Latest Podcasts
TWiV 1022: Clinical update with Dr. Daniel Griffin
TWiV 1022: Clinical update with Dr. Daniel GriffinJuly 8, 2023In his weekly clinical update, Dr. Griffin discusses autochthonous leprosy in the United States, a systematic review to identify novel clinical characteristics of Mpox virus infection and therapeutic and preventive strategies to combat the virus, two-year duration of immunity of inactivated poliovirus vaccine, evaluation of novel oral polio vaccine type 2 SIA impact in a large outbreak of circulating vaccine-derived poliovirus in Nigeria, performance of rapid antigen tests to detect symptomatic and asymptomatic SARS-CoV-2 Infection, effectiveness of the COVID-19 bivalent vaccine, oral Nirmatrelvir and Ritonavir for COVID-19 in vaccinated, non-hospitalized adults ages 18-50 years, genome-wide association study of long COVID, vaccination ameliorates cellular inflammatory responses in SARS-CoV-2 breakthrough infections, and high incidence of autonomic dysfunction and postural orthostatic tachycardia syndrome in patients with long-COVID. [...] read more...
BTN #7: Vaccine misinformation with RFK, Jr.
BTN #7: Vaccine misinformation with RFK, Jr.July 3, 2023Paul discusses Joe Rogan’s vaccine misinformation-filled podcast with RFK Jr and his call for a debate with scientists on the topic. [...] read more...
TWiV 1021: Nextstrain with Trevor Bedford
TWiV 1021: Nextstrain with Trevor BedfordJuly 2, 2023From ASV 2023 in Athens, Georgia, Vincent, Kathy and Brianne speak with Trevord Bedford about his career, the development of Nextstrain.org for real-time tracking of pathogen evolution, and evolution of SARS-CoV-2 from January 2020 through Omicron. [...] read more...
TWiV 1020: Clinical update with Dr. Daniel Griffin
TWiV 1020: Clinical update with Dr. Daniel GriffinJuly 1, 2023In his weekly clinical update, Dr. Griffin discusses guidance on measles during the summer travel season, the Infectious Diseases Society of America guidelines on the diagnosis of COVID-19: antigen testing, SARS-CoV-2 variants and age-dependent infection rates among household and nonhousehold contacts, effect of COVID-19 vaccination on household transmission of SARS-COV-2 in the Omicron era, incidence of myopericarditis after mRNA COVID-19 vaccination, intrinsic and effective severity of COVID-19 cases infected with the ancestral strain and Omicron BA.2 variant in Hong Kong, safety, immunogenicity and protection of heterologous boost with an aerosolized Ad5-nCoV after two-dose inactivated COVID-19 vaccines in adults, awake prone positioning for non-intubated patients with COVID-19-related acute hypoxic respiratory failure, melatonin effects on sleep quality of COVID-19 patients, female reproductive health impacts of Long COVID and associated illnesses including ME/CFS, POTS, and connective tissue disorders, and incident autoimmune diseases in association with SARS-CoV-2 infection. [...] read more...
TWiP 218: Malaria parasite evades mosquito
TWiP 218: Malaria parasite evades mosquitoJune 29, 2023TWiP solves two cases this week, the Man with Issues after COVID-19, and the Man with Left Arm Weakness, then describe how the malaria parasite evades mosquito immunity by glutaminyl cyclase–mediated posttranslational protein modification. [...] read more...
Infectious Disease Puscast #31
Infectious Disease Puscast #31June 28, 2023On episode #31 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 6/8 – 6/20/23. [...] read more...
TWiV 1019: Eddie Holmes on SARS-CoV-2 origins
TWiV 1019: Eddie Holmes on SARS-CoV-2 originsJune 25, 2023From ASM Microbe in Houston, Texas, Vincent speaks with Eddie Holmes about the evidence that SARS-CoV-2 spilled over into humans in the Huanan Market in Wuhan, absence of evidence for other origins, and his work on the virosphere. [...] read more...
TWiV 1018: Clinical update with Dr. Daniel Griffin
TWiV 1018: Clinical update with Dr. Daniel GriffinJune 24, 2023In his weekly clinical update, Dr. Griffin discusses the CDC vaccine advisory group recommending the newly approved RSV vaccines, association of culturable-virus detection and household transmission of SARS-CoV-2, prevention of COVID-19 following a single intramuscular administration of Adintrevimab, real-world effectiveness of Nirmatrelvir/Ritonavir on COVID-19, and COVID-19 convalescent plasma outpatient therapy to prevent outpatient hospitalization. [...] read more...
BTN #6: Do We Really Need a Yearly COVID Vaccine?
BTN #6: Do We Really Need a Yearly COVID Vaccine?June 21, 2023Paul explains the decision on June 15th 2023 by an FDA Vaccine Advisory Committee to pick the strain for “this year’s” SARS-CoV-2 vaccine, and who it is recommended for. [...] read more...
