The TWiVerati discuss the FDA Advisory Committee deliberation on the anti-poxvirus drug tecovirimat, and immune cells in gut-associated lymphoid tissue as the major target during acute murine norovirus infection.
The Masters of the TWiXome review the development of sensitive, portable, and field-based viral diagnostics using the CRISPR-Cas system.
The TWiVome deconstructs the evolutionary history of RNA viruses, and immune promotion of murine norovirus pathogenesis by replication in intestinal tuft cells.
From the TWiV team, human cowpox infection possibly acquired from a pet cat, and a new giant mimivirus of green algae with genes encoding enzymes of fermentation.
Vincent visits Sandra Urdaneta-Hartmann at Drexel University College of Medicine in Philadelphia to talk about the development of the mobile video game ‘CD4 Hunter’.
The TWiV team reveals that recent mumps virus outbreaks in the US are due to waning vaccine efficacy, and an intranasally delivered small interfering RNA that controls West Nile infection in the brain.
At the Medical College of Wisconsin, Vincent talks with current and former members of the Department of Microbiology and Immunology about their work and their careers.
Sean Whelan returns to TWiV to speak with Vincent about using haploid cell lines to identify genes encoding cell receptors for viruses, including Ebolavirus, Lassa virus, and more.
The TWiV posse considers viral insulin-like peptides encoded in fish genomes, and antiviral immunity in insects by production of viral DNA from defective genomes of RNA viruses.
The TWiVumvirate discuss the giant Tupanvirus, with the longest tail in the known virosphere, and dampened STING dependent interferon activation in bats.
The Hosts of TWiV
Vincent Racaniello, Ph.D.
Brianne Barker, Ph.D.
Rich Condit, Ph.D.
Alan Dove, Ph.D.
Daniel Griffin, M.D.,
Ph.D., CTropMed CTH
Angela Mingarelli, DVM
Jolene Ramsey, Ph.D.
Kathy Spindler, Ph.D.