TWiV 117: The Panic Virus with Seth Mnookin

panic virusHosts: Vincent Racaniello, Rich Condit, and Seth Mnookin

Vincent and Rich converse with Seth Mnookin, author of The Panic Virus, about vaccines, autism, thimerosal, and a contagion of human unreason run wild.

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Rich and Vincent – The Panic Virus by Seth Mnookin

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TWiV 116: Cocaine, colonies, and chickens

<p”>hive and feeding bottlesHosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Dickson, Alan, and Rich review an adenovirus-based vaccine strategy against drug addiction, a field trial of RNAi to prevent Israeli acute paralysis virus infection in honeybees, and suppression of avian influenza transmission in transgenic chickens.

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Dickson – Brian Deer’s investigation of Andrew Wakefield
Rich – Photographic periodic table of the elements
Alan – Year of the bat (site one and site two)
Vincent – EteRNA (NY Times article)

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TWiV 115: Color me infected

brainbow pseudorabies virusHosts: Vincent Racaniello, Alan Dove, Rich Condit, and Marc Pelletier

Vincent, Alan, Rich and Marc discuss the finding that a limited number of incoming herpesviral genomes can replicate and express in a cell, and controlling viral replication in Aedes aegypti with a Wolbachia symbiont.

Click the arrow above to play, or right click to download TWiV #115 (84 MB .mp3, 117 minutes).

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Marc – Homebrew bioreactor (photo, movie) – culture bottle and drive, oil-free vacuum pumps
Rich – Logitech Harmony Universal Remote
Alan – H.M.S. Challenger Reports
Vincent – Sequence of the strawberry genome and blog post by lead author

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TWiV 114: Ten out of ’10

vaccinia plaqueHosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich revisit ten compelling virology stories of 2010.

Click the arrow above to play, or right click to download TWiV #114 (64 MB .mp3, 88 minutes).

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Ten virology stories of 2010:

  1. XMRV, CFS, and prostate cancer (TWiV 113, 99, 98, 94, 89, 76, 70, 65)
  2. The ongoing saga of polio eradication (TWiV 110, 79)
  3. Viruses interact with the miRNA/siRNA system (TWiV 108, 72)
  4. Endogenous viruses – retro and beyond (TWiV 105, 91, 88, 65)
  5. Dengue virus progress and new outbreak (TWiV 111, 95, 82)
  6. Colony collapse disorder (TWiV 104)
  7. David Baltimore (TWiV 100)
  8. Ode to a plaque (TWiV 68)
  9. Vaccine contamination with circovirus (TWiV 86, 77, 75)
  10. Universal influenza vaccines (TWiV 107)

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Rich – Elementary schoolchildren publish a science paper (original article and editorial with video) – thanks Kathy!
Alan – White-nose syndrome blog
Vincent – Headway, headlines and healthy skepticism

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TWiV 113: Alan Rein on XMRV

rich conditHosts: Vincent Racaniello, Alan Dove, Rich Condit, and Alan Rein

Vincent, Alan, and Rich discuss the retrovirus XMRV with retrovirologist Alan Rein of the National Cancer Institute.

Click the arrow above to play, or right-click to download TWiV #113 (55 MB .mp3, 76 minutes).

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Rich – Word Lens
Alan – Tetenal Press Kit
Vincent – In the pipeline and Things I won’t work with by Derek Lowe

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TWiV 112: Creating a killer poxvirus

dickson despommierHosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich review the making of a virulent poxvirus by insertion of the gene encoding IL-4, and severe 2009 H1N1 influenza due to pathogenic immune complexes.

Click the arrow above to play, or right-click to download TWiV #112 (71 MB .mp3, 98 minutes). To download, right-click or control-click on the link, then select save as.

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Rich – The Scientist’s Top 10 Innovations 2010
Alan – Avian Vocalizations Center
Vincent – Microbial soap from Cleaner Science (thanks, Nadia!)

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TWiV 111: Live at Florida Gulf Coast University

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Ed Fussell, Andrea Leal, and Amy Sargent

The TWiV crew meets with members of the Florida Keys Mosquito Control District at Florida Gulf Coast University to discuss dengue in Florida and how to control it.



Click the arrow to play, or right-click to download TWiV #111 (76 MB .mp3, 105 minutes).

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Rich – At the Bench, A Laboratory Navigator by Kathy Barker
Alan – DEEP Indonesia Underwater Photo Contest 2010 Winners
Vincent – HHMI resources for early-career scientists

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TWiV at FGCU

TWiV 110: CSI virology

Alan DoveHosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Rich Condit

Vincent, Alan, Rich, and Dickson discuss bacteria that can utilize arsenic in place of phosphorus, the passing of Frank Fenner, polio outbreak in The Congo, solving criminal cases of HIV transmission, and classifying viruses by capsid structure.

Click the arrow to play, or right-click to download TWiV #110 (68 MB .mp3, 93 minutes).

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Dickson – CDC’s West Nile virus case count for 2010
Rich – The red bees of Red Hook
Alan – Arsenic-based life at XKCD
Vincent – PLoS iPad app

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TWiV 109: Virologia en México

Hosts: Vincent Racaniello, Rosa Maria del Angel, and Ana Lorena Gutiérrez

Vincent visits Mexico City and speaks with Rosa Maria del Angel and Ana Lorena Gutiérrez about virology in Mexico, and their work on dengue and caliciviruses.

Click the arrow above to play, or right-click to download TWiV #109 (58 MB .mp3, 80 minutes).

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Lorena – Caliciviruses by Hansman, Jiang, and Green
Vincent – Insights into dengue virus genome replication by Alcaraz-Estrada, Yocupicio, and del Angel

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TWiV 108: Barking up the right Tre

twivHosts: Vincent Racaniello, Alan Dove, Rich Condit, and Saul Silverstein

Vincent, Alan, Rich, and Saul review the evolution of HIV-1 specific recombinases, and down-regulation of a host microRNA by a viral noncoding RNA.

Click the arrow above to play, or right-click to download TWiV #108 (64 MB .mp3, 89 minutes). To download, right-click or control-click on the link, then select save as.

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Weekly Science Picks

Rich – Where cinema and biology meet
Alan – Qiagen iApp
Vincent – Ask a biologist

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