Nels and Vincent review evidence that a single amino acid change in the SARS-CoV-2 spike protein has driven adaptation to humans, followed by an update on the status of variants of concern.
TWiEVO 58: Not all coronaviruses ACE2 the test
- August 13, 2020
- Tagged as: ACE2, evolution, Rhinolophus bats, Sarbecovirus, SARS-CoV-2, spillover, viral, virology, virus, viruses, zoonosis
Simon and Heather join TWiEVO to discuss their analysis of the evolutionary history of ACE2 usage by coronaviruses in the Sarbecovirus genus.