Alessandro Sette joins TWiV to discuss the role of T cells in COVID-19, the finding that amino acid changes in SARS-CoV-2 variants of concern have a negligible impact on T cell reactivity in convalescent patients and vaccinees, and whether a next generation vaccine should include more viral proteins than spike.

Allison writes: Dear most highly esteemed TWiV team! Like your other avid fans, I have been listening with great interest for months. I first found you after I tested positive with SARS-CoV-2 on Halloween 2020….

John writes: I love TWIV – and listen every week. And as an ID doc that does mostly research – I also appreciate the COVID clinical updates.  So glad to help out Dr. Dan Griffin…

Eric writes: Hi TWiVers! Me again, just an astronomer who has been listening to TWiV since last February. How time flies. During TWiV 731, you folks discussed the orbits of the James Webb Space Telescope…

Martha writes: Hello Dr. Griffin, I love your podcasts! I have a question regarding age and Covid vaccine dose. Does it seem that the elderly population might need a larger dose of the vaccine than…

Charles writes: As you look through NPR this morning at the Peter Daszak article: https://www.npr.org/sections/goatsandsoda/2021/03/15/977527808/who-points-to-wildlife-farms-in-southwest-china-as-likely-source-of-pandemic Don’t miss the vector article: https://www.npr.org/2021/03/16/976598336/scientists-find-new-invasive-mosquito-species-in-florida Normally I would say enjoy the read, but I cannot enjoy reading about a…

On a TWiV tetramer, we review the ongoing outbreaks of Ebolavirus disease in DRC and Guinea, evidence that SARS-CoV-2 infections in children are far more prevalent than are being detected, and recent long COVID estimates from the UK.

Martin writes: Dickson’s sandman rendition was brilliant. A cappella isn’t easy. Who knew vertical gardens and Victor Borge quality and style entertainment. Pearls before swine is Mathew 7:6  isn’t it.  Another brilliant ep., keep ’em …