Tag: zoonosis

Uncategorized

TWiEVO 69: Swimming in SARS-CoV-2 sequences

June 30, 2021
Tagged as: coronavirus, COVID-19, evolution, genome sequence, Rhinolophus bats, SARS-CoV-2, Sequence Read Archive, viral, virology, virus, viruses, zoonosis

Nels and Vincent discuss the identification of novel bat coronaviruses that shed light on the evolution of SARS-CoV-2, dating the first cases of COVID-19 to mid-November 2019, and recovery of deleted genome sequences from early in the Wuhan outbreak.

Episode

TWiEVO 65: Variants in the mist

February 25, 2021
Tagged as: adaptive changes, COVID-19, evolution, evolutionary sweep, natural selection, positive selection, spillover, variant of concern, zoonosis

Nels and Vincent review evidence that a single amino acid change in the SARS-CoV-2 spike protein has driven adaptation to humans, followed by an update on the status of variants of concern.

Episode

TWiEVO 58: Not all coronaviruses ACE2 the test

August 13, 2020
Tagged as: ACE2, evolution, Rhinolophus bats, Sarbecovirus, SARS-CoV-2, spillover, viral, virology, virus, viruses, zoonosis

Simon and Heather join TWiEVO to discuss their analysis of the evolutionary history of ACE2 usage by coronaviruses in the Sarbecovirus genus.

Episode

TWiEVO 52: Virus evolution by land and by sea and by CoV

February 26, 2020
Tagged as: ACE2, bat, coronavirus, CoV, evolution, pangolin, positive selection, receptor binding domain, SARS-CoV-2, spike glycoprotein, virus, viruses, zoonosis

Nels and Vincent examine SARS-CoV-2 from an evolutionary viewpoint, examining what the spike glycoprotein sequence informs us about the origin of the virus.

Tag: zoonosis

TWiEVO 69: Swimming in SARS-CoV-2 sequences

TWiEVO 65: Variants in the mist

TWiEVO 58: Not all coronaviruses ACE2 the test

TWiEVO 52: Virus evolution by land and by sea and by CoV

Search

Contribute