Daniel Griffin provides a clinical update on COVID-19, then Sabra Klein joins us to discuss the effect of sex, gender, and age on viral infectious disease, including COVID-19.
Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, Kathy Spindler and Brianne Barker
Guests: Daniel Griffin, Chuck Knirsch, and Sabra Klein
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Links for this episode
- SeXX matters in infectious disease pathogenesis (PLoS Path)
- Sex and gender impact immune responses to vaccines (Physiol)
- Testosterone and disease severity in mice (Cell Immunol) 52:36
- Age-associated effects on impact of sex steroids on vaccine responses (NPJ Vaccines) 1:17:07
- Evolution of greater humoral immunity in females (Curr Opin Physiol)
- Impact of sex and gender on COVID-19 (Biol Sex Diff) 1:40:41
- COVID-19 trials should include sex as variable (J Clin Inves) 1:42:56
- Global Health 50/50 1:30:06
- Timestamps by Jolene. Thanks!
Intro music is by Ronald Jenkees
Send your virology questions and comments to firstname.lastname@example.org
That’s called “pair bonding” species vs. “tournament species.” Sapolsky points out it’s experimentally associated, in primates with the D2 dopamine receptor *type* (IIRC – those receptors in the Nucleus Accumbens and Ventral Tegmental Areas). https://youtu.be/LOY3QH_jOtE?list=PL150326949691B199
At least voles were shown to be experimentally adjustable between being pair bonding and tournament.
Happy Belated Birthday Prof Despommier!!!!! Continued great health. Live long and prosper!
It feels like this paper from John Hussman does not take into account the theme of your lecture regarding gender and sex and immune responses?
Scott Campbell MD, MPH
Department of Emergency Medicine
Kaiser San Francisco