Latest Podcasts
TWiV 1011: Aquatic virusesMay 28, 2023Vincent travels to Québec City, Canada and the 11th Aquatic Virus Workshop, where he speaks with Fred Aylward and Jed Furman about the research of their laboratories on the ecology and evolution of aquatic viruses and their microbial communities. [...]
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TWiV 1010: Clinical update with Dr. Daniel GriffinMay 27, 2023In his weekly clinical update, Dr. Griffin discusses the CDC HIV surveillance report, FDA voted in favor of approving the Abrysvo vaccine, canine olfactory detection of SARS-CoV-2-infected humans, safety of the BNT162b2 COVID-19 vaccine in children aged 5 to 17 years, and statement on the antigen composition of COVID-19 vaccines. [...]
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BTN 2: Can we make a universal pandemic vaccine?May 23, 2023In part II of ‘A Closer Look at Biden’s $5 Billion “Next Gen Project”, Paul suggests that it might be harder than we think to make a universal pandemic vaccine. [...]
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TWiV 1009: Nidovirus on the waterMay 21, 2023Vincent travels to Montreux, Switzerland and the 16th International Nidovirus Symposium, where he speaks with Maria von Kerkhove, the face of COVID-19 for the World Health Organization, and Kanta Subbarao, Director of the WHO Collaborating Centre on Influenza in Melbourne. [...]
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TWiV 1008: Clinical update with Dr. Daniel GriffinMay 20, 2023In his weekly clinical update, Dr. Griffin discusses variant specific clinical performance of a SARS-CoV-2 rapid antigen test with focus on omicron VOC, ventilation in buildings, COVID-19 mortality among selective serotonin reuptake inhibitor users, risk of post-acute sequelae of SARS-CoV-2 infection associated with pre-coronavirus disease obstructive sleep apnea diagnoses, trajectories of the evolution of post COVID-19 condition, and efficacy of cognitive behavioral therapy targeting severe fatigue following COVID-19. [...]
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Immune 68: Sins and blessings of immunityMay 18, 2023Immune discusses immunological imprinting, also called original antigenic sin, in the context of infection with SARS-CoV-2 and influenza virus. [...]
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TWiV 1007: Fragile DNA, viruses, cancerMay 14, 2023TWiV explains genetic changes in nOPV2 strains that paralyzed children, outbreak of raccoon distemper in Toronto, EcoHealth Alliance gets its NIH grant back, and breakage at chromosomal fragile sites caused by the EBNA1 protein of Epstein-Barr virus as a mechanism for carcinogenesis. [...]
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TWiV 1006: Clinical update with Dr. Daniel GriffinMay 13, 2023In his weekly clinical update, Dr. Griffin discusses immunogenicity and tolerability of a bivalent virus-like particle norovirus vaccine candidate in children from 6 months up to 4 years of age, influenza hemagglutinin stem nanoparticle vaccine induces cross-group 1 neutralizing antibodies in healthy adults, COVID-19 surveillance after expiration of the public health emergency declaration, provisional mortality data, targeted vaccine messaging to promote COVID-19 vaccines for children and youth, vaccines and related biological products advisory committee meeting June 15, 2023 announcement, how to overhaul the CDC, impact of SARS-CoV-2 variants on inpatient clinical outcome, prevalence of post-coronavirus disease condition 12 weeks after Omicron infection compared with negative controls and association with vaccination status, gut bacteria cocktail helps long COVID, and gut microbiota‐derived symbiotic formula (SIM01) as a novel adjuvant therapy for COVID‐19. [...]
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TWiN 40: Dopamine organizes behavior’s syllablesMay 11, 2023Tim takes TWiN through two studies on the role of dopamine: that syllables are natural units of spontaneous behavior used by the brain to structure action, and that mesolimbic dopamine release conveys causal associations but not reward prediction errors, thereby challenging the dominant theory of reward learning. [...]
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TWiM 286: Integrons and invasionMay 11, 2023TWiM reveals environmental integrons, bacterial genetic elements notorious for their role in spreading antibiotic resistance, and how Salmonella invasion is controlled by competition among intestinal chemical signals. [...]
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BTN 1: Nasal spray COVID vaccines, hope or hype?May 9, 2023Introducing a new video series based on Paul Offit’s substack, ‘Beyond the Noise’. I mistakenly called it ‘Above the Noise’ in this video. For this first episode Paul explains his thoughts on the White House creation of a $5 billion project to in part create newer, better coronavirus vaccines, including nasal spray vaccines. [...]
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TWiV 1005: COVID T vax and a virus from the blueMay 7, 2023TWiV reveals plankton-infecting relatives of herpesviruses in the sunlit oceans, and a vaccine encoding non-spike T cell antigens that protects animals from severe SARS-CoV-2 infection. [...]
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TWiV 1004: Clinical update with Dr. Daniel GriffinMay 6, 2023In his weekly clinical update, Dr. Griffin discusses the U.S. Food and Drug Administration approving Arexvy: the first respiratory syncytial virus (RSV) vaccine approved for use in the United State, association between SARS-CoV-2 and metagenomic content of samples from the Huanan Seafood Market, researchers disagree over how bad it is to be reinfected and whether COVID-19 can cause lasting changes to the immune system, virtual care and emergency department use during the COVID-19 pandemic among patients of family physicians in Canada, vaccination with BCG-Denmark did not result in a lower risk of COVID-19 among health care workers than placebo, NVX-CoV2373 vaccine efficacy against hospitalization, comparative effectiveness of the SARS-COV-2 vaccines during Delta dominance, assessment of gender-specific COVID-19 case fatality risk per malignant neoplasm type, clinical outcomes following treatment for COVID-19 with Nirmatrelvir/Ritonavir and Molnupiravir among patients living in nursing homes, timing of intubation and ICU mortality in COVID-19 patients, real-life experience with Remdesivir for treatment of COVID-19 among older adults, and how long COVID brain fog and muscle pain are associated with longer time to clearance of SARS-CoV-2 RNA from the upper respiratory tract during acute infection. [...]
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Immune 67: Can T cells live forever?May 3, 2023Immune explains the results of a study which show that in mice, functional T cells respond to vaccination for over 10 years and 51 successive immunizations, exhibiting supernumerary cell division and longevity. [...]
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Infectious Disease Puscast #27May 2, 2023On episode #27 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the previous two weeks, 4/13 – 4/25/23. [...]
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TWiP 216: A challenging caseMay 1, 2023Eyal joins TWiP to solve the case of the case of the Feverish Patient from Israel, and reveals his training and experience with travel medicine in Israel. [...]
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TWiV 1003: Going clinically viralApril 30, 2023Vincent and Kathy travel to Atlanta for APHL ID Lab Con, a conference focused on the latest developments in detection and characterization of infectious diseases of public health concern, and speak with Megan, Ryan, and Kirsten about the workings of public health and clinical laboratories. [...]
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TWiV 1002: Clinical update with Dr. Daniel GriffinApril 29, 2023In his weekly clinical update, Dr. Griffin discusses completeness and spin of medRxiv preprints and associated published abstracts of COVID-19 randomized clinical trials, lessons learned from a COVID-19 dog screening pilot in California K-12 schools, SARS-CoV-2 reinfection and severity… [...]
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TWiN 39: Virus-like capsids trigger paraneoplastic diseaseApril 26, 2023Junjie from Jason’s lab joins TWiN to discuss the observation that the cell gene PNMA2 encodes non-enveloped virus-like capsids that induce autoantibodies which underlie paraneoplastic syndrome. [...]
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TWiM 285: How plague got deadlyApril 26, 2023TWiM reveals a new type of satellite virus that requires only phage tails for producing infectious virus particles, and that highly virulent plague bacteria differs from its innocuous enteric predecessor by its resistance to lysis by human complement. [...]
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