TWiV discusses secret anti-vax campaign run by Pentagon to undermine China during pandemic, NY governor’s subways mask ban proposal, Colorado bat facility sparks outbreak fears, House budget billls suggest ban on gain of function research, evolution of STAT2 resistance to flavivirus NS5, and brainwide silencing of prion protein by AAV-mediated delivery of an epigenetic editor.
TWiV reviews the FDA decision to update COVID-19 vaccine boosters in the fall, the meaning of fatigue with respect to long COVID, and a skin volatile induced by flavivirus reproduction that attracts mosquitoes to the infected host.
Eva Harris and Janet Smith join TWiV to discuss how an antibody against dengue virus NS1 protein blocks endothelial dysfunction and the potential of treating infections by multiple flaviviruses.
From the 2020 online meeting of the American Society for Tropical Medicine and Hygiene, Vincent speaks with Jonathan Auguste, Carol Blair, Desiree LaBeaud, Louis Lambrechts, and Mauricio Nogueira about their careers and their research on arthropod-borne viruses.
From DukeNUS Medical School, Vincent speaks with Ashley, Sheemei, Eng Eong and Dahai about their careers and their research on flaviviruses and sensing of viral RNA.
Ralph Baric, Mark Heise and Nat Moorman discuss their non-profit initiative READDI, Rapidly Emerging Antiviral Drug Discovery Initiative, to start making drugs now for the next pandemic virus.
Vincent speaks with Félix Rey about his career and his work on solving structures of a variety of viruses and the insights learned about viral membrane fusion and antibody-mediated neutralization.
Vincent travels to the University at Albany to speak with Cara, Rachel, and Alex about their careers and their work on stress granules, epitranscriptomics, and arboviruses.
The TWiV team discuss the use of quantum dots to study uncoating of influenza virus in real time, and induction of endothelial dysfunction by flavivirus NS1 proteins in a tissue-specific manner.
The TWiV team summarizes the discovery of Sin Nombre virus, and presents evidence that neurotropic flaviviruses can cause intestinal dysmotility syndromes after systemic infection of mice.