Peter Hotez joins TWiV to discuss the COVID-19 pandemic, including why it went out of control in the US, the hijacking of public health practices by anti-science extremist groups, prospects for control, and whether we will be prepared for the next one.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Brianne Barker

Guest: Peter Hotez

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Download TWiV 687 (83 MB .mp3, 138 min)
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Weekly Science Picks 2:06:06

DicksonThe World’s First Energy-Positive Hotel to Open in Norway
BrianneThe Food Lab: Better Home Cooking Through Science
AlanACIP’s ethical principles for COVID-19 vaccine allocation
RichThe Mandolorian
VincentT. rex and the Crater of Doom by Walter Alvarez

Intro music is by Ronald Jenkees

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Daniel Griffin provides his weekly clinical report on COVID-19, including new post-exposure guidelines from CDC, clinical trials of Remdesivir and convalescent plasma, FDA EUA for baricitinib and Regeneron’s monoclonal antibody and more.

Hosts: Daniel Griffin and Vincent Racaniello

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Download TWiV 686 (21 MB .mp3, 35 min)
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Intro music is by Ronald Jenkees

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The TWiVers analyze efficacy of the AstraZeneca/Oxford adenovirus vectored vaccine, SARS-CoV-2 did not infect miners who became ill 8 years ago after cleaning bat guano from a cave in Yunnan Province, and induction of antigen-specific germinal center responses and production of neutralizing antibody by SARS-CoV-2 mRNA vaccine but not purified protein.

Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker

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Download TWiV 685 (66 MB .mp3, 110 min)
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Weekly Picks 1:40:35

BrianneTypes of Scientists Coloring Book
KathySouth Pole video
RichSteve Jobs by Walter Isaacson
VincentScreenology (I interviewed Deb Sklut here)

Listener Pick

MonaAd5 vector and podcast with ImmunityBio founder

Intro music is by Ronald Jenkees

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Daniel Griffin provides a clinical report on COVID-19, and Shane Crotty explains a study of antibodies, B cells and T cells in patients which suggests that immunological memory to SARS-CoV-2 might be long-lived.

Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Brianne Barker

Guests: Daniel Griffin and Shane Crotty

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Download TWiV 684 (110 MB .mp3, 184 min)
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Weekly Science Picks 2:44:51

DicksonBenoit Mandlebrot’s 96 birthday
Brianne#BlackinImmunoWeek
RichGoISSWatch ISS Tracking; Spot The Station (NASA)
VincentMicrobes Rule

Listener Pick

AgdaSandwalk

Intro music is by Ronald Jenkees

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On this episode of TWiV, mRNA vaccines from Moderna and Pfizer show over 90% efficacy, prothrombotic auto-antibodies in serum of COVID-19 patients, and the whereabouts of SARS-CoV-2 in the human body.

Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker

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Download TWiV 683 (72 MB .mp3, 119 min)
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Weekly Picks 1:43:25

BriannePicture a Scientist
KathyColors of the Moon and Word that hasn’t changed
RichNASA YouTube channel
VincentLaura Splan science art

Listener Pick

MonaAd5 vector and podcast with ImmunityBio founder

Intro music is by Ronald Jenkees

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From Expedition 64 of International Space Station, Flight Engineer Kate Rubins joins TWiV to discuss experiments that she is working on, including cell cultures, genome sequencing, and plant growth.

Hosts: Vincent Racaniello and Rich Condit

Guest: Kate Rubins

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Download TWiV 682 (17 MB .mp3, 29 min)
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Intro music is by Ronald Jenkees

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Daniel Griffin provides a clinical report on COVID-19, Kathleen Crowley explains the role of Environmental Health & Safety departments, update on SARS-CoV-2 transmission in farmed mink, and the presence of pre-existing antibodies to SARS-CoV-2 in unexposed individuals.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Brianne Barker

Guests: Daniel Griffin and Kathleen A. Crowley

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Download TWiV 681 (107 MB .mp3, 179 min)
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Weekly Science Picks 2:33:04

DicksonOSIRIS-REx | NASA
BrianneVirtual Science Museum Tours
AlanRing Fit Adventure
RichBUGSS Baltimore Underground Science Space
VincentTrilobite glassworks

Listener Pick

Gina and JoeCOVID Fan Tutte

Intro music is by Ronald Jenkees

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Mady, Fiona, and David join TWiV to discuss patients with long-term COVID and similarities and differences with ME/CFS.

Hosts: Vincent Racaniello, Rich Condit, and Brianne Barker

Guests: Mady Hornig, Fiona Lowenstein, and David Tuller

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Download TWiV 680 (67 MB .mp3, 112 min)
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Intro music is by Ronald Jenkees

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Daniel Griffin provides a clinical report on COVID-19, Slovlakia’s plan to test all adults for SARS-CoV-2 infection, viral variants arising in Danish mink and their potential threat to humans, why it is unethical to carry out challenge trials, Nipah virus dynamics in bats and spillovers into humans, and direct cardiac damage by spike-mediated cardiomyocyte fusion.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Brianne Barker

Guests: Daniel Griffin and Amy Rosenfeld

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Download TWiV 679 (94 MB .mp3, 157 min)
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Weekly Science Picks 2:14:46

DicksonCNN News
AmyI voted and Grace for President
AlanThe Story of More by Hope Jahren
RichOSIRIS-REx and 101955 Bennu
VincentThe Vexed Muddler

Intro music is by Ronald Jenkees

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Nels joins TWiV to reveal the discovery of a picornavirus of zebrafish by measuring immune responses in the host, genome sequence analysis of the White House COVID-19 outbreak, and a six-fold higher SARS-CoV-2 exposure rate than reported cases in German children.

Hosts: Vincent Racaniello, Rich Condit, and Kathy Spindler

Guest: Nels Elde

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Download TWiV 678 (67 MB .mp3, 111 min)
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Weekly Science Picks 58:37, 1:42:57

Kathy –  Why art is important and Tagging an asteroid
RichVendee Globe
VincentPrePubMed

Intro music is by Ronald Jenkees

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