Eva Harris and Janet Smith join TWiV to discuss how an antibody against dengue virus NS1 protein blocks endothelial dysfunction and the potential of treating infections by multiple flaviviruses.
From DukeNUS Medical School, Vincent speaks with Ashley, Sheemei, Eng Eong and Dahai about their careers and their research on flaviviruses and sensing of viral RNA.
From the Environmental Health Institute in Singapore, Vincent speaks with Director Lee Ching Ng about their work to control viral infectious diseases, including the controlled release of mosquitoes containing Wolbachia endosymbionts to inhibit viral transmission.
Ralph Baric, Mark Heise and Nat Moorman discuss their non-profit initiative READDI, Rapidly Emerging Antiviral Drug Discovery Initiative, to start making drugs now for the next pandemic virus.
Vincent and Rich return to the University of Texas Medical Branch at Galveston to speak with Dennis Bente, Shannan Rossi, Nikos Vasilakis, and Scott Weaver about their work on viruses transmitted by mosquitoes and ticks.
Vincent speaks with Félix Rey about his career and his work on solving structures of a variety of viruses and the insights learned about viral membrane fusion and antibody-mediated neutralization.
The TWiV pro-vaxxers reveal viruses that infect endangered wild salmon, and how iron in host serum modulates dengue virus acquisition by mosquitoes.
Team TWiV reveals DNA polymerases that do not require a primer, and packaging of hepatitis delta virus by the envelope glycoproteins of diverse viruses.
The TWiV team discuss the use of quantum dots to study uncoating of influenza virus in real time, and induction of endothelial dysfunction by flavivirus NS1 proteins in a tissue-specific manner.
The TWiVome explores induction of antiviral responses by repeating patterns of capsids, and a fungus in the mosquito gut that aids dengue virus replication.