Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Rich Condit

Vincent, Dickson, Alan, and Rich answer listener questions about poliovirus, social media, dengue, influenza, evolution, gel filtration, and much more.

Click the arrow above to play, or right-click to download TWiV #107 (68 MB .mp3, 94 minutes).

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Weekly Science Picks

Rich – Protein Synthesis: An epic on the cellular level
Dickson – The Patchwork Mouse by Joseph R. Hixson
Alan – Bill Hammack’s engineering videos
Vincent –
Visual Science (thanks, Svetlana)

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Hosts: Vincent Racaniello, Dickson Despommier, and Rich Condit

Vincent, Dickson, and Rich continue Virology 101 with a second installment of their discussion of how viruses with DNA genomes replicate their genetic information.



Click the arrow above to play, or right-click to download TWiV #106 (69 MB .mp3, 95 minutes)

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Weekly Science Picks

Rich – Google Health
Dickson – The Neandertal genome
Vincent – Lab techniques videos (thanks, Erik!)

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the 5prime end problem

Hosts: Vincent Racaniello, Dickson DespommierAlan Dove, and Rich Condit

The entire TWiV family reviews the latest ideas about colony collapse disorder of honeybees, and resurgence of monkeypox in Africa.

Click the arrow above to play, or right-click to download TWiV #104 (70 MB .mp3, 97 minutes)

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Weekly Science Picks

Dickson – Four Fish by Paul Greenberg
Alan – Nikon Small World contest, 2010 winners
Rich – Encyclopedia of Life
Vincent –
First all-digital science textbook will be free (thanks, @windsurfer)

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Hosts: Vincent Racaniello, Alan Dove, and LJ Tan

Vincent and Alan discuss influenza vaccines with LJ Tan of the American Medical Association.

Click the arrow above to play, or right-click to download TWiV #103 (56 MB .mp3, 77 minutes)

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Weekly Science Picks

Alan – BioGene, an iApp
Vincent – The Vertical Farm by Dickson Despommier

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Hosts: Vincent Racaniello, Andrew BakerKarl-Klaus ConzelmannPeter Palese, and Katharina Eisenächer

A conversation about the RNA sensor RIG-I, adenovirus gene therapy, a universal influenza vaccine, and rabies virus, recorded in Munich, Germany at the SFB455 symposium ‘Viral offense and immune defense’.



Click the arrow above to play, or right-click to download TWiV #102 (67 MB .mp3, 95 minutes)

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Weekly Science Picks

Katharina – Deutsches Museum
Vincent – HHMI holiday lectures on science (thanks Judi!)

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Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Dickson Despommier, and Hamish Young

Vincent, Alan, Rich, Dickson, and Hamish review the three-dimensional structure of adenovirus, and the role of adenovirus type 36 in obesity.

Click the arrow above to play, or right-click to download TWiV #101 (55 MB .mp3, 76 minutes)

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Weekly Science Picks

Alan – National Geographic’s Best Environmental Photographs of 2010
Rich –
Richard Feynman lecture: The pleasure of finding things out
Vincent – Summary of the First International XMRV Workshop (pdf)

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Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and David Baltimore

Vincent, Alan, and Rich celebrate the 100th episode of TWiV by talking about viruses with Nobel Laureate David Baltimore.

Click the arrow above to play, or right-click to download TWiV #100 (68 MB .mp3, 94 minutes)

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Weekly Science Picks

Alan – TimeTree
Rich –
The neurons that shaped civilization
Vincent – Ahead of the Curve: David Baltimore’s Life in Science by Shane Crotty

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Host: Vincent Racaniello

On episode 99 of the podcast This Week in Virology, Vincent tours the 50th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) in Boston, speaking with exhibitors and visitors, including Professors Derek Smith, Michael Schmidt, Frederick Hayden, and Myra McClure.

Many thanks to Chris Condayan and Ray Ortega of the American Society for Microbiology for recording and editing this episode.



Click the arrow above to play, or right-click to download TWiV #99 (45 MB .mp3, 62 minutes)

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Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich review the finding of murine leukemia virus-related sequences in the blood of CFS patients and healthy donors, laboratory inventories for wild poliovirus containment, weaving high-performance viral batteries into fabric for the military, and a case of human rabies in Indiana.

Click the arrow above to play, or right-click to download TWiV #98 (58 MB .mp3, 80 minutes)

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Weekly Science Picks

Alan – NCBI ROFL
Rich –
The Great Bridge by David McCullough
Vincent – Dr. Rous’ Prize-Winning Chicken

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Hosts: Vincent Racaniello, Peter Sarnow, and Bert Semler

During a trip to California, Vincent visited Peter Sarnow and Bert Semler and spoke with them about their work on internal ribosome entry, and the requirement for a cellular microRNA for hepatitis C virus replication.

Click the arrow above to play, or right-click to download TWiV #97 (66 MB .mp3, 91 minutes)

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  • Eukaryotic mRNAs that might contain an IRES (PNAS)
  • Modulation of HCV RNA abundance by a liver-specific microRNA (Science)
  • Viral small RNAs (PLoS Pathogens)
  • Bridging IRES elements to the translation apparatus (Biochim Biophys Acta)
  • A nucleo-cytoplasmic SR protein functions in viral IRES mediated translation (EMBO J)
  • Nuclear vs cytoplasmic routes to IRES mediated translation (Trends in Microbiology)
  • Letter read on TWiV 97

Send your virology questions and comments to twiv@microbe.tv.