Nels and Vincent discuss the observation that cells on a boundary of a solid tumor have higher growth rates compared to those in the center and how to model this difference using genome sequencing data.
TWiEVO 69: Swimming in SARS-CoV-2 sequences
- June 30, 2021
- Tagged as: coronavirus, COVID-19, evolution, genome sequence, Rhinolophus bats, SARS-CoV-2, Sequence Read Archive, viral, virology, virus, viruses, zoonosis
Nels and Vincent discuss the identification of novel bat coronaviruses that shed light on the evolution of SARS-CoV-2, dating the first cases of COVID-19 to mid-November 2019, and recovery of deleted genome sequences from early in the Wuhan outbreak.
TWiEVO 54: Rough drafts of SARS-CoV-2 science
- April 25, 2020
- Tagged as: coronavirus, CoV, COVID-19, evolution, furin cleavage site, genome sequence, natural selection, SARS-CoV-2, viral, virology, virus
Nels and Vincent continue their discussion of SARS-CoV-2 from an evolutionary viewpoint, including function of the furin cleavage site, whether Vervet cells are an informative system, another bat isolate, and a nomenclature to assist genomic epidemiology.
Nels visits Vincent in the MicrobeTV studio in New York and talks about how key genes of the Homo sapiens innate immune response were acquired from Neanderthals.