Immune 39: A Tonka Truck full of salt
- Immune catches up on COVID listener email, including discussions about long-term COVID, cross-reactive memory to SARS-CoV-2, common mucosal surfaces, the risky business of peptide mega-pools, immunodominant epitopes and much more. post
TWiV 687: Peter Hotez sticks to the vax
- Peter Hotez joins TWiV to discuss the COVID-19 pandemic, including why it went out of control in the US, the hijacking of public health practices by anti-science extremist groups, prospects for control, and whether we will be prepared for the next one. post
Immune 38: COVID-19 and kids with Sallie Permar
- Sallie joins Immune to discuss her career, emphasizing the importance of a good mentor and the ability to pivot, and her research, which has focused on mother to child transmission of infectious diseases including HIV/AIDS, CMV, and more recently, COVID-19/SARS-CoV-2. post
TWiV 686: COVID-19 clinical update #38 with Dr. Daniel Griffin
- Daniel Griffin provides his weekly clinical report on COVID-19, including new post-exposure guidelines from CDC, clinical trials of Remdesivir and convalescent plasma, FDA EUA for baricitinib and Regeneron's monoclonal antibody and more. post
TWiM 230: Ancient bacterial DNA
- In this episode of TWiM, control of Campylobacter in raw chicken by zinc oxide nanoparticles in packaging material, and Salmonella enterica genomes from a 16th century epidemic in Mexico. post
TWiV 685: Pandemicky
- The TWiVers analyze efficacy of the AstraZeneca/Oxford adenovirus vectored vaccine, SARS-CoV-2 did not infect miners who became ill 8 years ago after cleaning bat guano from a cave in Yunnan Province, and induction of antigen-specific germinal center responses and production of neutralizing antibody by SARS-CoV-2 mRNA vaccine but not purified protein. post
TWiV 684: Persistence of SARS-CoV-2 immune memory
- Daniel Griffin provides a clinical report on COVID-19, and Shane Crotty explains a study of antibodies, B cells and T cells in patients which suggests that immunological memory to SARS-CoV-2 might be long-lived. post
Immune 37: Black in Immuno
- Alexis, Joel, Elaine, Justine, and Evonne join Immune to discuss their careers, their research, and a platform created by a collective of Black immunologists and allies aimed at amplifying, celebrating and supporting Black voices in immunology. post
TWiN 12: A gene for short-term memory
- Ori, Jason, and Vincent reveal identification of an orphan receptor that modifies short-term memory in mice, and a mouse model of COVID-19 that includes anosmia or loss of smell. post
TWiP 189: Toe jammin'
- Christina from Glasgow joins the TWiPlets to solve the case of the Elderly Gentlemen with Full Body Rash, and to present a new clinical case for listeners to solve. post
TWiM 229: Dirt is not simple
- In this episode of TWiM, the hidden biochemical diversity in soil-dwelling Actinobacteria that could lead to a second Golden Era of antibiotic discovery, and structures of glideosome components reveals the mechanism of gliding in apicomplexan parasites. post
TWiEVO 61: Shot and chaser of SARS-CoV-2 evolution
- Nels and Vincent discuss an opinion piece on 12 evolutionary insights into how the COVID-19 pandemic is shaping human nature, and prolonged SARS-CoV-2 reproduction in an immunosuppressed patient. post
TWiM 228: Black in Microbiology with Ninecia Scott and Chelsey Spriggs
- Ninecia and Chelsey, two of the founders of Black in Microbiology, join TWiM to discuss the goals of the organization, then we reveal survival of Deinococcus bacteria for 3 years in space, an experiment that addresses the panspermia hypothesis for interplanetary transfer of life. post
Immune 36: Aberrant immunity in COVID-19
- Immune describes the striking loss of germinal centers in lymph nodes and spleen in patients with severe COVID-19, providing an explanation for short-lived humoral immunity and limited somatic hypermutation of antibodies to SARS-CoV-2. post
TWiN 11: A dollar per neuron
- Maria joins TWiN to explain how single-cell transcriptomics is being used to reveal the evolution of the brain, at a cost of about $1 per neuron. post
TWiM 227: The light and dark sides of the fungal world
- TWiM presents an episode for mycophiles: how bacteria disarm mushroom pathogens, and the role of the CARD9 protein in protective immunity against pulmonary cryptococcosis. post
TWiN 10: Remodeling synapses with a cytokine
- TWiN explains how a cytokine produced by neurons activates microglia which modify the extracellular matrix and remodel synapses, leading to memory consolidation. post
TWiP 188: Terrible tropisms
- Dickson, Daniel and Vincent solve the case of the Baby with Hydrocephalus, and present a new clinical case for listeners to solve. post
TWiEVO 60: Five years of TWiEVO on the future of our past
- On the fifth anniversary of TWiEVO, Nels and Vincent invite 11 evolutionary biologists to describe exciting future directions for the field and their laboratory in the next five years. post
TWiP 187: Granny's granuloma
- Dickson, Daniel and Vincent solve the case of the Middle Aged Woman with Loss of Vision in One Eye, and discuss the role of heme oxygenase in the various protozoan infections. post
TWiEVO 59: The hypothesis giving tree
- Nels and Vincent answer listener questions and discuss a newly discovered virus of amoeba with a nearly complete ORFan genome: none of the proteins encoded in the viral genome look like any other proteins. post
TWiEVO 58: Not all coronaviruses ACE2 the test
- Simon and Heather join TWiEVO to discuss their analysis of the evolutionary history of ACE2 usage by coronaviruses in the Sarbecovirus genus. post
TWiN 9: COVID-19 neurology with Genna Waldman
- Columbia University Chief Neurology Resident Genna Waldman joins TWiN to explains how her department prepared for COVID-19, and the neurological symptoms associated with the disease. post
TWiP 186: Not rationing rationality
- Dickson, Daniel and Vincent solve the case of the Elder Gardener Feeling Poorly, and discuss the three-dimensional ultrastructure of Plasmodium falciparum during cytokinesis. post
Urban Agriculture 29: Gotham Greens
- Dickson travels to indoor farm Gotham Greens in Brooklyn, New York to speak with Co-founder and CEO Viraj Puri. post
Buckyball viruses
- How to build several types of virus particles using the small, powerful magnets called Buckyballs. post
Urban Agriculture 28: The Vertical Farm Institute
- Daniel joins Dickson and Vincent to talk about the Vertical Farm Institute, which provides advice and planning on the design and construction of indoor farms. post
Urban Agriculture 27: The Next Big Things
- Dickson provides an updates on progress towards establishing long-term, sustainable, local, safe food systems based on indoor farming. post
Zika in the guys
- In this episode of Virus Watch, we explore the finding that Zika virus infects the testis of mice, causing damage to the organ, reduced sperm production, and less fertility. The important question: does the same happen in humans? post
Urban Agriculture 26: Green Sense Farms
- Dickson and Vincent speak with Robert Colangelo, founding farmer and CEO of Green Sense Farms, the world's largest commercial indoor vertical farm. post
Cancer Killing Viruses
- Guest host Lynda Coughlan reviews how oncolytic viruses, which specifically kill tumor cells, are designed and how they work. post
Polio in Nigeria
- Polio returns to Nigeria after two years - but it turns out it had never gone away. post