Michael Worobey joins TWiV to explain evidence that SARS-CoV-2 emerged via the wildlife trade and that the Huanan market was the unambiguous epicenter of the COVID-19 pandemic.

Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker

Guest: Michael Worobey

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Weekly Picks 1:26:55

BrianneKartchner Caverns (info from Wikipedia here)
Kathy Laminar flow and turbulent flow
RichWikipedia
Vincent The Human Lake by Carl Zimmer

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BradNASASpaceflight

Intro music is by Ronald Jenkees

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TWiV discusses the virome of game animals in China, and the finding that binding of sarbecoviruses to ACE2 is an ancestral and evolvable trait.

Hosts: Vincent Racaniello, Dickson Despommier, and Amy Rosenfeld

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Weekly Picks 1:13:59

DicksonShip found at the bottom of the sea
Amy Vaccinating kids has never been easy
Vincent State data and CDC data on children and COVID-19

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Andrew – Books by Randall Munroe

Intro music is by Ronald Jenkees

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In COVID-19 clinical update #105, Daniel Griffin discusses changes in brain structure after infection, dementia in patients with pneumonia, Paxlovid in children, mask effectiveness in schools, host factors and severe disease, post-acute symptoms, and the mission of CEPI.

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Intro music is by Ronald Jenkees

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TWiV reviews the six known coronaviruses that infect pigs and what can be learned about human infections, and how the giant Mimivirus DNA genome is organized into a nucleocapsid.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker

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Weekly Picks 1:38:46

BrianneThe Dinosaur Age May Have Ended in Springtime
Alan The Track of the Typhoon, and me reading it.
Rich 12 Monkeys
Vincent Anna Mason’s Art Channel

Listener Picks

RichardSARS-CoV-2 in animals: Situation report #9
JasonCounting App and CountThings from Photos

Intro music is by Ronald Jenkees

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In COVID-19 clinical update #104, Daniel Griffin reviews effectiveness of mRNA vaccines among children, number of children affected by disease, accuracy of rapid antigen tests, CDC guidance for prevention strategies, monoclonal antibody effectiveness, predicting progression to severe respiratory failure from pneumonia, risk of long COVID after two vaccine doses, and peripheral neuropathy in long COVID.

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Intro music is by Ronald Jenkees

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TWiV discusses whether or not Omicron should be designated a new serotype of SARS-CoV-2, and the finding that amino acid changes that adapt SARS-CoV-2 to mink or ferret do not increase fitness in the human airway.

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

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Weekly Picks 1:27:34

Alan Which Immune Cell Are You? and Michaeleen Doucleff’s article
Rich Vaccinated: One Man’s Quest to Defeat the World’s Deadliest Diseases by Paul A. Offit
Vincent Ebola on Canvas

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LesOlogies podcast

Intro music is by Ronald Jenkees

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In COVID-19 clinical update #103, Daniel Griffin covers immunocompromised people, hospitalization of children, vaccine usage update, Omicron and cross-reactive neutralizing antibodies, reinfection prevents disease in hamsters, repeated infections with endemic coronaviruses, global burden of antimicrobial resistance, ivermectin not protective in hamsters, and Omicron evades therapeutic monoclonals.

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Intro music is by Ronald Jenkees

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TWiV reviews epidemiological and experimental evidence that infection with Epstein-Barr virus leads to the production of antibodies against a viral protein that cross-react with a human protein, leading to multiple sclerosis.

Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Brianne Barker

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Weekly Picks 1:34:06

Dickson Rapid intensification of the emerging southwestern North American megadrought in 2020–2021
BrianneWhich Immune Cell Are You?
Rich Nikola Tesla – 3D Anamorphosis
Vincent Paul’s Uncle Doesn’t Want to Get Vaccinated

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BobThe 1969 Apollo Guidance Computer
AnneDecoding the Gurus with Dan Wilson
BethFrenchGuyCooking

Intro music is by Ronald Jenkees

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In COVID-19 clinical update #102, Daniel Griffin reviews children and COVID, effectiveness of maternal vaccination, vaccines for immunocompromised, primary care physicians and vaccination rates, booster safety among adults, placentitis, azithromycin, oral Nirmatrelvir, Omicron antibody evasion, EUA for bebtelovimab, IL-1 blocking agents, thromboprophylaxis, effectiveness of vaccines against long COVID, and risks of mental health outcomes.

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Intro music is by Ronald Jenkees

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TWiV reviews an experimental, intranasally administered SARS-CoV-2 vaccine that utilizes adenovirus vectors to deliver three viral proteins and induces immunity to ancestral and variant isolates.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler

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Weekly Picks 1:29:40

Kathy 477-mile-long megaflash lightning in Seattle Times (originally Washington Post) and extra info from Rich World Meteorological Org
RichNIAID Global Research (Mali)
Alan – New method for recycling electric car batteries
Vincent Q&A with A&V

Listener Picks

AddieVaccine Podcast
JennieDr. Katelyn Jetelina, aka Your Local Epidemiologist

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