TWiV 731: The kids aren’t alright

On a TWiV tetramer, we review the ongoing outbreaks of Ebolavirus disease in DRC and Guinea, evidence that SARS-CoV-2 infections in children are far more prevalent than are being detected, and recent long COVID estimates from the UK.

Hosts: Vincent Racaniello, Rich Condit, Alan Dove, and Brianne Barker

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Weekly Picks 1:35:36

Brianne – Who Would Kidnap a Space Telescope?
Alan – Radio Garden
Rich – Countries with more obesity have had  more covid deaths on average
Vincent – Concord Aerospace

Intro music is by Ronald Jenkees

Send your virology questions and comments to [email protected]

TWiV 730: COVID-19 clinical update #53 with Dr. Daniel Griffin

In COVID-19 clinical update #53, Daniel Griffin reviews underreporting of infections and long term disease in children, a blood test for T cells, results of phase 3 trials for monoclonal antibodies, preliminary findings on an oral antiviral, clinical trial of ivermectin, and recommendations for upcoming gatherings.

Hosts: Daniel Griffin and Vincent Racaniello

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Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to [email protected]

TWiV 729: A floret of spikes with Matt Frieman

Matt Frieman returns to TWiV to discuss the COVID-19 pandemic from the point of view of a coronavirologist, including his work with Novavax on their spike protein-based vaccine.

Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Kathy Spindler, and Brianne Barker

Guest: Matt Frieman

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Weekly Picks 1:43:29

Dickson – Covid-19 deaths per million ranked by average income
Brianne – KFF COVID-19 Vaccine Monitor for Feb 2021 and KFF COVID-19 Vaccine Monitor Dashboard
Rich – The Woman Who Stood Between America and a Generation of ‘Thalidomide Babies’ (wiki)
Kathy – Quadrantid meteor (Quadrantids)
Vincent – Higher Superstition by Paul Gross and Norman Levitt

Intro music is by Ronald Jenkees

Send your virology questions and comments to [email protected]

TWiV 728: Cover your nose and mouse

TWiV notes the passing of Mavis Agbandje-McKenna, and reviews data on maximizing fit for cloth and medical procedure masks, SARS-CoV-2 total and subgenomic viral load in hospitalized patients, and effect of changes in spike protein on efficacy in a mouse model of infection.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Brianne Barker

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Weekly Picks 1:53:57

Dickson – Wild animal photos
Brianne – Greater than COVID
Alan – WHO report on infodemic response
Rich – Reference Guide to the International Space Station
Vincent – 3D Molecular Designs

Listener Picks

Lisbeth – Have the new jab
Karen – Cholera exhibit at Museum of Trades and Crafts

Intro music is by Ronald Jenkees

Send your virology questions and comments to [email protected]

TWiV 727: COVID-19 clinical update #52 with Dr. Daniel Griffin

In COVID-19 clinical update #52, Daniel Griffin reviews differences in attack rates between children and adults, J&J vaccine phase III data, G6PD deficiency and vaccines, NIH halts convalescent plasma trial, dexamethasone in hospitalized patients, data on tocilizumab, and long COVID in children.

Hosts: Daniel Griffin and Vincent Racaniello

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Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to [email protected]

TWiV 726: Molecular animator Janet Iwasa

Janet Iwasa joins TWiV to recount how she became a molecular animator, including a pivot during her Ph.D. thesis research, the value of animations in science, and their latest animation of SARS-CoV-2 entry into cells.

Hosts: Vincent Racaniello, Rich Condit, Brianne Barker and Kathy Spindler

Guest: Janet Iwasa

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  • The Animation Lab 45:04, 1:16:38
  • SARS-CoV-2 animation 51:46
  • Documents for J&J COVID-19 vaccine review (FDA) 1:17:51
    • Phase III data (pdf) 1:18:39
    • Slide presentation of data (pdf) 1:22:08
    • Addendum (pdf) 1:29:41
    • Summary of v-Safe data (pdf) 1:34;50
  • Timestamps by Jolene. Thanks!

Weekly Picks 1:39:07

Brianne – How T cells see SARS-CoV2
Rich – Ice bubbles in Lago Bianco, Switzerland
Kathy – Music in COVID-19 control tents
Vincent – Perseverance runs on processors used in 1990s iMacs

Intro music is by Ronald Jenkees

Send your virology questions and comments to [email protected]

TWiV 725: Eva Harris and Janet Smith clip flavivirus wings

Eva Harris and Janet Smith join TWiV to discuss how an antibody against dengue virus NS1 protein blocks endothelial dysfunction and the potential of treating infections by multiple flaviviruses.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler

Guest: Eva Harris and Janet Smith

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Weekly Picks 1:44:07

Alan – Science Photographer of the Year Awards
Rich – Bar Keeper’s Friend
Kathy – Perseverance secret message and other Easter eggs, 11 million Earthlings’ names, “Name the Rover” essay contest. Sign up to send your name on a future Mars mission.
Vincent – COVID-19 dataset

Listener Picks

Matthew – Remembering the colleagues we lost to COVID-19
Lori – Iceberger

Intro music is by Ronald Jenkees

Send your virology questions and comments to [email protected]

TWiV 724: COVID-19 clinical update #51 with Dr. Daniel Griffin

In COVID-19 clinical update #51, Daniel Griffin reviews use of two masks, effectiveness of testing in nursing homes, updates on vaccines, use of nonsteroidal anti-inflammatory drugs, little effect of vitamin D and remdesivir in clinical studies, and a long COVID research initiative from NIH.

Hosts: Daniel Griffin and Vincent Racaniello

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Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to [email protected]

TWiV 723: COVID-19 palliative care with Ginger Campbell, MD

Ginger Campbell joins TWiV to discuss palliative care for COVID-19 patients, and how to approach the disease from a goals of care perspective.

Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Brianne Barker

Guest: Ginger Campbell, MD

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Weekly Picks 1:34:15

Dickson – Soapbox Gallery
Brianne – Cell Picture Show
Rich – Perseverance Rover’s Descent and Touchdown on Mars (Official NASA Video)
Vincent – Our World in Data (see COVID-19 vaccinations)

Intro music is by Ronald Jenkees

Send your virology questions and comments to [email protected]

TWiV 722: More coronaviruses in the pipeline

The entire TWiV team assembles to discuss resurgence of COVID-19 in Manaus, Brazil, discovery of SARS-CoV-2 related viruses in bats in Southeast Asia, and increased Ct values after administration of mRNA vaccine.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, Kathy Spindler, and Brianne Barker

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Weekly Picks 1:42:45

Dickson – What is the polar vortex?
Brianne – Cloning of the black-footed ferret
Alan – Explaining mRNA vaccines with Star Wars
Rich – Brighton Collaboration (BRAVATO); Ad26 vector template
Kathy – Target public health ads to zipcodes
Vincent – And Then the Gorillas Started Coughing

Listener Pick

Kim – Virus getting the shot (jpg)

Intro music is by Ronald Jenkees

Send your virology questions and comments to [email protected]

The Hosts of TWiV

Vincent Racaniello, Ph.D.


Brianne Barker, Ph.D.


Rich Condit, Ph.D.


Alan Dove, Ph.D.


Daniel Griffin, M.D.,
Ph.D., CTropMed CTH


Angela Mingarelli, DVM


Jolene Ramsey, Ph.D.


Kathy Spindler, Ph.D.


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