TWiV 104: The colony-collapse blues

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Rich Condit

The entire TWiV family reviews the latest ideas about colony collapse disorder of honeybees, and resurgence of monkeypox in Africa.

Click the arrow above to play, or right-click to download TWiV #104 (70 MB .mp3, 97 minutes)

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Links for this episode:

Weekly Science Picks

Dickson – Four Fish by Paul Greenberg
Alan – Nikon Small World contest, 2010 winners
Rich – Encyclopedia of Life
Vincent – First all-digital science textbook will be free (thanks, @windsurfer)

Send your virology questions and comments to [email protected].

TWiV 103: Shots with LJ Tan

Hosts: Vincent Racaniello, Alan Dove, and LJ Tan

Vincent and Alan discuss influenza vaccines with LJ Tan of the American Medical Association.

Click the arrow above to play, or right-click to download TWiV #103 (56 MB .mp3, 77 minutes)

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Links for this episode:

Weekly Science Picks

Alan – BioGene, an iApp
Vincent – The Vertical Farm by Dickson Despommier

Send your virology questions and comments to [email protected].

TWiV 102: Catch me if you can in Munich

Hosts: Vincent Racaniello, Andrew Baker, Karl-Klaus Conzelmann, Peter Palese, and Katharina Eisenächer

A conversation about the RNA sensor RIG-I, adenovirus gene therapy, a universal influenza vaccine, and rabies virus, recorded in Munich, Germany at the SFB455 symposium ‘Viral offense and immune defense’.



Click the arrow above to play, or right-click to download TWiV #102 (67 MB .mp3, 95 minutes)

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Links for this episode:

Weekly Science Picks

Katharina – Deutsches Museum
Vincent – HHMI holiday lectures on science (thanks Judi!)

Send your virology questions and comments to [email protected].

TWiV 101: Sizing up adenovirus

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Dickson Despommier, and Hamish Young

Vincent, Alan, Rich, Dickson, and Hamish review the three-dimensional structure of adenovirus, and the role of adenovirus type 36 in obesity.

Click the arrow above to play, or right-click to download TWiV #101 (55 MB .mp3, 76 minutes)

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Links for this episode:

Weekly Science Picks

Alan – National Geographic’s Best Environmental Photographs of 2010
Rich – Richard Feynman lecture: The pleasure of finding things out
Vincent – Summary of the First International XMRV Workshop (pdf)

Send your virology questions and comments to [email protected].

TWiV 100: TWiV catches a big fish

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and David Baltimore

Vincent, Alan, and Rich celebrate the 100th episode of TWiV by talking about viruses with Nobel Laureate David Baltimore.

Click the arrow above to play, or right-click to download TWiV #100 (68 MB .mp3, 94 minutes)

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Links for this episode:

Weekly Science Picks

Alan – TimeTree
Rich – The neurons that shaped civilization
Vincent – Ahead of the Curve: David Baltimore’s Life in Science by Shane Crotty

Send your virology questions and comments to [email protected].

TWiV 99: ICAAC Boston 2010

Host: Vincent Racaniello

On episode 99 of the podcast This Week in Virology, Vincent tours the 50th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) in Boston, speaking with exhibitors and visitors, including Professors Derek Smith, Michael Schmidt, Frederick Hayden, and Myra McClure.

Many thanks to Chris Condayan and Ray Ortega of the American Society for Microbiology for recording and editing this episode.



Click the arrow above to play, or right-click to download TWiV #99 (45 MB .mp3, 62 minutes)

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Send your virology questions and comments to [email protected].

TWiV 98: Murine musings, electric shirts, and rabid pathologists

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich review the finding of murine leukemia virus-related sequences in the blood of CFS patients and healthy donors, laboratory inventories for wild poliovirus containment, weaving high-performance viral batteries into fabric for the military, and a case of human rabies in Indiana.

Click the arrow above to play, or right-click to download TWiV #98 (58 MB .mp3, 80 minutes)

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Links for this episode:

Weekly Science Picks

Alan – NCBI ROFL
Rich – The Great Bridge by David McCullough
Vincent – Dr. Rous’ Prize-Winning Chicken

Send your virology questions and comments to [email protected].

TWiV 97: California virology

Hosts: Vincent Racaniello, Peter Sarnow, and Bert Semler

During a trip to California, Vincent visited Peter Sarnow and Bert Semler and spoke with them about their work on internal ribosome entry, and the requirement for a cellular microRNA for hepatitis C virus replication.

Click the arrow above to play, or right-click to download TWiV #97 (66 MB .mp3, 91 minutes)

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Links for this episode:

  • Eukaryotic mRNAs that might contain an IRES (PNAS)
  • Modulation of HCV RNA abundance by a liver-specific microRNA (Science)
  • Viral small RNAs (PLoS Pathogens)
  • Bridging IRES elements to the translation apparatus (Biochim Biophys Acta)
  • A nucleo-cytoplasmic SR protein functions in viral IRES mediated translation (EMBO J)
  • Nuclear vs cytoplasmic routes to IRES mediated translation (Trends in Microbiology)
  • Letter read on TWiV 97

Send your virology questions and comments to [email protected].

TWiV 96: Making viral DNA

Hosts: Vincent Racaniello, Dickson Despommier, and Rich Condit

Vincent, Dickson, and Rich continue Virology 101 with a discussion of how viruses with DNA genomes replicate their genetic information.



Click the arrow above to play, or right-click to download TWiV #96 (65 MB .mp3, 90 minutes)

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Links for this episode:

Weekly Science Picks

Rich – Breast milk sugars give infants a protective coat (NY Times and PNAS article)
 Vincent – The Great American University by Jonathan R. Cole

Send your virology questions and comments to [email protected].

TWiV 95: Does a virus shift in the woods?

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Rich Condit

Vincent, Dickson, Alan, and Rich consider the end of the influenza H1N1 pandemic, dengue in Florida, vaccinia virus infection in Brazilian monkeys, and viruses in the faecal microbiota.

Click the arrow above to play, or right-click to download TWiV #95 (68 MB .mp3, 94 minutes)

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Links for this episode:

Weekly Science Picks

Alan – Families Fighting Flu
Rich – Food, Inc.
Dickson –  Fuel
Vincent – MIT Open Courseware
Michael –  Waiting for Superman and Can Science Feed the World? (Nature)

Send your virology questions and comments to [email protected].

The Hosts of TWiV

Vincent Racaniello, Ph.D.


Brianne Barker, Ph.D.


Rich Condit, Ph.D.


Alan Dove, Ph.D.


Daniel Griffin, M.D.,
Ph.D., CTropMed CTH


Angela Mingarelli, DVM


Jolene Ramsey, Ph.D.


Kathy Spindler, Ph.D.


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