TWiV 876: Spillover market with Michael Worobey

Michael Worobey joins TWiV to explain evidence that SARS-CoV-2 emerged via the wildlife trade and that the Huanan market was the unambiguous epicenter of the COVID-19 pandemic.

Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker

Guest: Michael Worobey

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Weekly Picks 1:26:55

Brianne – Kartchner Caverns (info from Wikipedia here)
Kathy – Laminar flow and turbulent flow
Rich – Wikipedia
Vincent – The Human Lake by Carl Zimmer

Listener Picks

Brad – NASASpaceflight

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

TWiV 875: Animal house

TWiV discusses the virome of game animals in China, and the finding that binding of sarbecoviruses to ACE2 is an ancestral and evolvable trait.

Hosts: Vincent Racaniello, Dickson Despommier, and Amy Rosenfeld

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Weekly Picks 1:13:59

Dickson – Ship found at the bottom of the sea
Amy – Vaccinating kids has never been easy
Vincent – State data and CDC data on children and COVID-19

Listener Picks

Andrew – Books by Randall Munroe

Intro music is by Ronald Jenkees

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TWiV 874: COVID-19 clinical update #105 with Dr. Daniel Griffin

In COVID-19 clinical update #105, Daniel Griffin discusses changes in brain structure after infection, dementia in patients with pneumonia, Paxlovid in children, mask effectiveness in schools, host factors and severe disease, post-acute symptoms, and the mission of CEPI.

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Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV 873: Pig viruses and big viruses

TWiV reviews the six known coronaviruses that infect pigs and what can be learned about human infections, and how the giant Mimivirus DNA genome is organized into a nucleocapsid.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker

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Weekly Picks 1:38:46

Brianne – The Dinosaur Age May Have Ended in Springtime
Alan – The Track of the Typhoon, and me reading it.
Rich – 12 Monkeys
Vincent – Anna Mason’s Art Channel

Listener Picks

Richard – SARS-CoV-2 in animals: Situation report #9
Jason – Counting App and CountThings from Photos

Intro music is by Ronald Jenkees

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TWiV 872: COVID-19 clinical update #104 with Dr. Daniel Griffin

In COVID-19 clinical update #104, Daniel Griffin reviews effectiveness of mRNA vaccines among children, number of children affected by disease, accuracy of rapid antigen tests, CDC guidance for prevention strategies, monoclonal antibody effectiveness, predicting progression to severe respiratory failure from pneumonia, risk of long COVID after two vaccine doses, and peripheral neuropathy in long COVID.

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Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV 871: If the ACE2 fits, ferret

TWiV discusses whether or not Omicron should be designated a new serotype of SARS-CoV-2, and the finding that amino acid changes that adapt SARS-CoV-2 to mink or ferret do not increase fitness in the human airway.

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

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Weekly Picks 1:27:34

Alan – Which Immune Cell Are You? and Michaeleen Doucleff’s article
Rich – Vaccinated: One Man’s Quest to Defeat the World’s Deadliest Diseases by Paul A. Offit
Vincent – Ebola on Canvas

Listener Picks

Les – Ologies podcast

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

TWiV 870: COVID-19 clinical update #103 with Dr. Daniel Griffin

In COVID-19 clinical update #103, Daniel Griffin covers immunocompromised people, hospitalization of children, vaccine usage update, Omicron and cross-reactive neutralizing antibodies, reinfection prevents disease in hamsters, repeated infections with endemic coronaviruses, global burden of antimicrobial resistance, ivermectin not protective in hamsters, and Omicron evades therapeutic monoclonals.

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Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV 869: Epstein-Barr virus and MS, a perfect storm

TWiV reviews epidemiological and experimental evidence that infection with Epstein-Barr virus leads to the production of antibodies against a viral protein that cross-react with a human protein, leading to multiple sclerosis.

Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Brianne Barker

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Weekly Picks 1:34:06

Dickson – Rapid intensification of the emerging southwestern North American megadrought in 2020–2021
Brianne – Which Immune Cell Are You?
Rich – Nikola Tesla – 3D Anamorphosis
Vincent – Paul’s Uncle Doesn’t Want to Get Vaccinated

Listener Picks

Bob – The 1969 Apollo Guidance Computer
Anne – Decoding the Gurus with Dan Wilson
Beth – FrenchGuyCooking

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

TWiV 868: COVID-19 clinical update #102 with Dr. Daniel Griffin

In COVID-19 clinical update #102, Daniel Griffin reviews children and COVID, effectiveness of maternal vaccination, vaccines for immunocompromised, primary care physicians and vaccination rates, booster safety among adults, placentitis, azithromycin, oral Nirmatrelvir, Omicron antibody evasion, EUA for bebtelovimab, IL-1 blocking agents, thromboprophylaxis, effectiveness of vaccines against long COVID, and risks of mental health outcomes.

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Download TWiV 868 (58 MB .mp3, 48 min)
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Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV 867: I love the smell of vaccines in the morning

TWiV reviews an experimental, intranasally administered SARS-CoV-2 vaccine that utilizes adenovirus vectors to deliver three viral proteins and induces immunity to ancestral and variant isolates.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler

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Weekly Picks 1:29:40

Kathy – 477-mile-long megaflash lightning in Seattle Times (originally Washington Post) and extra info from Rich World Meteorological Org
Rich – NIAID Global Research (Mali)
Alan – New method for recycling electric car batteries
Vincent – Q&A with A&V

Listener Picks

Addie – Vaccine Podcast
Jennie – Dr. Katelyn Jetelina, aka Your Local Epidemiologist

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

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