The TWiVerati follow up on the Ebola virus outbreak, virulence of Ebola-Makona, and reveal how a parasitoid is revealed to hyperparasitoids, and binding of influenza virus to a calcium ion channel to mediate influenza virus entry.
Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler
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Download TWiV 495 (67 MB .mp3, 111 min)
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Links for this episode
- ASM Microbe 2018 3:20
- Support Viruses & Cells Gordon Conference
- Faculty positions at Icahn School of Medicine 2:36
- International dsRNA Virus Symposium 9:07
- Tracing Ebola virus contacts (CIDRAP) 27:13
- WHO FAQ Ebola virus vaccine (WHO) 28:40
- Nipah virus outbreak (CIDRAP) 35:36
- Revealing parasitoid to hyperparasitoid (PNAS) 42:03
- Hyperparasitoid video (YouTube) 59:17
- Calcium channel and influenza virus entry (Cell Host Microbe) 1:03:10
- Letters read on TWiV 495 11:34, 1:20:04
Weekly Science Picks 1:33:41
Alan – National Cryptologic Museum
Rich – Science is mostly about staring
Dickson – New Zealand gloworms
Kathy – Opening of Smithsonian Outbreak; conference advice General ASV
Vincent – ICTV online
Intro music is by Ronald Jenkees.
Send your virology questions and comments to [email protected]
Vincent, Kathy, and Alan review the ongoing outbreak of Ebola virus in the Democratic Republic of the Congo, and the finding that mutations identified in the 2015 West African epidemic do not alter pathogenesis in animals.
The TWiVerati discuss the FDA Advisory Committee deliberation on the anti-poxvirus drug tecovirimat, and immune cells in gut-associated lymphoid tissue as the major target during acute murine norovirus infection.
The Masters of the TWiXome review the development of sensitive, portable, and field-based viral diagnostics using the CRISPR-Cas system.
The TWiVome deconstructs the evolutionary history of RNA viruses, and immune promotion of murine norovirus pathogenesis by replication in intestinal tuft cells.
From the TWiV team, human cowpox infection possibly acquired from a pet cat, and a new giant mimivirus of green algae with genes encoding enzymes of fermentation.
At the Medical College of Wisconsin, Vincent talks with current and former members of the Department of Microbiology and Immunology about their work and their careers.
Sean Whelan returns to TWiV to speak with Vincent about using haploid cell lines to identify genes encoding cell receptors for viruses, including Ebolavirus, Lassa virus, and more.
