Immune discusses immunological imprinting, also called original antigenic sin, in the context of infection with SARS-CoV-2 and influenza virus.

Hosts: Vincent Racaniello, Cynthia Leifer, and Steph Langel

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Download Immune 66 (41 MB .mp3, 68 min)
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Music by Steve Neal.
Immune logo image by Blausen Medical

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Immune explains the results of a study which show that in mice, functional T cells respond to vaccination for over 10 years and 51 successive immunizations, exhibiting supernumerary cell division and longevity.

Hosts: Vincent Racaniello, Cynthia Leifer, Steph Langel, and Brianne Barker

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Download Immune 67 (45 MB .mp3, 76 min)
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Music by Steve Neal.
Immune logo image by Blausen Medical

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Immune discusses the current understanding of immune memory to SARS-CoV-2 infection and COVID-19 vaccines, which supersedes that of any other acute infectious disease.

Hosts: Vincent Racaniello, Cynthia Leifer, Steph Langel, and Brianne Barker

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Download Immune 66 (45 MB .mp3, 76 min)
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Music by Steve Neal.
Immune logo image by Blausen Medical

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Cindy, Steph, Brianne, and Vincent do a rapid review of 11 immunology papers, including a wiring diagram for the immune system, group A streptococcus vaccines, systems immunology prediction of vaccines, class switch towards IgG4 after SARS-CoV-2 mRNA vaccination, very bad B cells, monoclonal antibody to two streptococcal M protein epitopes, transcriptional atlas of response to 13 vaccines, impact of SARS-CoV-2 exposure history on T cell and IgG response, neutrophilic inflammation predisposes to RSV infection, commensals avoiding recognition, and continuous germinal center invasion contributes to diversity of immune response.

Hosts: Vincent Racaniello, Cynthia Leifer, Steph Langel, and Brianne Barker

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Download Immune 64 (66 MB .mp3, 110 min)
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Music by Steve Neal.
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Cindy, Steph, Brianne, and Vincent review some of their favorite immunology papers of 2022.

Hosts: Vincent Racaniello, Cynthia Leifer, Steph Langel, and Brianne Barker

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Download Immune 63 (62 MB .mp3, 103 min)
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Music by Steve Neal.
Immune logo image by Blausen Medical

Send your immunology questions and comments to immune@microbe.tv

De’Broski joins immune to reveal his remarkable career path and the research of his laboratory on neuroimmunology and the immune response to parasite infections.

Hosts: Vincent Racaniello, Cynthia Leifer, Steph Langel, and Brianne Barker

Guests De’Broski Herbert

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Download Immune 62 (46 MB .mp3, 77 min)
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Music by Steve Neal.
Immune logo image by Blausen Medical

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From SLB22 on the Island of Hawai’i, Julia and Musa join Immune to reveal their remarkable career paths, and their research on understanding trained innate immunity.

Hosts: Vincent Racaniello, Cynthia Leifer, Steph Langel, and Brianne Barker

Guests: Julia Bohannon and Musa Mhlanga

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Download Immune 61 (46 MB .mp3, 77 min)
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Music by Steve Neal.
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Sumali and Phil join Immune to discuss their approaches to immunology education.

Hosts: Vincent Racaniello, Cynthia Leifer, Steph Langel, and Brianne Barker

Guest: Sumali Pandey and Phil Mixter

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Download Immune 60 (46 MB .mp3, 77 min)
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Music by Steve Neal.
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At Cornell University in Ithaca, NY, Mandy joins Immune to discuss her career and her research on understanding how Th17 cells develop and are influenced to be ‘good’ or ‘bad’ in their function.

Hosts: Vincent Racaniello, Cynthia Leifer, Steph Langel, and Brianne Barker

Guest: Mandy McGeachy

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Download Immune 59 (46 MB .mp3, 77 min)
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Music by Steve Neal.
Immune logo image by Blausen Medical

Send your immunology questions and comments to immune@microbe.tv