Latest Podcasts
TWiP 217: ChatGPT solves the caseJune 5, 2023TWiP solves the case of the Man With Dog Exposure, and discuss rapid and spontaneous post-partum clearance of Plasmodium falciparum related to expulsion of the placenta. [...]
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TWiV 1013: Bird flu around the worldJune 4, 2023TWiV reviews remarkable changes in the epidemiology of avian H5N1 influenza virus leading to previously uninfected areas, involvement of previously unaffected wild birds, and devastating outbreaks in farmed poultry, and isolation of a monoclonal antibody… [...]
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TWiV 1012: Clinical update with Dr. Daniel GriffinJune 3, 2023In his weekly clinical update, Dr. Griffin discusses the potential for recurrent Mpox outbreaks among gay, bisexual, and other men who have sex with men, association between SARS-CoV-2 variants and frequency of acute symptoms, prospective study of key correlates for household transmission of SARS-CoV-2, Pfizer’s PAXLOVID™ receiving FDA approval for adult patients at high risk of progression to severe COVID-19, efficacy and safety of antimicrobial stewardship prospective audit and feedback in patients hospitalized with COVID-19, development of a definition of postacute sequelae of SARS-CoV-2 infection, COVID-19 and risk for mental disorders among adults in Denmark, risk of new post-COVID mental disorders higher only in older patients. [...]
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Infectious Disease Puscast #28May 30, 2023On episode #28 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 4/26 – 5/10/23. [...]
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TWiV 1011: Aquatic virusesMay 28, 2023Vincent travels to Québec City, Canada and the 11th Aquatic Virus Workshop, where he speaks with Fred Aylward and Jed Furman about the research of their laboratories on the ecology and evolution of aquatic viruses and their microbial communities. [...]
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TWiV 1010: Clinical update with Dr. Daniel GriffinMay 27, 2023In his weekly clinical update, Dr. Griffin discusses the CDC HIV surveillance report, FDA voted in favor of approving the Abrysvo vaccine, canine olfactory detection of SARS-CoV-2-infected humans, safety of the BNT162b2 COVID-19 vaccine in children aged 5 to 17 years, and statement on the antigen composition of COVID-19 vaccines. [...]
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BTN 2: Can we make a universal pandemic vaccine?May 23, 2023In part II of ‘A Closer Look at Biden’s $5 Billion “Next Gen Project”, Paul suggests that it might be harder than we think to make a universal pandemic vaccine. [...]
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TWiV 1009: Nidovirus on the waterMay 21, 2023Vincent travels to Montreux, Switzerland and the 16th International Nidovirus Symposium, where he speaks with Maria von Kerkhove, the face of COVID-19 for the World Health Organization, and Kanta Subbarao, Director of the WHO Collaborating Centre on Influenza in Melbourne. [...]
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TWiV 1008: Clinical update with Dr. Daniel GriffinMay 20, 2023In his weekly clinical update, Dr. Griffin discusses variant specific clinical performance of a SARS-CoV-2 rapid antigen test with focus on omicron VOC, ventilation in buildings, COVID-19 mortality among selective serotonin reuptake inhibitor users, risk of post-acute sequelae of SARS-CoV-2 infection associated with pre-coronavirus disease obstructive sleep apnea diagnoses, trajectories of the evolution of post COVID-19 condition, and efficacy of cognitive behavioral therapy targeting severe fatigue following COVID-19. [...]
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Immune 68: Sins and blessings of immunityMay 18, 2023Immune discusses immunological imprinting, also called original antigenic sin, in the context of infection with SARS-CoV-2 and influenza virus. [...]
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TWiV 1007: Fragile DNA, viruses, cancerMay 14, 2023TWiV explains genetic changes in nOPV2 strains that paralyzed children, outbreak of raccoon distemper in Toronto, EcoHealth Alliance gets its NIH grant back, and breakage at chromosomal fragile sites caused by the EBNA1 protein of Epstein-Barr virus as a mechanism for carcinogenesis. [...]
