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    • TWiV 915: Mouse mouth to mouse mom
      TWiV 915: Mouse mouth to mouse momJuly 3, 2022TWiV discusses the recent decision by an FDA advisory committee to update COVID vaccines for the fall, the monkeypox virus outbreak, and the finding that enteric viruses infect the salivary glands and are transmitted through saliva. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Kathy Spindler, and Brianne Barker. Click arrow to playDownload TWiV 915 (70 MB .mp3, 117 min)Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Postdoctoral position in the Kielian Laboratory (pdf)COVID vaccine update for fall (WaPo)Don’t rush to change COVID vaccines (STAT)Materials from 28 June FDA advisory meeting (FDA)Monkeypox cases US and Global (CDC)Enteric viruses transmit via saliva (Nature)Letters read on TWiV 915Timestamps by Jolene. Thanks! Weekly Picks Dickson – Jazz big bands #2: Maynard Ferguson: Signature song: Theme From Rocky: Signature album: Color Him WildBrianne – Origami antibody and virusKathy – Turbines resistant to high windsRich – Obi-Wan Kenobi (TV Series)Vincent – The next epidemic may be here. The US isn’t ready for it. Listener Picks David: DALL E 2Douglas – Jazz Online Intro music is by Ronald JenkeesSend your virology questions and comments to twiv@microbe.tv... Read more...
    • TWiEVO 79: When the immune system is away, SARS-CoV-2 will play
      TWiEVO 79: When the immune system is away, SARS-CoV-2 will playJuly 2, 2022Nels and Vincent discuss an analysis of the drivers of evolution of SARS-CoV-2 during chronic infections, indicating that a tradeoff exists between antibody evasion and fitness. Hosts: Nels Elde and Vincent Racaniello Click arrow to playDownload TWiEVO 79  (59 MB .mp3, 98 min)Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiEVO Links for this episode SARS-CoV-2 evolution during chronic infection (Nat Med)Letters read on TWiEVO 79Time stamps by Jolene. Thanks! Science Picks Nels – NASA scientists say images from the Webb telescope nearly brought them to tearsVincent – FDA: Don’t rush a move to change the Covid-19 vaccine composition Music on TWiEVO is performed by Trampled by TurtlesSend your evolution questions and comments to twievo@microbe.tv... Read more...
    • TWiV 914: COVID-19 clinical update #121 with Dr. Daniel Griffin
      TWiV 914: COVID-19 clinical update #121 with Dr. Daniel GriffinJuly 2, 2022In COVID-19 clinical update #121, Dr. Griffin discusses age as a risk factor for severe disease, updated vaccine boosters for the fall, pediatric infection and antibody seroprevalence in Arkansas over the first year of the COVID-19 pandemic, all-cause maternal mortality in the United States before and during the pandemic, and the effect of 2-week interruption in methotrexate treatment and how it impacts vaccine immunity. Click arrow to playDownload TWiV 914 (22MB .mp3, 37 min)Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Age as a risk factor for severe disease (NY Times)Omicron boosters for the fall (NPR)Pediatric infection and antibody seroprevalence in Arkansas (PIDS)All-cause US maternal mortality during pandemic (JAMA)Effect of 2-week interruption in methotrexate treatment (The Lancet)PAXLOVID patient eligibility screening checklist (FDA)Remdesivir fact sheet for providers (Veklury) Bebtelovimab fact sheet for providers (FDA)PAXLOVID drug interaction checker (IDSA)Contribute to FIMRC fundraiser at PWB 35:42Dr. Griffin’s treatment guide (pdf)Letters read on TWiV 914Timestamps by Jolene. Thanks! Intro music is by Ronald JenkeesSend your questions for Dr. Griffin to daniel@microbe.tv... Read more...
    • TWiP 207: Accidental host with Claire Panosian, MD
      TWiP 207: Accidental host with Claire Panosian, MDJuly 1, 2022Claire joins the TWiP team to discuss her training and experience as an infectious disease physician, and her transition to science communication, then we solve the case of the Honduran Male with Seizures. Hosts: Vincent Racaniello, Dickson Despommier, Daniel Griffin, and Christina Naula Guest: Claire Panosian Click arrow to playDownload TWiP #207 (56 MB .mp3, 93 minutes) Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Claire’s websiteClaire’s videos (Vimeo)Letters read on TWiP 207 Become a patron of TWiP Case Study for TWiP 207 Woman in 20s, spent time in Kenya 6 months prior, vomited up a worm. 0.5 cm in length. Sent to lab. Was moving. Earlier that day she went out with friends to sushi place, ate fish. Developed horrible abdominal pain, then vomited.  Send your case diagnosis, questions and comments to twip@microbe.tv Music by Ronald Jenkees... Read more...
    • Immune 57: Bacteria, the new cure for wounds?
