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Latest Episodes

    • TWiV 742: De-fusing COVID-19

      TWiV 742: De-fusing COVID-19

      This Week in Virology - April 11, 2021
      • TWiV reviews a drug screen for inhibitors of syncytium formation, the fusing of cells caused by SARS-CoV-2, which reveals that the process is regulated by a calcium-activated ion channel and scramblase that is inhibited by the anti-parasite drug Niclosamide. post
    • TWiM 239: The phoenix of bacteria

      TWiM 239: The phoenix of bacteria

      This Week in Microbiology - April 10, 2021
      • The TWiM team reviews how variants of P. aeruginosa survive antimicrobial treatment, and a decrease in the antimicrobial resistance of the gut microbiome in the presence of the fungus C. albicans. post
    • TWiV 741: COVID-19 clinical update #57 with Dr. Daniel Griffin

      TWiV 741: COVID-19 clinical update #57 with Dr. Daniel Griffin

      This Week in Virology - April 10, 2021
      • In COVID-19 clinical update #57, Daniel Griffin covers children and MIS-C, school opening plans, transmission event with masks, fomite transmission, diagnostic test performance, AZ vaccine and blood clots, and long COVID and the effect of vaccines. post
    • TWiV 740: Complementation will get you everywhere

      TWiV 740: Complementation will get you everywhere

      This Week in Virology - April 8, 2021
      • The Guardians of the TWiV-o-verse discuss the process of codon deoptimization for the production of experimental infectious attenuated viral vaccines, and how a respiratory syncytial virus with 619 base changes was rescued by genomes with very large internal deletions. post
    • TWiV 739: COVID-19 convalescent plasma with Arturo Casadevall

      TWiV 739: COVID-19 convalescent plasma with Arturo Casadevall

      This Week in Virology - April 4, 2021
      • Arturo Casadevall joins TWiV to discuss the use of convalescent plasma to treat COVID-19, including a history of the process, how plasma is prepared and tested, why it is difficult to conduct randomized clinical trials, how this treatment has fared and his hopes for the future. post
    • TWiP 193: A serpiginous trail

      TWiP 193: A serpiginous trail

      This Week in Parasitism - March 29, 2021
      • Audun returns to help solve the case of the Ecuadorean Gentleman Treated for COVID-19, followed by a discussion of the interaction of Blastocystis with the intestinal microbiota and the immune system, and of course a new clinical case from Daniel. post
    • TWiM 238: Parkinson's disease gut microbiome

      TWiM 238: Parkinson's disease gut microbiome

      This Week in Microbiology - March 28, 2021
      • Elio reveals his thoughts on the big themes of modern microbiology, followed by an analysis of the gut microbiome in patients with Parkinson’s disease. post
    • TWiEVO 66: SARS-2-mouse

      TWiEVO 66: SARS-2-mouse

      This Week in Evolution - March 25, 2021
      • Nels and Vincent review a preprint demonstrating that changes in the genomes of the SARS-CoV-2 variants B1.351 and P.1 allow the viruses to reproduce in mouse cells in culture and in laboratory mice. post
    • Immune 43: CAR-NK and CAR-MAC, thinking outside the CAR-T cell box

      Immune 43: CAR-NK and CAR-MAC, thinking outside the CAR-T cell box

      Immune - March 24, 2021
      • On this episode of Immune, Cindy provides an update on CAR-T cell therapy of cancers and introduces two new approaches that utilize NK cells and macrophages and their use in treating solid tumors. post
    • TWiN 16: Neuronal depolarization with Stefano Brigidi

      TWiN 16: Neuronal depolarization with Stefano Brigidi

      This Week in Neuroscience - March 17, 2021
      • Stefano joins TWiN to discuss his work on understanding genomic decoding of neuronal depolarization by stimulus-specific transcriptional regulators. post
    • TWiM 237: Ten years of TWiM, a quality quorum

      TWiM 237: Ten years of TWiM, a quality quorum

      This Week in Microbiology - March 11, 2021
      • To celebrate ten years, TWiM asks former hosts and guests to provide their thoughts on how microbiology has contributed to our understanding of the microbial world. post
    • TWiEVO 65: Variants in the mist

      TWiEVO 65: Variants in the mist

      This Week in Evolution - February 25, 2021
      • Nels and Vincent review evidence that a single amino acid change in the SARS-CoV-2 spike protein has driven adaptation to humans, followed by an update on the status of variants of concern. post
    • TWiM 236: Gossamer wings and symbionts on the sea bottom

      TWiM 236: Gossamer wings and symbionts on the sea bottom

      This Week in Microbiology - February 20, 2021
      • In this episode, hiring and training expectations for future biomedical life sciences faculty, and the roles of bacterial symbionts in deep-sea hydrothermal vent tubeworms. post
    • TWiN 15: Microbiome and neurodevelopment with Helen Vuong

      TWiN 15: Microbiome and neurodevelopment with Helen Vuong

      This Week in Neuroscience - February 17, 2021
      • Helen joins TWiN to discuss her work on understanding how the maternal microbiome modulates fetal neurodevelopment in mice. post
    • TWiP 192: Towel off vigorously

      TWiP 192: Towel off vigorously

      This Week in Parasitism - February 15, 2021
      • The TWiPers solve the case of the Teenager in Malawi with Red Urine, then Audun joins to present our clinical case for this episode. post
    • Immune 42: Evolution of SARS-CoV-2 antibody immunity with Christian Gaebler

