Madina joins Immune to explain how the immune system of zebrafish gills compares to its functional counterpart in mammals, the lungs, and to discuss a zebrafish model for understanding olfactory loss during COVID-19. post
The TWiVers review Biden's national strategy for COVID-19 responses and pandemic preparedness, and an evaluation of the BinaxNOW rapid antigen test for SARS-CoV-2 infection. post
In COVID-19 clinical update #46, Daniel Griffin discusses the BinaxNow rapid antigen test, efficacy of Bamlanivimab in nursing homes, associations of serum vitamin D concentrations with in-hospital mortality and need for invasive mechanical ventilation, trials of IL-6 receptor antagonists, effects of anticoagulants on in-hospital mortality, and symptom persistence in outpatients. post
Nels and Vincent consider evolution of antibody immunity to SARS-CoV-2, and update the situation on novel virus variants of concern with potentially altered fitness and reactivity with antibodies. post
In this episode, President Biden elevates his science advisor to his Cabinet, a review of the current flu season, the scientific goals of the WHO-convened Global Study of the Origins of SARS-CoV-2, and answers to listener questions. post
The TWiVy team deconstructs CoronaVac, the inactivated SARS-CoV-2 vaccine produced by Sinovac Biotech, and production of multivalent camelid nanobodies that block infection with the virus and suppress selection of neturalization-resistant variants. post
Ori, Jason, and Vincent discuss the use of antibodies to neutralize amyloid-β seeds before their deposition becomes detectable in transgenic mice, and the finding that the preclinical phase of Alzheimer‘s disease may be a late manifestation of earlier pathogenic seed formation. post
The TWiPers solve the case of the Rural Man from North Carolina with Blurred Vision, and discuss the results of single-cell RNA sequencing of Schistosoma mansoni. post
The TWiM team reviews the movie Jezebel, played against the background of the yellow fever epidemic of 1853 in New Orleans, and prokaryotic viperins, ancestors of the eukaryotic enzymes that synthesize antiviral molecules. post
Nels and Vincent wrap up 2020 with a discussion of novel variants of SARS-CoV-2 that have emerged in the United Kingdom and South Africa, how to interpret the rapidly emerging genome sequence data and what to look for in the coming weeks as these variants spread across the globe. post
Immune reminisces about a year in COVID-19 immunology, Steph's receiving the Pfizer vaccine, and answers to listener questions about a challenge study with common cold CoVs, T cell exhaustion, how CD4 T cells control infections, and more. post
TWiM explores the use of a bacterial protein to make highly conductive microbial nanowires, and how modulin proteins seed the formation of amyloid, a key component of S. aureus biofilms. post
Ori, Jason, Erin, and Vincent dissect a study that utilizes single-cell RNA sequencing to reveal the genes that underlie remote memory storage in the medial prefrontal cortex of the mouse. post
Mark Martin returns to TWiM for a discussion of a predatory bacterium appropriately named Vampirococcus lugosii, and Elio reveals how bacteria can be used on the International Space Station to efficiently extract rare earth elements in microgravity. post
Christina from Glasgow returns to help the TWiPlets solve the case of the Ghanian Woman with Abdominal Mass, followed by discussion of the impact of COVID-19 on malaria morbidity and mortality in Africa. post
Daniel joins Nels and Vincent to discuss his new book on army ants, the wickedest insects ever to roam the planet, and his research on them and clonal raider ants. post
Immune catches up on COVID listener email, including discussions about long-term COVID, cross-reactive memory to SARS-CoV-2, common mucosal surfaces, the risky business of peptide mega-pools, immunodominant epitopes and much more. post
Sallie joins Immune to discuss her career, emphasizing the importance of a good mentor and the ability to pivot, and her research, which has focused on mother to child transmission of infectious diseases including HIV/AIDS, CMV, and more recently, COVID-19/SARS-CoV-2. post
In this episode of TWiM, control of Campylobacter in raw chicken by zinc oxide nanoparticles in packaging material, and Salmonella enterica genomes from a 16th century epidemic in Mexico. post
Ori, Jason, and Vincent reveal identification of an orphan receptor that modifies short-term memory in mice, and a mouse model of COVID-19 that includes anosmia or loss of smell. post
Christina from Glasgow joins the TWiPlets to solve the case of the Elderly Gentlemen with Full Body Rash, and to present a new clinical case for listeners to solve. post
Nels and Vincent discuss an opinion piece on 12 evolutionary insights into how the COVID-19 pandemic is shaping human nature, and prolonged SARS-CoV-2 reproduction in an immunosuppressed patient. post
Daniel joins Dickson and Vincent to talk about the Vertical Farm Institute, which provides advice and planning on the design and construction of indoor farms. post
In this episode of Virus Watch, we explore the finding that Zika virus infects the testis of mice, causing damage to the organ, reduced sperm production, and less fertility. The important question: does the same happen in humans? post
Dickson and Vincent speak with Robert Colangelo, founding farmer and CEO of Green Sense Farms, the world's largest commercial indoor vertical farm. post