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TWiV 1006: Clinical update with Dr. Daniel GriffinMay 13, 2023In his weekly clinical update, Dr. Griffin discusses immunogenicity and tolerability of a bivalent virus-like particle norovirus vaccine candidate in children from 6 months up to 4 years of age, influenza hemagglutinin stem nanoparticle vaccine induces cross-group 1 neutralizing antibodies in healthy adults, COVID-19 surveillance after expiration of the public health emergency declaration, provisional mortality data, targeted vaccine messaging to promote COVID-19 vaccines for children and youth, vaccines and related biological products advisory committee meeting June 15, 2023 announcement, how to overhaul the CDC, impact of SARS-CoV-2 variants on inpatient clinical outcome, prevalence of post-coronavirus disease condition 12 weeks after Omicron infection compared with negative controls and association with vaccination status, gut bacteria cocktail helps long COVID, and gut microbiota‐derived symbiotic formula (SIM01) as a novel adjuvant therapy for COVID‐19. [...]
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TWiEVO 90: The mystery of the mouse mummiesMay 12, 2023Nels and Vincent provide insights into the mystery of mouse mummies on the summits of >6000 m Andean volcanoes, including whether they were living there and if so why? [...]
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TWiN 40: Dopamine organizes behavior’s syllablesMay 11, 2023Tim takes TWiN through two studies on the role of dopamine: that syllables are natural units of spontaneous behavior used by the brain to structure action, and that mesolimbic dopamine release conveys causal associations but not reward prediction errors, thereby challenging the dominant theory of reward learning. [...]
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TWiM 286: Integrons and invasionMay 11, 2023TWiM reveals environmental integrons, bacterial genetic elements notorious for their role in spreading antibiotic resistance, and how Salmonella invasion is controlled by competition among intestinal chemical signals. [...]
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BTN 1: Nasal spray COVID vaccines, hope or hype?May 9, 2023Introducing a new video series based on Paul Offit’s substack, ‘Beyond the Noise’. I mistakenly called it ‘Above the Noise’ in this video. For this first episode Paul explains his thoughts on the White House creation of a $5 billion project to in part create newer, better coronavirus vaccines, including nasal spray vaccines. [...]
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TWiV 1005: COVID T vax and a virus from the blueMay 7, 2023TWiV reveals plankton-infecting relatives of herpesviruses in the sunlit oceans, and a vaccine encoding non-spike T cell antigens that protects animals from severe SARS-CoV-2 infection. [...]
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TWiV 1004: Clinical update with Dr. Daniel GriffinMay 6, 2023In his weekly clinical update, Dr. Griffin discusses the U.S. Food and Drug Administration approving Arexvy: the first respiratory syncytial virus (RSV) vaccine approved for use in the United State, association between SARS-CoV-2 and metagenomic content of samples from the Huanan Seafood Market, researchers disagree over how bad it is to be reinfected and whether COVID-19 can cause lasting changes to the immune system, virtual care and emergency department use during the COVID-19 pandemic among patients of family physicians in Canada, vaccination with BCG-Denmark did not result in a lower risk of COVID-19 among health care workers than placebo, NVX-CoV2373 vaccine efficacy against hospitalization, comparative effectiveness of the SARS-COV-2 vaccines during Delta dominance, assessment of gender-specific COVID-19 case fatality risk per malignant neoplasm type, clinical outcomes following treatment for COVID-19 with Nirmatrelvir/Ritonavir and Molnupiravir among patients living in nursing homes, timing of intubation and ICU mortality in COVID-19 patients, real-life experience with Remdesivir for treatment of COVID-19 among older adults, and how long COVID brain fog and muscle pain are associated with longer time to clearance of SARS-CoV-2 RNA from the upper respiratory tract during acute infection. [...]
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Immune 67: Can T cells live forever?May 3, 2023Immune explains the results of a study which show that in mice, functional T cells respond to vaccination for over 10 years and 51 successive immunizations, exhibiting supernumerary cell division and longevity. [...]
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Infectious Disease Puscast #27May 2, 2023On episode #27 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the previous two weeks, 4/13 – 4/25/23. [...]
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