ImmuneImmuneImmuneImmune
  • About IMMUNE

Tag: immunology

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Immune 8: Staying warm with γδ T cells

  • May 25, 2018
  • Tagged as: homeostasis, IL-17A, immune, immunology, T cells, thermogenesis, γδT cells

The Immune team reveals how γδT cells that synthesize interleukin-17A regulate adipose regulatory T cell homeostasis and thermogenesis.

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  • Immune

Immune 7: Contradictory complements in Alzheimer’s Disease

  • April 18, 2018
  • Tagged as: AD, Alzheimer's disease, C1q, complement, immune, immunology, MAC, mouse model, synapse, synaptic pruning

The Immune hosts discuss how the complement system functions, and its role in early synapse loss in a mouse model of Alzheimer’s disease.

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  • Immune

Immune 6: Potent antiviral antibodies without somatic mutation

  • March 16, 2018
  • Tagged as: antibody, B cell, epitope, F protein, IgG, IgM, immune, immune response, immunology, lymph node, respiratory syncytial virus, somatic hypermutation, V(D)J recombination, vaccine enhanced disease

The Immune hosts explain how antibody molecules mature, then discuss the finding in infants of potent neutralizing antibodies against respiratory syncytial virus without somatic hypermutation.

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  • Immune

Immune 5: Mother knows best about food allergies

  • February 22, 2018
  • Tagged as: allergic reactions, atopy, breast milk, food allergy, immune, immunology, mucosal defenses, mucosal immunology, tolerance

The ImmuoModulators provide a primer on mucosal defenses, and explain how sensitizing female mice to food allergens prevents allergic reactions in their offspring.

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  • Immune

Immune 4: Putting the immunotherapy CAR T before the cancer

  • January 23, 2018
  • Tagged as: B cell, cancer immunotherapy, CAR T cell, checkpoint inhibitor, chimeric antigen receptor, CTLA4, immune, immunology, immunotherapy, oncology, PD-1, T cell, Tisagenlecleucel

The immu-knowledge-ists deconstruct the holy grail of oncologists, cancer immunotherapy, and the exciting development of CAR T cells and how they work.

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  • Immune

Immune 3: Two epitopes, four serotypes, and a partridge in a pear tree

  • December 16, 2017
  • Tagged as: ADE, antibody dependent enhancement, antibody therapy, bispecific antibody, dengue virus, dengvaxia, immune, immunology, monoclonal antibody, passive vaccine, Zika virus

Cindy, Steph, and Vincent discuss recent problems with dengue virus vaccine, and a bi-specific monoclonal antibody against Zika virus.

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  • Immune

Immune 2: Lymphocytes after dark

  • November 25, 2017
  • Tagged as: 24 hour clock, adaptive immunity, B cell, circadian, clock gene, immune, immunology, lymph, lymph node, lymphocyte, T cell

Cindy, Steph, and Vincent reveal that lymphocyte trafficking through lymph nodes and lymph is circadian – it is dependent on the time of day.

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  • Immune

Immune 1: Some like it hot

  • November 1, 2017
  • Tagged as: atherosclerosis, bone marrow, fever, immune, immunology, macrophage, monocytes, thermogenesis, thermoregulation, UPC1

Cindy, Steph, and Vincent launch a new podcast, Immune, and talk about how warm temperature protects against atherosclerosis by regulating monocyte migration into the blood.

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The Hosts of IMMUNE

Brianne Barker, Ph.D.


Stephanie Langel, Ph.D.


Cindy Leifer, Ph.D.


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