      Immune 57: Bacteria, the new cure for wounds?June 30, 2022Immune reviews data showing that in mice, skin bacteria activate keratinocytes to stimulate hair follicle regeneration and wound healing. Hosts: Vincent Racaniello, Cynthia Leifer, Steph Langel, and Brianne Barker Click arrow to playDownload Immune 57 (42 MB .mp3, 69 min)Subscribe (free): Apple Podcasts, Google Podcasts. RSS, emailBecome a patron of Immune! Links for this episode Bacteria induce skin regeneration via IL-1beta (Cell Host Microbe)Time stamps by Jolene. Thanks! Music by Steve Neal. Immune logo image by Blausen MedicalSend your immunology questions and comments to immune@microbe.tv... Read more...
    • TWiN 31: HIV-1 co-receptor shapes window for memory linking
      TWiN 31: HIV-1 co-receptor shapes window for memory linkingJune 29, 2022TWiN explains the observation that in mice, the HIV-1 co-receptor CCR5 closes the temporal window for linking different memories. Hosts: Vincent Racaniello, Jason Shepherd, Timothy Cheung, and Vivianne Morrison Click arrow to playDownload TWiN 031 (43 MB .mp3, 72 min)Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode CCR5 and memory linking (Nature)Timestamps by Jolene. Thanks! Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv... Read more...
    • Infectious Disease Puscast #5
      Infectious Disease Puscast #5June 29, 2022On episode #5 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the previous two weeks, 6/8/22 – 6/22/22. Host: Daniel Griffin Click arrow to playDownload Puscast 005 (19 MB .mp3, 32 min)Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Effect of testing for respiratory pathogens on antibiotic use of children (JAMA)Outbreak of hepatitis in children (Intensive Care Medicine)Leptospirosis in retirees in rural areas (IDSA)Comparing Ceftolozane/Tazobactam to standard of care in the management of neutropenia and fever in patients with hematological malignancies (IDSA)Development of an electronic algorithm to target outpatient antimicrobial stewardship efforts for acute bronchitis and pharyngitis (IDSA)Compassionate-use of phages in twenty patients with drug-resistant mycobacterial disease (CID)Microbial Cell-Free DNA Identifies the Causative Pathogen in Infective Endocarditis (CID)The source of the Black Death in fourteenth-century central Eurasia (Nature)Noninvasive Testing and Surrogate Markers in Invasive Fungal Diseases (OFID)WHO guideline for the treatment of visceral leishmaniasis in HIV co-infected patients (WHO)Broad antimicrobial resistance in a case of relapsing babesiosis successfully treated with tafenoquine (CID)Human Filariasis in Travelers and Migrants (CID) Therapeutic hyperthermia is associated with improved survival in afebrile critically ill patients with sepsis (Critical Care Medicine)Does a school-based intervention to engage parents change opportunity for handwashing with soap at home? (PLOS NTD)Infectious diseases compensation in the USA (The Lancet) Intro music is by Ronald Jenkees... Read more...
    • TWiV 913: Twinkle twinkle little SARS
      TWiV 913: Twinkle twinkle little SARSJune 26, 2022TWiV explains the meaning of vaccine-derived poliovirus found in London sewage, risk of long COVID after infections with Delta or Omicron variants of SARS-CoV-2, and enhancers of innate immune signaling as broad-spectrum antivirals. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler. Click arrow to playDownload TWiV 913 (70 MB .mp3, 117 min)Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Poliovirus in UK sewage (ProMedMail and Science) 6:15, 13:39Poliovirus eradication effort (Science) 16:25Long COVID after Delta and Omicron (Lancet) 22:07How common is long COVID? (Nature) 22:04, 32:34Immune enhancers as antivirals (Cell Chem Biol) 37:03Letters read on TWiV 913 1:13:54Timestamps by Jolene. Thanks! Weekly Picks 1:32:46 Dickson – Count Basie: April in ParisKathy – Bird aerodynamics & inertia: lay article, video, NatureRich – NASA Gateway (Thanks Ellis)Alan – Polio Eradication in NigeriaVincent – The Tyranny of Merit by Michael J. Sandel Intro music is by Ronald JenkeesSend your virology questions and comments to twiv@microbe.tv... Read more...
    • TWiM 267: The honey badger of pathogens with Heran Darwin
      TWiM 267: The honey badger of pathogens with Heran DarwinJune 25, 2022From ASM Microbe 2022 in Washington, DC, Heran joins TWiM to discuss her career and her work on the agent of tuberculosis, Mycobacterium tuberculosis. Hosts: Vincent Racaniello, Michael Schmidt, and Michele Swanson Guest: Heran Darwin Right click to download TWiM #267 (35 MB .mp3, 47 minutes) Subscribe to TWiM (free) on Apple Podcasts, Google Podcasts, Stitcher, Android, RSS, or by email. Become a Patron of TWiM! Links for this episode: Honey badger of pathogens (EMBO Rep)Pup-proteasome system (PNAS)Cytokinin signaling in M. tuberculosis (mBio)Bandwagoning (EMBO Rep) Music used on TWiM is composed and performed by Ronald Jenkees and used with permission. Send your microbiology questions and comments to twim@microbe.tv... Read more...
