Hosts: Vincent Racaniello, Alan DoveRich Condit, and Ila Singh

Vincent, Alan, and Rich speak with Ila Singh about the new human retrovirus XMRV, and how her laboratory is studying its association with prostate cancer and chronic fatigue syndrome.

Click the arrow above to play, or right-click to download TWiV #94 (56 MB .mp3, 77 minutes)

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Weekly Science Picks

Alan – The new Federal Register site (see also regulations.gov)
Rich –
The Florida Museum of Nautural History Butterfly Rainforest
Vincent – JoVE, the Journal of Visualized Experiments

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Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich answer listener questions about lab procedures, prokaryotes, endogenous retroviruses, the iPad and teaching, prions, mimivirus, splitting water with viruses, and the polio outbreak in Tajikistan.

Click the arrow above to play, or right-click to download TWiV #93 (76 MB .mp3, 105 minutes)

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Alan – Southern Fried Science
Rich –
Tree of Life web project
Vincent – Dickson Despommier at Big Think

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Hosts: Vincent Racaniello, Rich Condit, Karla Kirkegaard, and Marilyn Roosinck

Vincent, Rich, Karla, and Marilyn recorded TWiV at the 29th Annual Meeting of the American Society for Virology in Bozeman, where they discussed plant viruses and how they make plants resistant to adverse conditions, and identification of dominant negative drug targets.

Click the arrow above to play, or right-click to download TWiV #92 (42 MB .mp3, 57 minutes)

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Marilyn – Viruses in the faecal microbiota of monozygotic twins and their mothers (Nature)
Rich –
The Known Universe by the American Museum of Natural History
Vincent – The Red Queen by Matt Ridley (thanks, Jesper!)

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Hosts: Vincent Racaniello, Dickson DespommierAlan Dove, Rich Condit, and Welkin Johnson

Vincent, Dickson, Alan, Rich and Welkin discuss the nature, origin, and evolution of endogenous retroviruses (ERVs), and the recent finding of endogenous filovirus genomes in mammals.

Click the arrow above to play, or right-click to download TWiV #91 (64 MB .mp3, 89 minutes)

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Welkin – Advice for a Young Investigator by Santiago Ramon y Cajal
Rich –
How microbes define and defend us
Dickson – H1N1 virus lacks 1918 virus killer protein
Alan –
The Xtal Set Society
Vincent – Antibodies and the quest for an AIDS vaccine

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Hosts: Vincent RacanielloAlan Dove, Rich Condit, and Eric F. Donaldson

Vincent, Alan, Rich and Eric discuss identification of viruses in Northeastern American bats, vaccinia virus infection after sexual contact with a military vaccinee, and identification of a new flavivirus from an Old World bat in Bangladesh.

Click the arrow above to play, or right-click to download TWiV #90 (64 MB .mp3, 89 minutes)

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Eric – Year of Darwin by Sean Carroll
Rich –
March of the Penguins
Alan –
Standing-height desks
Vincent – DengueWatch (thanks Richard!)

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Hosts: Vincent Racaniello and Alan Dove

Vincent and Alan review recent findings on the association of the retrovirus XMRV with ME/CFS, reassortment of 2009 pandemic H1N1 influenza virus in swine, and where influenza viruses travel in the off-season.

Click the arrow above to play, or right-click to download TWiV #89 (56 MB .mp3, 78 minutes)

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AlanTree of Life graphic
Vincent
TEDx Oil Spill

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Hosts: Vincent Racaniello, Alan Dove, and Marc Pelletier

Vincent, Alan, and Marc discuss using a virus for beetle control, RNA based gene therapy for AIDS, and reconstitution of a endogenous human retrovirus.

This episode is sponsored by Data Robotics Inc.

Click the arrow above to play, or right-click to download TWiV #88 (68 MB .mp3, 91 minutes)

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Marc Apple iPad as a tool for writing, with Papers, Pages, and GoodReader
AlanThe Bacterium and the Bacteriophage
Vincent
Naturally Obsessed (thanks, Sharon!)

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Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Graham Hatfull

Vincent, Alan, and Rich hear from Professor Graham Hatfull how students in the Phage Hunters Integrating Research and Education (PHIRE) program learn about scientific inquiry by doing research on bacteriophages.

This episode is sponsored by Data Robotics Inc.

Click the arrow above to play, or right-click to download TWiV #87 (62 MB .mp3, 86 minutes)

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Rich CDC Public Health Image Library
AlanGreat Microbiologists – A Lego Movie
Vincent
March of the Microbes by John L. Ingraham
GrahamCoral Reefs in the Microbial Seas by Forest Rohwer

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Hosts: Vincent Racaniello, Rich Condit, and Eric Delwart

Vincent and Rich travel to the Blood Systems Research Institute in San Francisco to speak with Eric Delwart about his work on virus discovery.

This episode is sponsored by Data Robotics Inc.

Click the arrow above to play, or right-click to download TWiV #86 (59 MB .mp3, 81 minutes)

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Rich – Google Crisis Response – Gulf of Mexico Oil Spill
Vincent
HHMI resources for teachers and students (thanks, Jim!)
EricVaccine by Arthur Allen

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Hosts: Vincent Racaniello and Michael Gale

Vincent and Michael Gale discuss the origin, pathogenesis, prevention, of hepatitis C virus, and how it evades innate immune responses.

This episode is sponsored by Data Robotics Inc.

Click the arrow above to play, or right-click to download TWiV #85 (40 MB .mp3, 56 minutes)

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Links for this episode:

  • The Gale Laboratory at the University of Washington
  • Incredible view from the Gale laboratory (jpg)
  • Evasion and disruption of innate immune signalling by hepatitis C and West Nile viruses (review)
  • New potent HCV inhibitor
  • HCV virion and genome structures at ViralZone
  • Episode transcript (pdf)

Send your virology questions and comments to twiv@microbe.tv.