Nels and Vincent review a study of the dogs of Chernobyl which reveals that genetically distinct populations with different amounts of western breed contributions to their genomes, the first step in assessing the effects of exposure to long-term ionizing radiation.
Nathan joins Nels and Vincent to discuss his approach to understanding how species adopt novel traits to overcome challenges, and its application to identifying coding and noncoding sequence changes that underlie mammalian hairlessness. Hosts: Nels…
Nels and Vincent discuss how evolution of changes in stop codon assignment might occur, and a novel mechanism for altering the meaning of translation stop codons discovered in a trypanosomatid with the apropos name, Blastocrithidia nonstop.
Nels and Vincent discuss the use of genome sequence data for over 4,000 domestic, semi-feral, and wild canids to understand the genetic drivers of canine behavior.
Nels and Vincent review the use of ancient DNA to identify loci that may have been under selection during the Black Death by studying populations before, during, and after the pandemic.
Florian Maderspacher from Current Biology joins Nels and Vincent to discuss a special issue of the journal on birds.
Nels and Vincent consider evidence that a single amino acid change in the TKTL1 gene might have led to greater neurogenesis in the frontal cortex of modern humans compared with Neanderthals.
Nels and Vincent discuss how duplication of a gene encoding a transcription factor led to evolution of a novel cell type in the slime mold Dictyostelium.
Louise Moncla joins Nels and Vincent to review her use of genomics to understand emergence, evolution, and transmission of respiratory viruses including influenza virus H5N1, mumps virus, and SARS-CoV-2.
Nels and Vincent discuss an analysis of the drivers of evolution of SARS-CoV-2 during chronic infections, indicating that a tradeoff exists between antibody evasion and fitness.