    • TWiV 912: COVID-19 clinical update #120 with Dr. Daniel Griffin
      TWiV 912: COVID-19 clinical update #120 with Dr. Daniel GriffinJune 25, 2022In COVID-19 clinical update #120, Dr. Griffin discusses outcomes of SARS-CoV-2 reinfection, CDC recommendation for vaccines in young children, neurodevelopment outcomes in infants of mothers testing positive for COVID during pregnancy, efficacy of monoclonal antibodies and antivirals in hamsters, rebound phenomenon after PAXLOVID in high-risk persons, hospitalization for infection after PAXLOVID treatment, and risk of long COVID with different variants. Click arrow to playDownload TWiV 912 (27 MB .mp3, 45 min)Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Reinfection outcomes (Research Square) 2:40CDC recommends vaccine for young children (CDC) 12:31Neurodevelopment outcomes in infants post-infection (JAMA) 14:46Efficacy of monoclonal antibodies/antivirals in hamsters (Nature) 20:01PAXLOVID patient eligibility screening checklist (FDA)Remdesivir fact sheet for providers (Veklury) Bebtelovimab fact sheet for providers (FDA)PAXLOVID drug interaction checker Rebound phenomenon after PAXLOVID in high-risk persons (IDSA) 23:51Hospitalization for infection after PAXLOVID treatment (CDC) 25:38Risk of post acute infection with different variants (the Lancet) 28:22Contribute to FIMRC fundraiser at PWB 35:42Dr. Griffin’s treatment guide (pdf)Letters read on TWiV 912 36:34Timestamps by Jolene. Thanks! Intro music is by Ronald JenkeesSend your questions for Dr. Griffin to daniel@microbe.tv... Read more...
    • TWiV 911: Antibody can get vaccinated now
      TWiV 911: Antibody can get vaccinated nowJune 19, 2022TWiV provides an update on hepatitis of unknown etiology in children, an experimental nanoparticle vaccine for Epstein-Barr virus, and minimal impact of bamlanivimab therapy on antiviral antibodies induced by vaccination. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker Click arrow to playDownload TWiV 911 (76 MB .mp3, 127 min)Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Hepatitis of unknown etiology (MMWR) 6:49Clinical recognition of monkeypox (CDC) 47:49Epstein-Barr virus nanoparticle vaccine (Cell Rep Med) 14:22Minimal impact of mAb therapy on COVID vaccine induced antibodies (Sci Trans Med) 48:51Letters read on TWiV 911 1:05:43Timestamps by Jolene. Thanks! Weekly Picks 1:41:20 Brianne – A Frog So Small, It Could Not FrogKathy – A Grand Night In: The Story of AardmanRich – ArchiveVincent – Bandwagoning by Heran Darwin Intro music is by Ronald JenkeesSend your virology questions and comments to twiv@microbe.tv... Read more...
    • TWiV 910: COVID-19 clinical update #119 with Dr. Daniel Griffin
      TWiV 910: COVID-19 clinical update #119 with Dr. Daniel GriffinJune 18, 2022In COVID-19 clinical update #119, Dr. Griffin reviews tixagevimab for infection prevention, ivermectin for outpatient infection treatment, symptom rebound after PAXLOVID treatment, bamlanivimab minimally impacting immune response to vaccination, in-hospital mortality among infection patients, residual viral antigen in patients following infection, usage of Casirvimab/Imdevimab and Remdesivir in infected patients with depleted B-cells, and rheumatic symptoms following infection. Click arrow to playDownload TWiV 910 (29 MB .mp3, 48 min)Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Tixagevimab-Cilgavimab for infection prevention (NEJM) 15:33Ivermectin for outpatient infection treatment (medRxiv) 20:10Symptom rebound after PAXLOVID treatment (IDSA) 27:17, 28:11Bamlanivimab minimally impacts immune response to vaccination (Sci Transl Med) 30:50In-hospital morality among infected patients (IDSA) 33:33Casirvimab/Imdevimab & Remdesivir for infected B-cell depleted patients (IDSA) 35:18PAXLOVID patient eligibility screening checklist (FDA) Remdesivir fact sheet for providers (Veklury) Bebtelovimab fact sheet for providers (FDA)Residual viral antigen in patients post infection (IDSA) 36:07Rheumatic symptoms following infection (IDSA) 38:39Contribute to FIMRC fundraiser at PWB 40:08Dr. Griffin’s treatment guide (pdf)Letters read on TWiV 910 40:59Timestamps by Jolene. Thanks! Intro music is by Ronald JenkeesSend your questions for Dr. Griffin to daniel@microbe.tv... Read more...

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