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Tag: microglia

  • This Week in Neuroscience

TWiN 37: Microglia at the crossroads

  • January 23, 2023
  • Tagged as: microglia, neurobiology, neuroinflammation, neuroscience, nomenclature

TWiN reviews the field of microgial research, which has advanced in recent decades but is constrained by nomenclature that is necessary but often implies specific functions. Hosts: Vincent Racaniello, Jason Shepherd, Timothy Cheung, and Vivianne…

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  • This Week in Neuroscience

TWiN 34: Microglia vital after spinal cord injury

  • September 30, 2022
  • Tagged as: astrocyte, macrophage, microglia, neurobiology, neurology, neuroscience, RNA sequencing, spinal cord injury

TWiN explains how central nervous system resident macrophages known as microglia coordinate cellular interactions during spinal cord repair in mice.

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  • This Week in Neuroscience

TWiN 19: Glia 101

  • June 21, 2021
  • Tagged as: astrocytes, central nervous system, connective tissue, ependymal cells, glial cells, macroglia, microglia, neurology, neuroscience, oligodendrocytes, peripheral immune cells, vascular and perivascular cells

On this episode, Vivianne gives a primer on glial cells, with the goal of thinking about the central nervous system holistically and appreciating the different cell types that contribute to its function.

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  • This Week in Neuroscience

TWiN 13: mRNAs for long-term memory

  • December 16, 2020
  • Tagged as: astrocyte, contextual fear memory, engrams, inflammation, learning, long-term memory, membrane fusion, memory, memory consolidation, microglia, neuron, neuroscience

Ori, Jason, Erin, and Vincent dissect a study that utilizes single-cell RNA sequencing to reveal the genes that underlie remote memory storage in the medial prefrontal cortex of the mouse.

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  • This Week in Neuroscience

TWiN 10: Remodeling synapses with a cytokine

  • September 29, 2020
  • Tagged as: cytokine, hippocampus, IL-33, microglia, neurology, neuron, neuronal circuit, neuroscience, spine plasticity, synapse remodeling

TWiN explains how a cytokine produced by neurons activates microglia which modify the extracellular matrix and remodel synapses, leading to memory consolidation.

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