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Vincent, Rich, and Brianne discuss a study estimating the fraction of symptoms and severe disease after SARS- CoV-2 infection, cellular immune responses without seroconversion during interfamilial infections, and answer listener email.

Hosts: Vincent Racaniello, Rich Condit, and Brianne Barker

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Download TWiV 631 (72 MB .mp3, 119 min)
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Intro music is by Ronald Jenkees

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From the Environmental Health Institute in Singapore, Vincent speaks with Director Lee Ching Ng about their work to control viral infectious diseases, including the controlled release of mosquitoes containing Wolbachia endosymbionts to inhibit viral transmission.

Host: Vincent Racaniello

Guest: Lee Ching Ng

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Download TWiV 630 (29 MB .mp3, 49 min)

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Daniel Griffin provides a clinical update on COVID-19, including analysis of the dexamethasone trial, and then we discuss two Ebolavirus outbreaks in DRC, clinical and virological aspects of asymptomatic SARS-CoV-2 infections, age-dependent effects on transmission, and answer listener email.

Hosts: Vincent Racaniello, Dickson Despommier, and Alan Dove

Guests: Daniel Griffin and Chuck Knirsch

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Download TWiV 629 (95 MB .mp3, 158 min)
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Intro music is by Ronald Jenkees

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CoV_bank

Vincent and Rich discuss the SARS-CoV-2 D614G amino acid change in the spike glyprotein, duration of infectious virus shedding from patients, virus transmission among hamsters infected in the laboratory, and tackle listener email.

Hosts: Vincent Racaniello and Rich Condit

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Download TWiV 628 (68 MB .mp3, 113 min)

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Intro music is by Ronald Jenkees

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Vincent visits the National Centre for Infectious Diseases and speaks with Executive Director Leo Yee-Sin and Consultant Nancy Tee about the main hub for both clinical treatment of infectious diseases and outbreak management in Singapore.

Host: Vincent Racaniello

Guests: Leo Yee-Sin and Nancy Tee

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Download TWiV 627 (54 MB .mp3, 91 min)
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Intro music is by Ronald Jenkees

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MicrobeTV condemns violence of any kind and will commit resources as an educational platform to support the African American community and people of color worldwide. Black Lives Matter, and our hearts, our support and our solidarity are with everyone who suffers from racial injustice.  Human dignity starts with the singular premise that we are all the same, no matter our skin color, religion, sex, gender, or where we live. At all times and in all circumstances, people are entitled to respect, and humane treatment especially by those in position of authority. MicrobeTV says “no more” racism and we will work with educators, scientists and civil society globally to do what is in our power to end social injustice in all its forms.

Daniel Griffin provides a clinical update on COVID-19, then Ralph Baric joins TWiV to discuss SARS-CoV-2 transmission, vaccines, diagnostic tests, and a new animal model from his laboratory that does not use transgenic mice.

Note: Daniel’s update is in the audio only version of this episode.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Brianne Barker

Guests: Daniel Griffin, Chuck Knirsch, and Ralph Baric

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Download TWiV 626 (98 MB .mp3, 163 min)
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Intro music is by Ronald Jenkees

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Vincent and Rich visit Fred Murphy to hear about his wide-ranging career in virology, spanning many institutions, involving dangerous viruses like rabies virus, Ebolavirus (he took that famous iconic image), Marburg virus, Lassa virus, coronaviruses, and later writing a history of the field.

Hosts: Vincent Racaniello and Rich Condit

Guest: Frederick A. Murphy

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Download TWiV 625 (60 MB .mp3, 100 min)
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Intro music is by Ronald Jenkees
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Daniel Griffin provides a clinical update on COVID-19, then Sabra Klein joins us to discuss the effect of sex, gender, and age on viral infectious disease, including COVID-19.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, Kathy Spindler and Brianne Barker

Guests: Daniel Griffin, Chuck Knirsch, and Sabra Klein

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Download TWiV 624 (74 MB .mp3, 123 min)
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Peter Daszak joins TWiV to explain the work of EcoHealth Alliance in surveillance of bats in China for SARS-related coronaviruses to provide the information needed to prevent future pandemics, and why NIH recently withdrew financial support for their work.

Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker

Guest: Peter Daszak

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Download TWiV 623 (41 MB .mp3, 68 min)
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Intro music is by Ronald Jenkees

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CoV_bank

Emmie de Wit joins TWiV to explain her work on the pathogenesis of infection with SARS-CoV-2 in rhesus macaques, including studies on remdesivir and vaccine candidate.

Hosts: Vincent Racaniello, Rich Condit, and Brianne Barker

Guest: Emmie de Wit

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Download TWiV 622 (41 MB .mp3, 68 min)
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Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv