TWiN 59: AI co-scientist

Tim explains AI co-scientist, a tool released by Google, which it hopes to help scientists generate hypotheses and research proposals, and to accelerate the speed of scientific and biomedical discoveries.

Hosts: Vincent Racaniello, Tim Cheung, and Vivianne Morrison

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Download TWiN 059 (54 MB .mp3, 75 min)
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Music is by Ronald Jenkees

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TWiN 58: Tongue-dragging rescue behavior

TWiN explains a study showing that when a mouse is confronted with an unconscious conspecific, it engages in behavior including tongue-dragging to resuscitate the animal via a tongue-brain connection.

Hosts: Vincent Racaniello, Tim Cheung, and Vivianne Morrison

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Download TWiN 058 (54 MB .mp3, 74 min)
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Music is by Ronald Jenkees

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TWiN 57: Repetitive injury, herpes, and Alzheimer’s

TWiN discusses a study showing that repetitive injury reactivates HSV-1 in a human brain tissue model and induces phenotypes associated with Alzheimer’s disease.

Hosts: Vincent Racaniello and Tim Cheung

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Download TWiN 057 (29 MB .mp3, 40 min)
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Music is by Ronald Jenkees

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TWiN 56: Astrocytes help neurons remember

TWiN explains a study showing that while groups of neurons, form the basis for memory, astrocytes are key components of the adaptive reponse to learning experiences, and regulate the flow of information during circuit plasticity and memory recall.

Hosts: Vincent Racaniello, Jason Shepherd, and Tim Cheung

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Download TWiN 056 (44 MB .mp3, 61 min)
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Music is by Ronald Jenkees

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TWiN 55: A brain circuit for day/night balance

TWiN explains the identification of a brain circuit and periodic branch-specific neurotransmitter deployment that regulates organismal adaptation to photoperiod change.

Hosts: Vincent Racaniello, Jason Shepherd, and Tim Cheung

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Download TWiN 055 (42 MB .mp3, 69 min)
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Music is by Ronald Jenkees

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TWiN 54: How pregnancy transforms the brain

TWiN explores how pregnancy leads to modifications in brain structure and function that may prepare the mother for parenting.

Hosts: Vincent Racaniello, Jason Shepherd, and Vivianne Morrison

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Download TWiN 054 (39 MB .mp3, 65 min)
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Music is by Ronald Jenkees

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TWiN 53: Slowing time by cooling the brain

Joseph Paton and Felipe Rodrigues join TWiN to explain how they used temperature manipulation to alter the speed of neuronal dynamics in the dorsal striatum of rats, a manipulation that selectively slowed down or sped up time perception, illuminating the mechanisms of time-based decisions.

Hosts: Vincent Racaniello, Jason Shepherd, Timothy Cheung, and Vivianne Morrison

Guest: Joseph J. Paton and Felipe Rodrigues

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Download TWiN 053 (50 MB .mp3, 70 min)
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Music is by Ronald Jenkees

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TWiN 52: Probiotic improves social behavior in children with ASD

Mauro Costa-Mattioli returns to TWiN to discuss the results of a placebo controlled, double blind clinical trial of a probiotic which improved social behavior but not autism severity in children with ASD.

Hosts: Jason Shepherd, Timothy Cheung, and Vivianne Morrison

Guest: Mauro Costa-Mattioli

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Download TWiN 052 (47 MB .mp3, 66 min)
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Music is by Ronald Jenkees

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TWiN 51: Sensory processing dysfunction in autism spectrum disorders

TWiN reviews altered somatosensory reactivity, which is frequently observed among individuals with autism spectrum disorders (ASD), and in mouse models the developmental timing of aberrant touch processing can predict the manifestation of ASD-associated behaviors in mouse models. 

Hosts: Vincent Racaniello, Jason Shepherd, Timothy Cheung, and Vivianne Morrison

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Download TWiN 051 (51 MB .mp3, 71 min)
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Music is by Ronald Jenkees

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TWiN 50: Neurological sequelae after COVID-19

TWiN reviews experiments which show that SARS-CoV-2 triggers the up-regulation of synaptic components and perturbs local electrical field potential in cerebral organoids, organotypic culture of human brain explants and post-mortem brain samples from individuals with COVID-19. 

Hosts: Vincent Racaniello, Jason Shepherd, Timothy Cheung, and Vivianne Morrison

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Download TWiN 050 (46 MB .mp3, 64 min)
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Music is by Ronald Jenkees

Send your neuroscience questions and comments to twin@microbe.tv

About the Hosts


Jason Shepherd, Ph.D.


Vivianne Morrison, Ph.D.


Tim Cheung, Ph.D.


Vincent Racaniello, Ph.D.


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Please note that content in MicrobeTV podcasts should not be construed as medical advice.