Immune discusses how cancer cells swap mitochondria with T cells and then digs in for a discussion of an unusual checkpoint blockade that failed for cancer but could be repurposed for autoimmune inflammation. Hosts: Vincent Racaniello,…
Immune Booster #15 Vaccine ground rules with Shane Crotty
- August 12, 2025
- Tagged as: antibodies, B cells, immune, immunity, immunology, pandemic, SARS-CoV2, vaccination
Cindy talks with Shane Crotty about his teenage days driving 3 ½ hours every weekend to have his first research experience in marine biology, how that eventually led to studying how vaccines work and how…
Immune 94: The nose knows
- July 29, 2025
- Tagged as: complement, granzyme, IgA, immune, immunity, immunology, nasal immunity, nose, respiratory
The Immune team goes up the nose to discuss cytotoxic T cells activating complement through secretion of granzyme K to drive inflammatory nasal polyps and how IgA-producing B cells are made in the nose. Hosts: Vincent…
Immune Booster #14: In the eye of immune responses with Darren Lee
- July 8, 2025
- Tagged as: autoimmune, eye, eye immunity, immune, immune regulation, immunity, inflammation, uveitis
From the 2024 Society for Leukocyte Biology meeting, Cindy and Brianne talk with Darren Lee to discuss his career, how he got interested in immunology of the eye, and how his team visualizes immune responses…
Immune 93: Macrophages managing memory B cells
- June 24, 2025
- Tagged as: immune, immunity, immunology, lymph node, memory B cell, T cell, vaccine, virus infection
Vincent and Cindy discuss differences between MPox-specific T cell responses following infection and vaccination, and lymph node macrophage control of memory B cell localization and trafficking that might be important for choosing which arm to…
Immune Booster #13: Microbiome and regulation of gut inflammation with Justin Wilson
- June 10, 2025
- Tagged as: cancer, immune, immunity, inflammatory bowel disease, innate immunity, microbiome, microbiota, NLRP
From the 2024 Society for Leukocyte Biology meeting, Cindy and Brianne sit down with Justin Wilson to talk about how he got into research and his more recent studies on innate immune sensors and the…
Immune 92: Gut symbiont breaks antibody
- May 27, 2025
- Tagged as: IgA, immune, immunity, immunology, maternal antibody, microcephaly, neuroimmunology, phagocyte, Zika virus
Steph talks about identification of gut bacteria that can digest protective mucosal antibodies and Vincent covers a new paper on Zika virus that implicates fetal phagocytes in brain invasion, which may provide insight into the…
Immune Booster #12: Innate immunity to Archaea with Holger Heine
- May 13, 2025
- Tagged as: archaea, immune, immunity, inflammation, innate receptor signaling, LPS, Toll-like receptors
From the 2024 Society for Leukocyte Biology meeting, Immune talks with Holger Heine about the discovery of immune recognition of bacterial lipopolysaccharide and innate immunity to organisms within the kingdom Archaea. Hosts: Cindy Leifer and Brianne…
Immune 91: People, parasites, plagues, and podcasts
- April 29, 2025
- Tagged as: CD8 T cells, immune, immunity, immunology, interferon, malaria, parasites, podcasting
Immune talks with David Peterson and Kim Klonowski from the University of Georgia about their careers, their People, parasites, and plagues podcast, placental malaria immunity, and and how interferons in the thymus affect T cell…
Immune Booster #11: Immunity to Fungi with Amy Hise
- April 9, 2025
- Tagged as: candida, fungus, immune, immunity, microbiome
From the 2024 Society for Leukocyte Biology meeting, Immune talks with Amy Hise about her career in science, her current research using mouse models for investigating fungal immunity and navigating the challenges of being a…
