The TWiV team returns this week to SARS-CoV-2019 coverage to review the latest epi curves, the fatality rate, furin cleavage site and receptor binding domain in the spike glycoprotein, related CoV recovered from pangolins, evidence that the virus did not escape from a laboratory, and many more questions sent in by listeners.

Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Kathy Spindler

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Download TWiV 588 (91 MB .mp3, 151 min)
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Weekly Science Picks 1:52:40, 2:20:32

Kathy – The deep sea
Rich – World’s oldest message in a bottle
DicksonCoronavirus: A visual guide
Vincent – Recent NSABB meeting Videocasts Day 1 Day 2

Listener Picks

StephenThis podcast will kill you
NevaChina’s surveillance
SophiaWHO online courses

Intro music is by Ronald Jenkees.

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Vincent and Rich return to the University of Texas Medical Branch at Galveston to speak with Dennis Bente, Shannan Rossi, Nikos Vasilakis, and Scott Weaver about their work on viruses transmitted by mosquitoes and ticks.

Hosts: Vincent Racaniello and Rich Condit

Guests: Dennis Bente, Shannan Rossi, Nikos Vasilakis, and Scott Weaver

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Download TWiV 587 (76 MB .mp3, 126 min)
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Intro music is by Ronald Jenkees.

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coronavirus

In this week’s coverage of the coronavirus epidemic, the TWiV team discusses the fatality rate, China’s initial reaction to the outbreak, conspiracy theories, how long the virus remains infectious on surfaces, and evidence for virus in the intestinal tract.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Brianne Barker

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Download TWiV 586 (72 MB .mp3, 119 min)
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Weekly Science Picks 1:49:31

BrianneMutation, Adaptation, and Virus Genomes
Alan – The Comet
Rich – Finding Your Roots: Science Pioneers
DicksonLet’s Fill Our Cities With Taller, Wooden Buildings
VincentTwenty-first century plague by Thomas Abraham

Listener Pick

MarkTracking CoV infections
Sophia Legislative approaches to immunization

Intro music is by Ronald Jenkees.

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The TWiVerers continue their coverage of the new coronavirus outbreak in China, as the number of cases increase dramatically and the virus begins person-to-person transmission in other countries.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, Kathy Spindler, and Brianne Barker

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Download TWiV 585 (71 MB .mp3, 118 min)
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Weekly Science Picks 1:40:55

BriannePandemic
Alan – Educated by Tara Westover
Rich – Star Trek: Picard
DicksonHighest Resolution Image Ever Taken of Surface of the Sun
KathyScientists make vampire bats ‘glow’ to simulate vaccine spread
VincentVirology Lectures 2020

Listener Pick

EdwardVirus snowflake designs
AnthonyMicrobe Hunting Autism to Zika

Intro music is by Ronald Jenkees.

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Coronavirus expert Ralph Baric joins TWiV to explain the virology and epidemiology of the recent zoonotic outbreak spreading across China and overseas.

Coronavirus

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, Kathy Spindler

Guest: Ralph Baric

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Download TWiV 584 (64 MB .mp3, 106 min)
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Weekly Science Picks 1:28:03

Alan – Library plug-in for Firefox or Chrome
Rich – Sounds of the Solar Wind (Parker Solar Probe)
DicksonStunning wildlife photos
KathyIncomplete list of things that blow the minds of intro bio students
VincentMosquito photographs by Alex Wild (and anti-pick)

Listener Pick

JustinYadaYadaYada virus

Intro music is by Ronald Jenkees.

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Vincent and Rich travel to Galveston National Laboratory to speak with Jim LeDuc, Tom Ksiazek, and Bob Tesch about their long careers as virus hunters.

Hosts: Vincent Racaniello and Rich Condit

Guests: Jim LeDuc, Tom Ksiazek, and Bob Tesh

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Download TWiV 583 (51 MB .mp3, 84 min)
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Intro music is by Ronald Jenkees.

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Coronavirus

TWiV provides updates on the new coronavirus causing respiratory disease in China, the current influenza season, and the epidemic of African swine fever, including determination of the three-dimensional structure of the virus particle.

Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Kathy Spindler, and Brianne Barker

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Download TWiV 582 (71 MB .mp3, 118 min)
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Weekly Science Picks 1:45:38

Rich – Mayo Clinic – Ken Burns; Patient Care and Health Information
Dickson – Australia Fires; Insect ecology; Smoke and aerosols
Kathyruncible
VincentWithout a Vaccine, These Are Your Odds

Intro music is by Ronald Jenkees.

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For the first TWiV of 2020 we reveal that microbiome depletion with antibiotics alters the immune response to influenza vaccine, and how successive blood meals facilitate virus dissemination in mosquitoes and transmission potential.

Aedes aegypti

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Kathy Spindler, and Brianne Barker

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Download TWiV 581 (55 MB .mp3, 91 min)
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Weekly Science Picks

Brianne – Retrovirus cookie cutter! (and Phage, Adenovirus, Rabies virus, and Antibody
Alan – “Yah! Yah! Yah!” by Jack London, and the true story it’s based on
DicksonWhy whales are big but not bigger
KathyDual Axis Illusion
VincentThe Fall of the Faculty  by Benjamin Ginsberg

Listener Pick

Suellen – Patient Zero podcast

Intro music is by Ronald Jenkees.

Send your virology questions and comments to twiv@microbe.tv

From the University of Texas at Austin, Vincent and Rich speak with Chris Sullivan about his work on miRNAs encoded in the genomes of polyomaviruses and papillomaviruses, and how an RNA triphosphatase restricts hepatitis C virus replication.

Hosts: Vincent Racaniello and Rich Condit

Guest: Chris Sullivan

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Download TWiV 580 (58 MB .mp3, 96 min)
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Intro music is by Ronald Jenkees.

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Vincent speaks with virologists at the University of Nevada at Reno about their careers and their work on herpesviruses, arboviruses, and the development of diagnostics for infectious diseases.

Host: Vincent Racaniello

Guests: Dave AuCoin, Cyprian Rossetto, Claudia Rückert, and Subhash Verma

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Download TWiV 579 (61 MB .mp3, 101 min)
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Intro music is by Ronald Jenkees.

Send your virology questions and comments to twiv@microbe.tv