TWiV 886: COVID-19 clinical update #109 with Dr. Daniel Griffin

In COVID-19 clinical update #109, Daniel Griffin discusses cardiac complications after infection or vaccination, long COVID in children, fourth vaccine dose in Israel, no need for fourth vaccine does in EU, dexamethasone dosing, immunomodulation therapy, MIS outcomes in children, US long COVID effort launched, and herd immunity.

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Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV 885: Russian bats and Ankara vectors

TWiV reveals an ACE2-dependent sarbecovirus from Russian bats that is not inhibited by anti-SARS-CoV-2 antibodies, and a modified vaccinia virus Ankara vectored vaccine that protects nonhuman primates from Delta infection.

Hosts: Vincent Racaniello, Rich Condit, and Brianne Barker

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Weekly Picks 1:25:27

Brianne – The Search for a Model Octopus That Won’t Die After Laying Its Eggs
Rich – Vaccine Pioneers and Opponents with Paul Offit (Podcast: Connected by Controversy by Chris White)  and The Cutter Incident by Paul Offit
Vincent – Simply Put: Vaccines Save Lives

Listener Picks

Rich – ‘Stolen’ Charles Darwin notebooks left on library floor in pink gift bag
Neva – Elin Thomas, UK textile artist
Viki – History of English Podcast

Intro music is by Ronald Jenkees

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TWiV 884: Cytokines and viral mimicry

Vincent and Amy explain how asthmatic bronchial smooth muscle increases rhinovirus replication in the bronchial epithelium, and mimicry of IL-17 by the ORF8 protein of SARS-CoV-2.

Hosts: Vincent Racaniello and Amy Rosenfeld

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Weekly Picks 1:37:40

Amy – Ben Franklin by Ken Burns
Vincent – Thoughts on a second booster: Offit and Krause/Borio

Listener Picks

Philip – History of Clemson Blue Cheese
Jack – Pipeline and A Special Report on Polio

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

TWiV 883: COVID-19 clinical update #108 with Dr. Daniel Griffin

In COVID-19 clinical update #107, Daniel Griffin reviews vaccine booster doses, at-home testing, transmission in hamsters, improving indoor air quality, trials of BCG, ivermectin, and fluvoxamine, vaccination during pregnancy, mRNA vaccines and Fc functions, anti-platelet and aspirin therapy and a trial of prone positioning.

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Download TWiV 883 (27 MB .mp3, 45 min)
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Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV 882: Elispot on about T cells and lipids

Vincent and Brianne review the need to better understand T cell responses to SARS-CoV-2 infection to better inform public health decisions, and how IL-1 and IL-1ra are important regulators of the inflammatory response to RNA vaccines.

Hosts: Vincent Racaniello and Brianne Barker

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Weekly Picks 1:37:33

Brianne – Covid restrictions prevented dengue in hundreds of thousands of people in 2020
Vincent – Scotch Dual Lock 250 Reclosable Fastener

Listener Picks

Erin –JWT Preparation and Xploration Outer Space

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

TWiV 881: 50 ways to zap your virus

TWiV describes the identification of a monoclonal antibody that provides broad protection against a variety of hantaviruses, and development of an oral remdesivir-like antiviral that ameliorates viral disease in mice.

Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Amy Rosenfeld

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Weekly Picks 1:35:55

Dickson – World’s tallest wooden building
Amy – Virus hunter in the Wuhan market
Rich – WorldPop (example)
Vincent – Karst Stone Paper

Listener Picks

Neva – Can we vaccinate against EBV? and Paul Sutter reading a science paper

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

TWiV 880: COVID-19 clinical update #107 with Dr. Daniel Griffin

In COVID-19 clinical update #107, Daniel Griffin discusses Moderna vaccine results in children, hospitalization by ethnicity, BA.2 severity in children, placentitis and thrombohematoma during pregnancy, predictive value of symptoms for diagnosis, Evusheld activity against BA.1 and BA.2, Remdesivir resistance, Ivermectin with and without strongyloidiasis, inhaled ciclesonide, home telemonitoring, pulse oximetry for remote monitoring, effectiveness of anti-platelet therapy, and deaths in Zambia.

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Download TWiV 880 (57 MB .mp3, 48 min)
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Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV 879: Indolent, resistant, and losing our TMPRSS

TWiV reviews the emergence of remdesivir-resistant SARS-CoV-2 during treatment of a persistently infected immunocompromised patient, and how altered TMPRSS2 utilization by the Omicron variant influences infectivity and fusion.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Kathy Spindler, and Brianne Barker

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Weekly Picks 1:21:44

Brianne – NSURP 2022
Kathy – Virology Jobs
Rich – 10 Steps from Seed to Cup (Graphic)
Alan – Fathoms: The World in The Whale, by Rebecca Giggs
Vincent – Worldwaterday.org

Listener Picks

Jeremy – Archaeology of Light

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

TWiV 878: Shape matters sometimes

TWiV revisits chronic wasting disease of cervids and the ability of the prions to infect meadow voles and raccoons, and the suggestion that stochastic assembly of influenza virus particles may play a role in phenotypic diversity.

Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Amy Rosenfeld

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Download TWiV 878 (75 MB .mp3, 124 min)
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Weekly Picks 1:30:35, 1:39:29

Dickson – James Webb Space Telescope and Nature Conservancy Photo Contest
Amy – A new strategy for staying one step ahead of the virus
Rich – Searching for the origin of the smallpox vaccine: Edward Jenner and his little-known horsepox hypothesis
Vincent – Blacktail Studio

Listener Picks

Richard – Water Structure and Science

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

TWiV 877: COVID-19 clinical update #106 with Dr. Daniel Griffin

In COVID-19 clinical update #106, Daniel Griffin covers failure of ivermectin to improve hospitalization, increased hospitalization of children with Omicron, seroconversion of children versus adults, effectiveness of Pfizer mRNA vaccine in children, high vaccine effectiveness in Finland against Omicron, distinct long COVID clinical phenotypes, and estimating worldwide excess mortality.

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Download 877 (17 MB .mp3, 28 min)
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Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Questions or comments

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