TWiN 41: Alzheimer’s and melanin-concentrating hormone
TWiN 41: Alzheimer’s and melanin-concentrating hormoneJune 20, 2023Vivianne explains how early in Alzheimer’s disease, the brain attempts to counteract the increased excitatory drive caused by amyloid deposition, and that melanin-concentrating hormone, produced during sleep, is involved in this protective response. [...] read more...
TWiV 1017: From Nature, not a lab
TWiV 1017: From Nature, not a labJune 18, 2023Vincent travels to the University of Pennsylvania to meet up with Susan, Rick, Gigi and David to discuss the origin of SARS-CoV-2, how the FBI might have reached its conclusion on the matter, and public and political perception of scientific risk. [...] read more...
TWiV 1016: Clinical update with Dr. Daniel Griffin
TWiV 1016: Clinical update with Dr. Daniel GriffinJune 17, 2023In his weekly clinical update, Dr. Griffin discusses surveillance to track progress toward poliomyelitis eradication, genetic stabilization of attenuated oral vaccines against poliovirus types 1 and 3, evaluation of Oseltamivir used to prevent hospitalization in outpatients with Influenza, viral emissions into the air and environment after SARS-CoV-2 human challenge, has COVID-19 threatened routine childhood vaccination, successful treatment of persistent symptomatic COVID-19 infection with extended duration Nirmatrelvir/Ritonavir, anemia as a risk factor for disease progression in patients admitted for COVID-19, impact of fatigue as the primary determinant of functional limitations among patients with post-COVID-19 syndrome, post-COVID condition in patients with inflammatory rheumatic diseases, outpatient treatment of COVID-19 and incidence of post-COVID-19 condition over 10 months, metformin reduces SARS-CoV-2 in a Phase 3 randomized placebo controlled clinical trial, persistent serum protein signatures define an inflammatory subcategory of long COVID, and the relevance of pacing strategies in managing symptoms of post-COVID-19 syndrome. [...] read more...
Immune 69: Lung cancer and retroviruses
Immune 69: Lung cancer and retrovirusesJune 15, 2023Kevin joins Immune to discuss his work showing that antibodies against endogenous retroviruses promote immunotherapy of lung cancer. [...] read more...
BTN 5: The next wave of severe COVID-19
BTN 5: The next wave of severe COVID-19June 15, 2023In this episode of Beyond the Noise, Dr. Paul Offit discusses a recent meeting of experts at the White House that raised an ominous possibility. [...] read more...
Infectious Disease Puscast #30
Infectious Disease Puscast #30June 13, 2023On episode #30 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 5/24 – 6/7/23. [...] read more...
TWiV 1015: Soldiers & Scientists at USAMRIID
TWiV 1015: Soldiers & Scientists at USAMRIIDJune 11, 2023Vincent and Rich travel to Ft. Detrick to visit USAMRIID and speak with Todd, Crystal, John and Jay about their careers, their research, and the mission of the US Army Medical Institute of Infectious Diseases. [...] read more...
TWiV 1014: Clinical update with Dr. Daniel Griffin
TWiV 1014: Clinical update with Dr. Daniel GriffinJune 10, 2023In his weekly clinical update, Dr. Griffin discusses estimates of SARS-CoV-2 seroprevalence and incidence of primary SARS-CoV-2 infections among blood donors, by COVID-19 vaccination status, smart thermometer–based participatory surveillance to discern the role of children in household viral transmission during the COVID-19 pandemic, COVID-19 vaccine mandates, changing severity and epidemiology of adults hospitalized with COVID-19 in the United States after introduction of COVID-19 vaccines, effectiveness of COVID-19 treatment with Nirmatrelvir–Ritonavir or Molnupiravir among U.S. veterans, national trends in anticoagulation therapy for COVID-19 hospitalized adults in the United States, development of a definition of postacute sequelae of SARS-CoV-2 infection, neuroinflammation after COVID-19 with persistent depressive and cognitive symptoms, long COVID clinical phenotypes up to six months after infection identified by latent class analysis of self-reported symptoms, and coronary microvascular health in symptomatic patients with prior COVID-19 infection. [...] read more...
BTN4: A New, Life-Saving Vaccine for Older Americans
BTN4: A New, Life-Saving Vaccine for Older AmericansJune 8, 2023In this episode of Beyond the Noise, Dr. Paul Offit discusses two newly licensed respiratory syncytial virus vaccines for adults over 60 years of age. [...] read more...
Infectious Disease Puscast #29
Infectious Disease Puscast #29June 7, 2023On episode #29 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 5/11 – 5/23/23. [...] read more...
TWiP 217: ChatGPT solves the case
TWiP 217: ChatGPT solves the caseJune 5, 2023TWiP solves the case of the Man With Dog Exposure, and discuss rapid and spontaneous post-partum clearance of Plasmodium falciparum related to expulsion of the placenta. [...] read more...