On this episode, FDA EUA for Pfizer mRNA vaccine, efficacy of AstraZeneca ChAdOx1 COVID-19 vaccine, and an orally administered drug that blocks SARS-CoV-2 transmission in ferrets.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Brianne Barker

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Weekly Science Picks 1:42:53

Dickson2020 In Photos: A Year Like No Other
BrianneCooking for Geeks
AlanOn Food and Cooking
RichNASA Artemis (Wiki)
VincentThe virus, the bats, and us

Intro music is by Ronald Jenkees

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Daniel Griffin provides his weekly clinical report on COVID-19, including the anticipated EUA for the Pfizer mRNA vaccine, mitigation strategies in early care and education settings, expressive aphasia, and much more.

Hosts: Daniel Griffin and Vincent Racaniello

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Download TWiV 692 (23 MB .mp3, 38 min)
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Intro music is by Ronald Jenkees

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SciArtist Laura Splan joins TWiV to reveal her transdisciplinary work that intersects science, technology, design and culture, then we discuss an inverse correlation between mumps virus antibodies induced by MMR vaccine and COVID-19 severity, and whether ivermectin is indicated for treatment of COVID-19.

Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker

Guest: Laura Splan

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Weekly Picks 1:51:36

Brianne – Patterns for Virus snowflakes
Kathy – 2020 Nobel Prize lectures (hepatitis C) (link to all and concert) Historical review by Harvey Alter
RichNew Data Confirm 2020 SO is Upper Centaur Rocket Booster from 1960’s (Wiki)
VincentThe Right Stuff

Listener Pick

MiikaelTiny tweak behind COVID-19 vaccines

Intro music is by Ronald Jenkees

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TWiV reviews the difficulties in predicting species susceptibility to SARS-CoV-2 infection by only examining the ACE2 protein, and the olfactory mucosa as a portal of entry into the central nervous system in COVID-19 patients.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Rich Condit

Guest: Amy Rosenfeld

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Weekly Science Picks 1:38:52

DicksonNational Geographic best animal photos of 2020
AmyAmerican Contagions: Epidemics and the law from Smallpox to COVID-19 by John Fabian Witt
AlanHamSCI citizen science organization
RichDeepMind’s AI makes gigantic leap in solving protein structures
VincentArmy Ants: Nature’s Ultimate Social Hunters by Daniel Kronauer

Intro music is by Ronald Jenkees

Send your virology questions and comments to [email protected]

Daniel Griffin provides his weekly clinical report on COVID-19, including analysis of vitamin D levels in patients, information on Moderna and Pfizer vaccines, distribution plans suggested by ACIP, and more.

Hosts: Daniel Griffin and Vincent Racaniello

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Download TWiV 689 (22 MB .mp3, 37 min)
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Intro music is by Ronald Jenkees

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On this episode, UK grants EUA for Pfizer vaccine, advice for CDC on who to immunize first, news from Das Coronavirus, SARS-CoV-2 protease regulates innate responses, and viral mRNAs are not an indication of viral replication.

Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker

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Download TWiV 688 (66 MB .mp3, 110 min)
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Weekly Picks 1:34:45

BriannePedromics
KathyGlobal map at Mars opposition
RichJaneway’s Immunobiology
VincentJanet Iwasa’s Animation Lab

Listener Pick

Cheryl – BioRender.com holiday card templates

Intro music is by Ronald Jenkees

Send your virology questions and comments to [email protected]

Peter Hotez joins TWiV to discuss the COVID-19 pandemic, including why it went out of control in the US, the hijacking of public health practices by anti-science extremist groups, prospects for control, and whether we will be prepared for the next one.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Brianne Barker

Guest: Peter Hotez

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Download TWiV 687 (83 MB .mp3, 138 min)
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Weekly Science Picks 2:06:06

DicksonThe World’s First Energy-Positive Hotel to Open in Norway
BrianneThe Food Lab: Better Home Cooking Through Science
AlanACIP’s ethical principles for COVID-19 vaccine allocation
RichThe Mandolorian
VincentT. rex and the Crater of Doom by Walter Alvarez

Intro music is by Ronald Jenkees

Send your virology questions and comments to [email protected]

Daniel Griffin provides his weekly clinical report on COVID-19, including new post-exposure guidelines from CDC, clinical trials of Remdesivir and convalescent plasma, FDA EUA for baricitinib and Regeneron’s monoclonal antibody and more.

Hosts: Daniel Griffin and Vincent Racaniello

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Download TWiV 686 (21 MB .mp3, 35 min)
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Intro music is by Ronald Jenkees

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The TWiVers analyze efficacy of the AstraZeneca/Oxford adenovirus vectored vaccine, SARS-CoV-2 did not infect miners who became ill 8 years ago after cleaning bat guano from a cave in Yunnan Province, and induction of antigen-specific germinal center responses and production of neutralizing antibody by SARS-CoV-2 mRNA vaccine but not purified protein.

Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker

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Download TWiV 685 (66 MB .mp3, 110 min)
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Weekly Picks 1:40:35

BrianneTypes of Scientists Coloring Book
KathySouth Pole video
RichSteve Jobs by Walter Isaacson
VincentScreenology (I interviewed Deb Sklut here)

Listener Pick

MonaAd5 vector and podcast with ImmunityBio founder

Intro music is by Ronald Jenkees

Send your virology questions and comments to [email protected]

Daniel Griffin provides a clinical report on COVID-19, and Shane Crotty explains a study of antibodies, B cells and T cells in patients which suggests that immunological memory to SARS-CoV-2 might be long-lived.

Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Brianne Barker

Guests: Daniel Griffin and Shane Crotty

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Download TWiV 684 (110 MB .mp3, 184 min)
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Weekly Science Picks 2:44:51

DicksonBenoit Mandlebrot’s 96 birthday
Brianne#BlackinImmunoWeek
RichGoISSWatch ISS Tracking; Spot The Station (NASA)
VincentMicrobes Rule

Listener Pick

AgdaSandwalk

Intro music is by Ronald Jenkees

Send your virology questions and comments to [email protected]