Patricia writes: Hello Dr Griffin, One topic I have not seen anywhere is drug metabolism. I seem to be a poor metabolizer of drugs. I’ve been like this my entire life. Even Aspercreme can put…
Andrew Macadam writes: Dear Vincent, What a nice surprise to hear you all talking about nOPV2 on TWiV! Wonderful discussion, thanks for your kind remarks about our paper, and for your supportive review (the paper…
Mathilde writes: Dear Vincent and colleagues, I often listen to TWIV and always appreciate the discussions. I was very happy to see that one of our papers was discussed in TWIV 753! I am the…
Pete writes: Daniel, I have just sent some money to a friend in India for oxygen – 500USD for a cylinder and 200USD for a fill, that would probably help 2 people. I’m thinking mAb’s…
TWiV discusses the finding that the envelope (E) protein of SARS-CoV-2 is sensed by toll-like receptor 2 on cells, leading to the production of inflammatory cytokines that cause damage to cells and tissues in COVID-19.
John writes: Hi Twiv! I’m wondering if I can make a request. My wife’s name is Amy and she is one of your biggest fans. She’s a physician and listens to your podcast religiously. She…
Clarissa writes: Hi Rich, I listened to TWIV yesterday. Very good discussion and explanations. Thank you. The discussions are still ongoing here because now Russia decides to go forward with a one-dose vaccine, Sputnik light….
Anon writes:Hello TWIV: My father was recently diagnosed with plasmablastic lymphoma. He received his first dose of the Moderna COVID vaccine three weeks before his diagnosis. I know that some people have had a lymphatic…
TWiV examines the claim by Brazil’s ANVISA that the Sputnik vaccine contains replication-competent adenovirus, and a role for the furin cleavage site in SARS-CoV-2 spike for efficient reproduction in the respiratory tract, evasion of antiviral IFITM proteins, and transmission in ferrets.
The TWiVmeisters discuss how copy-back defective viral genomes might modulate the clinical outcome of respiratory syncytial virus infection, and detection of antibodies to henipa- and filo-like viruses in Trinidad bats.
The Hosts of TWiV
Vincent Racaniello, Ph.D.
Dickson D.
Despommier, Ph.D.
Alan Dove, Ph.D.
Daniel Griffin, M.D.,
Ph.D., CTropMed CTH
Jolene Ramsey, Ph.D.