TWiN 8: Replacing lost neurons

TWiN explains how neurological disease in mice can be repaired by using CRISPR/Cas to knock down levels of a single cell protein, which converts astrocytes to neurons.

Hosts: Ori Lieberman, Erin Calipari, Jason Shepherd and Vincent Racaniello

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Intro music is by Ronald Jenkees

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TWiN 7: Stress, the good, bad and beautiful

The TWiN team reveals how the nervous system controls hair graying in mice subjected to stress, and adaptive immune responses.

Hosts: Ori Lieberman, Jason Shepherd,  Erin Calipari and Vincent Racaniello

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Intro music is by Ronald Jenkees

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TWiN 6: Neural control of sexual behavior

Nirao Shah joins TWiN to discuss the work of his laboratory on how our brains generate social interactions that differ between the sexes.

Hosts: Ori Lieberman, Andres Bendesky, and Jason Shepherd

Guest: Nirao Shah

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Intro music is by Ronald Jenkees.

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TWiN 5: Anosmia and COVID-19

Olfactory epithelium

Bob Datta joins TWiN to reveal the findings of his laboratory on expression of SARS-CoV-2 entry genes in the olfactory epithelium and the implications for anosmia associated with COVID-19.

Hosts: Ori Lieberman, Andres Bendesky, Jason Shepherd, Erin Calipari and Vincent Racaniello

Guest: Bob Datta

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Intro music is by Ronald Jenkees.

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TWiN 4: It’s a trap!

Jason visits the TWiN studio to explain Arc Capsid Bearing Any RNAs (ACBARs), virus-like capsids that transfer genetic information between neurons.

Hosts: Andres Bendesky, Jason Shepherd, and Vincent Racaniello

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Download TWiN 004 (42 MB .mp3, 68 min)
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Intro music is by Ronald Jenkees.

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TWiN 3: Gambling on dopamine

Erin and the TWiN team explain how dopamine neurons encode reward probability and uncertainty, and their roles in attention-based learning and risk-taking such as gambling and addiction.

Hosts: Ori Lieberman, Erin Calipari,Jason Shepherd, and Vincent Racaniello

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Intro music is by Ronald Jenkees.

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TWiN 2: Cells that fire together wire together

The TWiN team explain the basic principles of synaptic transmission, and review a classic paper demonstrating that recycling endosomes are important for modifying synaptic strength, which is involved in information storage and processing.

Hosts: Ori Lieberman, Andres Bendesky,Jason Shepherd, and Vincent Racaniello

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Intro music is by Ronald Jenkees.

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TWiN 1: The ultimate challenge

The synaptics launch the first episode of TWiN by revealing their training, research interests, and goals for the podcast.

Hosts: Ori Lieberman, Erin Calipari, Jason Shepherd, and Vincent Racaniello

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Intro music is by Ronald Jenkees.

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