Cindy talks with Shane Crotty about his teenage days driving 3 ½ hours every weekend to have his first research experience in marine biology, how that eventually led to studying how vaccines work and how…
Immune 87: When the immune system misbehaves
- January 14, 2025
- Tagged as: Allergies, allergy, antigen presentation, asthma, autoantibodies, autoimmune disease, autoimmunity, B cells, basophils, EBV, IL-33, immune, immunity, immunology, inflammation, invariant chain, Lupus, MHC class II, SLE, Systemic Lupus Erythematosus, T cells, type two inflammation, virus
Immune discusses basophils as regulators of of lung inflammation over space and time, and neoself-antigens as the primary target for autoreactive T cells in human lupus. Hosts: Vincent Racaniello, Cindy Leifer, Steph Langel, and Brianne Barker…
Immune explores the immunological diversity in the upper airway, including memory B and T cells and germinal center B cells, and how chronic infection with Plasmodium parasites leads to development of B cell cancers. Hosts: Vincent…
Immune 73: Big macs
- November 7, 2023
- Tagged as: B cells, immune, immune cells, immunology, macrophage, T cell
Immune reveals the total mass (1.2kg), number (1.8 trillion), and distribution of immune cells in the human body, with macrophages contributing nearly 50% of the total cellular mass.
Kevin joins Immune to discuss his work showing that antibodies against endogenous retroviruses promote immunotherapy of lung cancer.
Immune discusses immunological imprinting, also called original antigenic sin, in the context of infection with SARS-CoV-2 and influenza virus.
Immune discusses the current understanding of immune memory to SARS-CoV-2 infection and COVID-19 vaccines, which supersedes that of any other acute infectious disease.
Cindy, Steph, Brianne, and Vincent review some of their favorite immunology papers of 2022. Hosts: Vincent Racaniello, Cynthia Leifer, Steph Langel, and Brianne Barker Click arrow to playDownload Immune 63 (62 MB .mp3, 103 min)Subscribe (free): Apple Podcasts, Google Podcasts. RSS, emailBecome…
Gabriel Victora joins Immune to review how high affinity antibodies are produced in the germinal centers of secondary lymphoid tissues.
Keke Fairfax joins Immune to discuss the work from her laboratory on understanding how maternal schistosomiasis impairs IL-4 production and B cell expansion in offspring, and modulation of macrophage immunometabolism by helminths.