TWiV 94: XMRV with Dr. Ila Singh

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Ila Singh

Vincent, Alan, and Rich speak with Ila Singh about the new human retrovirus XMRV, and how her laboratory is studying its association with prostate cancer and chronic fatigue syndrome.

Click the arrow above to play, or right-click to download TWiV #94 (56 MB .mp3, 77 minutes)

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Weekly Science Picks

Alan – The new Federal Register site (see also regulations.gov)
Rich – The Florida Museum of Nautural History Butterfly Rainforest
Vincent – JoVE, the Journal of Visualized Experiments

Send your virology questions and comments to [email protected].

TWiV 93: Our infectious inbox

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich answer listener questions about lab procedures, prokaryotes, endogenous retroviruses, the iPad and teaching, prions, mimivirus, splitting water with viruses, and the polio outbreak in Tajikistan.

Click the arrow above to play, or right-click to download TWiV #93 (76 MB .mp3, 105 minutes)

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Weekly Science Picks

Alan – Southern Fried Science
Rich – Tree of Life web project
Vincent – Dickson Despommier at Big Think

Send your virology questions and comments to [email protected].

TWiV 92: Live at ASV in Bozeman

Hosts: Vincent Racaniello, Rich Condit, Karla Kirkegaard, and Marilyn Roosinck

Vincent, Rich, Karla, and Marilyn recorded TWiV at the 29th Annual Meeting of the American Society for Virology in Bozeman, where they discussed plant viruses and how they make plants resistant to adverse conditions, and identification of dominant negative drug targets.

Click the arrow above to play, or right-click to download TWiV #92 (42 MB .mp3, 57 minutes)

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Weekly Science Picks

Marilyn – Viruses in the faecal microbiota of monozygotic twins and their mothers (Nature)
Rich – The Known Universe by the American Museum of Natural History
Vincent – The Red Queen by Matt Ridley (thanks, Jesper!)

Send your virology questions and comments to [email protected].

TWiV 91: You’re an ERVous wreck

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Welkin Johnson

Vincent, Dickson, Alan, Rich and Welkin discuss the nature, origin, and evolution of endogenous retroviruses (ERVs), and the recent finding of endogenous filovirus genomes in mammals.

Click the arrow above to play, or right-click to download TWiV #91 (64 MB .mp3, 89 minutes)

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Weekly Science Picks

Welkin – Advice for a Young Investigator by Santiago Ramon y Cajal
Rich – How microbes define and defend us
Dickson – H1N1 virus lacks 1918 virus killer protein
Alan – The Xtal Set Society
Vincent – Antibodies and the quest for an AIDS vaccine

Send your virology questions and comments to [email protected].

TWiV 90: Guano happens

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Eric F. Donaldson

Vincent, Alan, Rich and Eric discuss identification of viruses in Northeastern American bats, vaccinia virus infection after sexual contact with a military vaccinee, and identification of a new flavivirus from an Old World bat in Bangladesh.

Click the arrow above to play, or right-click to download TWiV #90 (64 MB .mp3, 89 minutes)

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Weekly Science Picks

Eric – Year of Darwin by Sean Carroll
Rich – March of the Penguins
Alan – Standing-height desks
Vincent – DengueWatch (thanks Richard!)

Send your virology questions and comments to [email protected].

TWiV 89: Where do viruses vacation?

Hosts: Vincent Racaniello and Alan Dove

Vincent and Alan review recent findings on the association of the retrovirus XMRV with ME/CFS, reassortment of 2009 pandemic H1N1 influenza virus in swine, and where influenza viruses travel in the off-season.

Click the arrow above to play, or right-click to download TWiV #89 (56 MB .mp3, 78 minutes)

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Weekly Science Picks

Alan – Tree of Life graphic
Vincent – TEDx Oil Spill

Send your virology questions and comments to [email protected].

TWiV 88: A bug fix, an AIDS treatment, and an undead retrovirus

Hosts: Vincent Racaniello, Alan Dove, and Marc Pelletier

Vincent, Alan, and Marc discuss using a virus for beetle control, RNA based gene therapy for AIDS, and reconstitution of a endogenous human retrovirus.

This episode is sponsored by Data Robotics Inc.

Click the arrow above to play, or right-click to download TWiV #88 (68 MB .mp3, 91 minutes)

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Weekly Science Picks

Marc – Apple iPad as a tool for writing, with Papers, Pages, and GoodReader
Alan – The Bacterium and the Bacteriophage
Vincent – Naturally Obsessed (thanks, Sharon!)

Send your virology questions and comments to [email protected].

TWiV 87: A PHIREside chat with Professor Graham Hatfull

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Graham Hatfull

Vincent, Alan, and Rich hear from Professor Graham Hatfull how students in the Phage Hunters Integrating Research and Education (PHIRE) program learn about scientific inquiry by doing research on bacteriophages.

This episode is sponsored by Data Robotics Inc.

Click the arrow above to play, or right-click to download TWiV #87 (62 MB .mp3, 86 minutes)

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Links for this episode:

Weekly Science Picks

Rich – CDC Public Health Image Library
Alan – Great Microbiologists – A Lego Movie
Vincent – March of the Microbes by John L. Ingraham
Graham – Coral Reefs in the Microbial Seas by Forest Rohwer

Send your virology questions and comments to [email protected].

TWiV 86: Dark matter with Dr. Eric Delwart

Hosts: Vincent Racaniello, Rich Condit, and Eric Delwart

Vincent and Rich travel to the Blood Systems Research Institute in San Francisco to speak with Eric Delwart about his work on virus discovery.

This episode is sponsored by Data Robotics Inc.

Click the arrow above to play, or right-click to download TWiV #86 (59 MB .mp3, 81 minutes)

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Links for this episode:

Weekly Science Picks

Rich – Google Crisis Response – Gulf of Mexico Oil Spill
Vincent – HHMI resources for teachers and students (thanks, Jim!)
Eric – Vaccine by Arthur Allen

Send your virology questions and comments to [email protected].

TWiV 85: Hepatitis C virus with Professor Michael Gale

Hosts: Vincent Racaniello and Michael Gale

Vincent and Michael Gale discuss the origin, pathogenesis, prevention, of hepatitis C virus, and how it evades innate immune responses.

This episode is sponsored by Data Robotics Inc.

Click the arrow above to play, or right-click to download TWiV #85 (40 MB .mp3, 56 minutes)

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Links for this episode:

  • The Gale Laboratory at the University of Washington
  • Incredible view from the Gale laboratory (jpg)
  • Evasion and disruption of innate immune signalling by hepatitis C and West Nile viruses (review)
  • New potent HCV inhibitor
  • HCV virion and genome structures at ViralZone
  • Episode transcript (pdf)

Send your virology questions and comments to [email protected].

The Hosts of TWiV

Vincent Racaniello, Ph.D.


Brianne Barker, Ph.D.


Rich Condit, Ph.D.


Alan Dove, Ph.D.


Daniel Griffin, M.D.,
Ph.D., CTropMed CTH


Angela Mingarelli, DVM


Jolene Ramsey, Ph.D.


Kathy Spindler, Ph.D.


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