Hosts: Vincent Racaniello, Alan Dove, and Matthew Frieman

Vincent, Alan, and Matt review contamination of Rotarix with circovirus DNA, antigenic similarity between 1918 and 2009 H1N1 influenza, a collection of rabies reports, and chicken pox mistaken for smallpox in Uganda.

This episode is sponsored by Data Robotics Inc.

Click the arrow above to play, or right-click to download TWiV #75 (57 MB .mp3, 79 minutes)

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Matt Bitesize Bio
Alan Free printable graph paper (see also doane paper)
Vincent Avian Flu Diary

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Hosts: Vincent Racaniello and Adolfo Garcia-Sastre

Vincent speaks with Adolfo Garcia-Sastre about the origin, pathogenesis, and prevention of the 2009 pandemic influenza H1N1 virus.

This episode is sponsored by Data Robotics Inc.

Click the arrow above to play, or right-click to download TWiV #74 (34 MB .mp3, 47 minutes)

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Hosts: Vincent Racaniello, Dickson Despommier, and Rich Condit

Vincent, Dickson, and Rich discuss multipotent progenitor bone marrow cells as a reservoir of HIV-1, integration of HHV-6 into telomeres, and dispersal of West Nile virus across the US by mosquitoes.

This episode is sponsored by Data Robotics Inc.

Click the arrow above to play, or right-click to download TWiV #73 (63 MB .mp3, 87 minutes)

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Dickson Whole-Genome Sequencing in a Patient with Charcot–Marie–Tooth Neuropathy (NEJM and NY Times)
Rich Invisible Frontiers: The Race to Synthesize a Human Gene by Stephen Hall
Vincent Conference on Retroviruses and Opportunistic Infections –  videocasts

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Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Rich Condit

This week the TWiV team explains CRISPR/Cas, the immune system of bacteria and archaea, how novel viruses are discovered by deep sequencing of small RNAs, and the relationship between dry weather and outbreaks of West Nile virus infection.

This episode is sponsored by Data Robotics Inc.

Click the arrow above to play, or right-click to download TWiV #72 (62 MB .mp3, 85 minutes)

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Dickson Scientist as Chef by Dickson Despommier (pdf)
Alan Networked Organisms and Habitats (NOAH) iPhone app
Rich Never Cry Wolf by Farley Mowat
Vincent The Dish

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Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Rich Condit

Vincent, Dickson, Alan, and Rich answer listener questions about maternal infection and fetal injury, viral gene therapy, eyeglasses and influenza, filtering prions from blood, eradication of rinderpest, Tamiflu resistance of H1N1 influenza, bacteriophages and the human microbiome, H1N1 vaccine recalls, human tumor viruses, RNA interference, and junk DNA.

This episode is sponsored by Data Robotics Inc.

Click the arrow above to play, or right-click to download TWiV #71 (63 MB .mp3, 88 minutes)

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Dickson and Alan NSF/AAAS Science and Engineering Visualization Challenge
Rich Foundation by Issac Asimov
Vincent Natural Obsessions by Natalie Angier

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Hosts: Vincent Racaniello, Dickson Despommier, and Alan Dove

Vincent, Dickson, and Alan consider a broad spectrum antiviral against enveloped viruses, how a plant virus induces chemical signals in the host to maximize its spread, a new way to preserve viral vaccines at tropical temperatures, and the continuing story of XMRV and chronic fatigue syndrome.

This episode is sponsored by Data Robotics Inc.

Click the arrow above to play, or right-click to download TWiV #70 (56 MB .mp3, 77 minutes)

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Dickson Chemical Ecology – edited by Thomas Eisner and Jerrold Meinwald
Alan Scripps Center for Mass Spectrometry
Vincent Folding@home (thanks Jesper!)

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Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich review recent outbreaks of mumps in the UK, US, and Israel, protection of mice against 2009 H1N1 influenza A virus by 1918-like and classical swine H1N1 vaccines, and a virus-like particle vaccine for chikungunya virus.

This episode is sponsored by Data Robotics Inc.

Click the arrow above to play, or right-click to download TWiV #69 (59 MB .mp3, 82 minutes)

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Rich John Moran Florida Nature Photography
Alan Periodic Table of Videos
Vincent The Protein Databank Educational Resources

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Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich are enthralled by movies of vaccinia virus plaque formation, then consider how repulsion of superinfection virions leads to rapid virus spread, and a therapeutic prostate cancer vaccine.

This episode is sponsored by Data Robotics Inc. Use the promotion code VINCENT to receive $50 off a Drobo or $100 off a Drobo S.

Win a free Drobo S! Contest rules here.

Click the arrow above to play, or right-click to download TWiV #68 (58 MB .mp3, 80 minutes)

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Rich Foundations of Virology – PowerPoint by Frederick A. Murphy (bio/interview pdf)
Alan Spoonful of Medicine – Nature Medicine blog
Vincent The Feynman Lectures (thanks Ilya!)

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Hosts: Vincent Racaniello, Alan Dove, and Marc Pelletier

Vincent, Alan, and Marc talk about chronic wasting disease of deer caused by prions, blocking the semen-derived enhancer of HIV infection with surfen, and making green transgenic rabbits using a lentiviral vector.

This episode is sponsored by Data Robotics Inc.

Click the arrow above to play, or right-click to download TWiV #67 (64 MB .mp3, 88 minutes)

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Marc Association of Science-Technology Centers Passport Program
Alan Zooniverse
Vincent Grand Rounds at the Mailman School of Public Health

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Hosts: Vincent Racaniello and Dickson Despommier

Vincent and Dickson continue virology 101 with a discussion of information flow from RNA to DNA, a process known as reverse transcription, which occurs in cells infected with retroviruses, hepatitis B virus, cauliflower mosaic virus, foamy viruses, and even in uninfected cells.

This episode is sponsored by Data Robotics Inc.



Click the arrow above to play, or right-click to download TWiV #66 (50 MB .mp3, 68 minutes)

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Vincent Joint UN Programme on HIV/AIDS

Send your virology questions and comments to twiv@microbe.tv.