TWiV 919: Motivated by volatiles

TWiV reviews the FDA decision to update COVID-19 vaccine boosters in the fall, the meaning of fatigue with respect to long COVID, and a skin volatile induced by flavivirus reproduction that attracts mosquitoes to the infected host.

Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker

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Weekly Picks 1:20:34

Brianne – Redactle
Kathy – Kirigami paper replacing plastic bubble wrap
Rich – First Images from the James Webb Space Telescope (Gravitational lens; Einstein ring)
Vincent – Spotted lanternfly

Listener Picks

Ann – NASA Engineer Who Made the James Webb Space Telescope Work
Sonrisa – Aloft – the pleasures and risks of flying

Intro music is by Ronald Jenkees

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TWiV 918: COVID-19 clinical update #123 with Dr. Daniel Griffin

In COVID-19 clinical update #123, Dr. Griffin discusses rapid diagnostic testing in response to the monkeypox outbreak, leading causes of death in the US during the COVID-19 pandemic, antibody evasion by subvariants, broadly-neutralizing antibodies against emerging variants, factors associated with severe outcomes among hospitalized immunocompromised adults, measurement of the burden of hospitalizations during the pandemic, parental vaccine hesitancy in diverse communities, evaluating saliva sampling to improve access to diagnosis in low-resource settings, oral sabizabulin for high-risk hospitalized adults, lower-risk of multisystem inflammatory syndrome in children, and neurovascular injury with complement activation and inflammation during infection.

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Intro music is by Ronald Jenkees

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TWiV 917: Boosters on, Paul Offit

Paul Offit returns to TWiV to discuss why, during the recent FDA advisory committee meeting, he voted against releasing revised COVID-19 vaccines containing an Omicron component, and the reasons why children must be vaccinated against the disease.

Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Kathy Spindler

Guest: Paul Offit

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Weekly Picks 1:20:41

Dickson – Woody Herman and his orchestra. 1955-1965. Signature song: The Preacher. Signature album: Woody Herman and His Orchestra (1956)
Kathy – Solargraphic analemmas
Rich – Windy (desktop; app)
Vincent – Why monkeypox is mostly hitting men who have sex with men

Listener Picks

Mark – Hand Wash Dance – NHK WORLD-JAPAN

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

TWiV 916: COVID-19 clinical update #122 with Dr. Daniel Griffin

In COVID-19 clinical update #122, Dr. Griffin discusses vaccine availability and coverage among children, post-infection health impairments in children and adolescents, infection detection using salvia and nasopharyngeal samples, effectiveness of vaccines during delta dominance, durability of vaccine against severe outcomes, concern in the postvaccination era, infection rebound after Paxlovid & Molnupiravir, lack of improvement after adding ivermectin to standard care, duration of shedding of virus, how thromboprophylaxis reduces thromboembolism but increases major bleeding, multi-lineage neural and myelin dysregulation caused by infection, and the association between vaccination and post-acute infection.

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Intro music is by Ronald Jenkees

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TWiV 915: Mouse mouth to mouse mom

TWiV discusses the recent decision by an FDA advisory committee to update COVID vaccines for the fall, the monkeypox virus outbreak, and the finding that enteric viruses infect the salivary glands and are transmitted through saliva.

Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Kathy Spindler, and Brianne Barker.

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Weekly Picks 1:31:57

Dickson – Jazz big bands #2: Maynard Ferguson: Signature song: Theme From Rocky: Signature album: Color Him Wild
Brianne – Origami antibody and virus
Kathy – Turbines resistant to high winds
Rich – Obi-Wan Kenobi (TV Series)
Vincent – The next epidemic may be here. The US isn’t ready for it.

Listener Picks

David: DALL E 2
Douglas – Jazz Online

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

TWiV 914: COVID-19 clinical update #121 with Dr. Daniel Griffin

In COVID-19 clinical update #121, Dr. Griffin discusses age as a risk factor for severe disease, updated vaccine boosters for the fall, pediatric infection and antibody seroprevalence in Arkansas over the first year of the COVID-19 pandemic, all-cause maternal mortality in the United States before and during the pandemic, and the effect of 2-week interruption in methotrexate treatment and how it impacts vaccine immunity.

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Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV 913: Twinkle twinkle little SARS

TWiV explains the meaning of vaccine-derived poliovirus found in London sewage, risk of long COVID after infections with Delta or Omicron variants of SARS-CoV-2, and enhancers of innate immune signaling as broad-spectrum antivirals.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler.

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Weekly Picks 1:32:46

Dickson – Count Basie: April in Paris
Kathy – Bird aerodynamics & inertia: lay article, video, Nature
Rich – NASA Gateway (Thanks Ellis)
Alan – Polio Eradication in Nigeria
Vincent – The Tyranny of Merit by Michael J. Sandel

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

TWiV 912: COVID-19 clinical update #120 with Dr. Daniel Griffin

In COVID-19 clinical update #120, Dr. Griffin discusses outcomes of SARS-CoV-2 reinfection, CDC recommendation for vaccines in young children, neurodevelopment outcomes in infants of mothers testing positive for COVID during pregnancy, efficacy of monoclonal antibodies and antivirals in hamsters, rebound phenomenon after PAXLOVID in high-risk persons, hospitalization for infection after PAXLOVID treatment, and risk of long COVID with different variants.

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Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

TWiV 911: Antibody can get vaccinated now

TWiV provides an update on hepatitis of unknown etiology in children, an experimental nanoparticle vaccine for Epstein-Barr virus, and minimal impact of bamlanivimab therapy on antiviral antibodies induced by vaccination.

Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker

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Weekly Picks 1:41:20

Brianne – A Frog So Small, It Could Not Frog
Kathy – A Grand Night In: The Story of Aardman
Rich – Archive
Vincent – Bandwagoning by Heran Darwin

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

TWiV 910: COVID-19 clinical update #119 with Dr. Daniel Griffin

In COVID-19 clinical update #119, Dr. Griffin reviews tixagevimab for infection prevention, ivermectin for outpatient infection treatment, symptom rebound after PAXLOVID treatment, bamlanivimab minimally impacting immune response to vaccination, in-hospital mortality among infection patients, residual viral antigen in patients following infection, usage of Casirvimab/Imdevimab and Remdesivir in infected patients with depleted B-cells, and rheumatic symptoms following infection.

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Download TWiV 910 (29 MB .mp3, 48 min)
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Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

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