      Immune 42: Evolution of SARS-CoV-2 antibody immunity with Christian Gaebler

      Immune - February 13, 2021
      • Christian joins Immune to discuss the humoral memory response in a cohort of 87 individuals 1.3 and 6.2 months after infection with SARS-CoV-2. post
    • Immune 41: Zebrafish immunology with Madina Wane

      Immune 41: Zebrafish immunology with Madina Wane

      Immune - January 25, 2021
      • Madina joins Immune to explain how the immune system of zebrafish gills compares to its functional counterpart in mammals, the lungs, and to discuss a zebrafish model for understanding olfactory loss during COVID-19. post
    • TWiEVO 64: Seeing the lineages for the variants

      TWiEVO 64: Seeing the lineages for the variants

      This Week in Evolution - January 22, 2021
      • Nels and Vincent consider evolution of antibody immunity to SARS-CoV-2, and update the situation on novel virus variants of concern with potentially altered fitness and reactivity with antibodies. post
    • TWiN 14: Reducing Alzheimer-like pathology in mice

      TWiN 14: Reducing Alzheimer-like pathology in mice

      This Week in Neuroscience - January 14, 2021
      • Ori, Jason, and Vincent discuss the use of antibodies to neutralize amyloid-β seeds before their deposition becomes detectable in transgenic mice, and the finding that the preclinical phase of Alzheimer‘s disease may be a late manifestation of earlier pathogenic seed formation. post
    • TWiP 191: Dickson's ocular anomaly

      TWiP 191: Dickson's ocular anomaly

      This Week in Parasitism - January 11, 2021
      • The TWiPers solve the case of the Rural Man from North Carolina with Blurred Vision, and discuss the results of single-cell RNA sequencing of Schistosoma mansoni. post
    • TWiEVO 63: Year of the coronavirus

      TWiEVO 63: Year of the coronavirus

      This Week in Evolution - December 31, 2020
      • Nels and Vincent wrap up 2020 with a discussion of novel variants of SARS-CoV-2 that have emerged in the United Kingdom and South Africa, how to interpret the rapidly emerging genome sequence data and what to look for in the coming weeks as these variants spread across the globe. post
    • Immune 40: COVID-19 nuances

      Immune 40: COVID-19 nuances

      Immune - December 30, 2020
      • Immune reminisces about a year in COVID-19 immunology, Steph's receiving the Pfizer vaccine, and answers to listener questions about a challenge study with common cold CoVs, T cell exhaustion, how CD4 T cells control infections, and more. post
    • TWiN 13: mRNAs for long-term memory

      TWiN 13: mRNAs for long-term memory

      This Week in Neuroscience - December 16, 2020
      • Ori, Jason, Erin, and Vincent dissect a study that utilizes single-cell RNA sequencing to reveal the genes that underlie remote memory storage in the medial prefrontal cortex of the mouse. post
    • TWiP 190: But Doc, what could it be?

      TWiP 190: But Doc, what could it be?

      This Week in Parasitism - December 8, 2020
      • Christina from Glasgow returns to help the TWiPlets solve the case of the Ghanian Woman with Abdominal Mass, followed by discussion of the impact of COVID-19 on malaria morbidity and mortality in Africa. post
    • Urban Agriculture 29: Gotham Greens

      Urban Agriculture 29: Gotham Greens

      Urban Agriculture - March 13, 2018
      • Dickson travels to indoor farm Gotham Greens in Brooklyn, New York to speak with Co-founder and CEO Viraj Puri. post
    • Buckyball viruses

      Buckyball viruses

      Virus Watch - March 12, 2018
      • How to build several types of virus particles using the small, powerful magnets called Buckyballs. post
    • Urban Agriculture 28: The Vertical Farm Institute

      Urban Agriculture 28: The Vertical Farm Institute

      Urban Agriculture - December 23, 2017
      • Daniel joins Dickson and Vincent to talk about the Vertical Farm Institute, which provides advice and planning on the design and construction of indoor farms.  post
    • Urban Agriculture 27: The Next Big Things

      Urban Agriculture 27: The Next Big Things

      Urban Agriculture - November 10, 2017
      • Dickson provides an updates on progress towards establishing long-term, sustainable, local, safe food systems based on indoor farming. post
    • Zika in the guys

      Zika in the guys

      Virus Watch - November 7, 2016
      • In this episode of Virus Watch, we explore the finding that Zika virus infects the testis of mice, causing damage to the organ, reduced sperm production, and less fertility. The important question: does the same happen in humans? post
    • Urban Agriculture 26: Green Sense Farms

      Urban Agriculture 26: Green Sense Farms

      Urban Agriculture - October 18, 2016
      • Dickson and Vincent speak with Robert Colangelo, founding farmer and CEO of Green Sense Farms, the world's largest commercial indoor vertical farm. post
    • Cancer Killing Viruses

      Cancer Killing Viruses

      Virus Watch - October 14, 2016
      • Guest host Lynda Coughlan reviews how oncolytic viruses, which specifically kill tumor cells, are designed and how they work. post
    • Polio in Nigeria

      Polio in Nigeria

      Virus Watch - August 16, 2016
      • Polio returns to Nigeria after two years - but it turns out it had never gone away. post

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MicrobeTV is an independent podcast network for people who are interested in the sciences. Our shows are about science: viruses, microbes, parasites, evolution, urban agriculture, and neuroscience.

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