TWiEVO 53: Virus evolution by land and by sea and by CoV, part II
- Nels and Vincent continue their discussion of SARS-CoV-2 from an evolutionary viewpoint, focusing on what the genome sequences tell us about the virus. post
TWiV 597: A lot of immunology and some COVID-19 with Jon Yewdell
- Immunologist Jon Yewdell joins Vincent and Rich to discuss immune responses in the context of infection with SARS-CoV-2. post
TWiM 214: Masterful subversion
- Vincent, Elio and Michael reveal the ASM COVID-19 summit, and how Salmonella injects a protein into the cell to drive suppression of the immune response. post
TWiV 596: COVID-19 - an ounce of prevention
- TWiV covers trials of hydroxychloroquine and convalescent plasma therapy for COVID-19, and answers listener questions on blood tests for antibodies, cross-protection among coronaviruses, acquiring infection from food or the gas pump, face masks containing copper, and much more. post
Immune 29: Immunology of COVID-19
- Brianne Barker joins Immune to discuss the immune response to infection with SARS-CoV-2, including immune respones, pathogenesis, immunopathology and more. post
TWiV 595: Coronavirus update - Daniel Griffin MD in the parking lot
- Daniel Griffin MD joins TWiV from a hospital parking lot to provide updates on COVID-19 diagnostics, clinical picture, and therapeutics, and then the TWiV team continues coverage of the coronavirus pandemic caused by SARS-CoV-2. post
TWiV Special: Conversation with a COVID-19 patient, Ian Lipkin
- Ian Lipkin joins Vincent to talk about his experience as a COVID-19 patient, and issues surrounding the disease and SARS-CoV-2 including limiting transmission, antivirals, vaccines, and much more. post
TWiM 213: Fugitive emissions
- Vincent, Elio and Michael discuss the stability of human coronaviruses on surfaces and in aerosols, and peptidoglycan production by a mosaic consisting of a bacterium within a bacterium within an insect. post
TWiP 181: Daniel's drive-through
- Dickson, Daniel and Vincent solve the case of the Two Volunteers With Watery Diarrhea, discuss diagnosis of SARS-CoV-2 in the New York area, and reveal an approach to preventing honeybee colony collapse by imbuing their gut bacteria with the ability to produce antiviral and antiparasite double-stranded RNAs. post
TWiEVO 52: Virus evolution by land and by sea and by CoV
- Nels and Vincent examine SARS-CoV-2 from an evolutionary viewpoint, examining what the spike glycoprotein sequence informs us about the origin of the virus. post
Immune 28: Fish immunology
- Irene Salinas joins Immune to reveal the work of her laboratory on the evolution of mucosal immune responses in teleost fish, the oldest living bony vertebrates. post
TWiP 180: A spleen palaver
- The TWiP professors solve the case of the Ugandan Child with Splenomegaly, and reveal that mutations in the P. falciparum genome that confer artemisinin resistance interfere with endocytic uptake of hemoglobin. post
TWiM 212: A coronavirus outbreak and IRF4 deficiency in Whipple's disease
- The TWiM team reviews the coronavirus outbreak that began in Wuhan, China, and the finding that an IRF deficiency underlies Whipple’s disease. post
TWiEVO 51: The starting point paradox
- Nels and Vincent dive deep into evolution and consider how new proteins emerged billions of years ago, when there were no other proteins to serve as starting material. post
TWiP 179: Verminous visitors
- The TWiP DVD solve the case of the Child Who Passed Worms, and discuss a non-human primate model for severe malarial anemia. post
Immune 27: Trained immunity
- Steph explains how sepsis induces protective immune memory in NK cells, via histone methylation of the interferon gamma enhancer. post
TWiM 211: Bacteria, colon cancer, and fire blight
- The Fellowship of the TWiM reveal that colorectal cancer-associated microbiota are associated with higher numbers of methylated genes in colonic mucosa, and identification of metabolites needed by the fire blight disease bacterium for virulence in apples. post
TWiN 4: It's a trap!
- Jason visits the TWiN studio to explain Arc Capsid Bearing Any RNAs (ACBARs), virus-like capsids that transfer genetic information between neurons. post
TWiEVO 50: I'm dreaming of a Y chromosome
- Nels and Vincent discuss signatures of sex chromosome evolution revealed by assembly of a young vertebrate Y chromosome from 3-spined stickleback fish. post
TWiN 3: Gambling on dopamine
- Erin and the TWiN team explain how dopamine neurons encode reward probability and uncertainty, and their roles in attention-based learning and risk-taking such as gambling and addiction. post
TWiP 178: The shadowlands of medicine
- The Knights of the TWiP solve the case of the Man Who Lost Weight, and discuss a Plasmodium protein kinase that is a malarial drug target. post
Immune 26: Measles erases immune memory
- Michael Mina joins the Immune team to explain his findings that measles diminishes pre-existing antibodies that protect against infection with other pathogens. post
TWiN 2: Cells that fire together wire together
- The TWiN team explain the basic principles of synaptic transmission, and review a classic paper demonstrating that recycling endosomes are important for modifying synaptic strength, which is involved in information storage and processing. post
TWiN 1: The ultimate challenge
- The synaptics launch the first episode of TWiN by revealing their training, research interests, and goals for the podcast. post
Urban Agriculture 29: Gotham Greens
- Dickson travels to indoor farm Gotham Greens in Brooklyn, New York to speak with Co-founder and CEO Viraj Puri. post
Buckyball viruses
- How to build several types of virus particles using the small, powerful magnets called Buckyballs. post
Urban Agriculture 28: The Vertical Farm Institute
- Daniel joins Dickson and Vincent to talk about the Vertical Farm Institute, which provides advice and planning on the design and construction of indoor farms. post
Urban Agriculture 27: The Next Big Things
- Dickson provides an updates on progress towards establishing long-term, sustainable, local, safe food systems based on indoor farming. post
Zika in the guys
- In this episode of Virus Watch, we explore the finding that Zika virus infects the testis of mice, causing damage to the organ, reduced sperm production, and less fertility. The important question: does the same happen in humans? post
Urban Agriculture 26: Green Sense Farms
- Dickson and Vincent speak with Robert Colangelo, founding farmer and CEO of Green Sense Farms, the world's largest commercial indoor vertical farm. post
Cancer Killing Viruses
- Guest host Lynda Coughlan reviews how oncolytic viruses, which specifically kill tumor cells, are designed and how they work. post
Polio in Nigeria
- Polio returns to Nigeria after two years - but it turns out it had never gone away. post