From DukeNUS Medical School, Vincent speaks with Ashley, Sheemei, Eng Eong and Dahai about their careers and their research on flaviviruses and sensing of viral RNA.
Host: Vincent Racaniello
Guests: Sheemei Lok, Dahai Luo, Eng Eong Ooi, and Ashley St. John
Click arrow to play
Download TWiV 633 (56 MB .mp3, 93 min)
Subscribe (free): iTunes, Google Podcasts, RSS, email
Become a patron of TWiV!
Links for this episode
- Dengue virus and endothelial permeability (J Clin Invest) 25:04, 36:30
- Dengue virus morphological switch (PLoS Path) 49:27
- Symptomatic yellow fever vaccine infections (Nat Med) 1:03:28
- RNA recognition by RIG-I and MDA5 (Nucl Acids Res) 1:17:34
- Timestamps by Jolene. Thanks!
Intro music is by Ronald Jenkees
Send your virology questions and comments to twiv@microbe.tv
Thanks Vincent..excellent podcast.
Beautiful minds and cutting edge science..
Wow…they are finding with Covid-19 issues with angiotensin 1 or 2 can lead to lots of ROS in the endothelium and an increase in Von Willebrand factor elongation…thus leading to clotting…which is what is making this disease so much than many other respiratory illnesses. It sounds like this guy already figured this out ahead of time. Are there any studies where blood is taken when the sample is collected for the PCR so they can measure if stress level at time of infection correlates with severity of disease?