ImmuneImmuneImmuneImmune

Tag: Tlr9

  • Immune

Immune 50: Red blood cells are immune sentinels

  • November 11, 2021
  • Tagged as: anemia, COVID-19, DNA, immune, immunology, innate immunity, macrophage, red blood cell, sepsis, Tlr9

Immune reviews evidence that toll-like receptor 9 on the surface of red blood cells binds DNA, leading to uptake by macrophages and innate immune activation.

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  • Immune

Immune 17: Feed a macrophage, starve a tumor

  • February 13, 2019
  • Tagged as: cancer, CD47, CpG, glycolysis, immune, immunology, Krebs cycle, Tlr9, tumor

The immunophiles explain how metabolic rewiring of macrophages by CpG promotes clearance of cancer cells.

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