Ronald Jenkees

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Mauro Costa-Mattioli joins TWiN to discuss how his laboratory dissects the contribution of host genetics and the microbiome in complex neurodevelopment disorders such as autism spectrum disorders.

Hosts: Vincent Racaniello, Ori Lieberman, Jason Shepherd, Timothy Cheung, and Vivianne Morrison

Guest: Mauro Costa-Mattioli

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Download TWiN 018  (43 MB .mp3, 71 min)
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Music is by Ronald Jenkees

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Michael Nitabach joins TWiN to discuss the finding that the nematode C. elegans, which do not have eyes, can discriminate between colors to guide foraging decisions and move them away from harmful bacteria that produce a blue-pigment toxin.

Hosts: Vincent Racaniello, Ori Lieberman, Jason Shepherd, Timothy Cheung, and Vivianne Morrison

Guest: Michael Nitabach

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Download TWiN 017  (49 MB .mp3, 82 min)
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Stefano joins TWiN to discuss his work on understanding genomic decoding of neuronal depolarization by stimulus-specific transcriptional regulators.

Hosts: Ori Lieberman, Jason Shepherd, and Timothy Cheung

Guest: Stefano Brigidi

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Download TWiN 016  (41 MB .mp3, 68 min)
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Music is by Ronald Jenkees

Send your neuroscience questions and comments to twin@microbe.tv