Daniel Griffin provides a clinical report on COVID-19, then we discuss decline of virus-specific bone marrow B cells within a year after influenza vaccination, the push to release SARS-CoV-2 vaccines before completion of phase 3 trials, and absence of evidence for infectious virus in aerosols.
Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Kathy Spindler, and Brianne Barker
Guest: Daniel Griffin
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Download TWiV 660 (95 MB .mp3, 159 min)
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Links for this episode
- Convalescent plasma RCT (medRxiv) 18:15
- Multicenter RCTs on corticosteroids for COVID-19 (JAMA) 19:24
- Decline of influenza B cells a year after vaccine (Science) 54:55
- Be ready to distribute vaccines 1 Nov (WPRI and NYTimes) 1:23:17
- EUA during COVID-19: lessons (JAMA) 1:25:15
- Not evidence for aerosol transmission (one and two) 1:43:16
- Letters read on TWiV 660 35:43, 48:09, 1:50:13
- Timestamps by Jolene. Thanks!
Intro music is by Ronald Jenkees
Send your virology questions and comments to twiv@microbe.tv
Phase 3 trials can not be rushed any more than nine women can make a baby in one month.
Please discuss the measles paradigm a bit further to clarify how from observed factors such as R it would be clear that aerosol type transmission is unlikely in most circumstances. love the show for its explanation capability and minimum of opinion only discussion
Sam (@ 2:08:36) is SPOT ON! Trying to play nice because his followers whine doesn’t work, Trump politicized everything and so calling him and his supporters out is perfectly acceptable and required if we are to improve the situation and progress.
Could you have Dr. Griffin give the contact information again for the testinator program from ProHealth? It is supposed to be Dr. Bonnie Simmons? That is, bsimmons@prothealth.com?
I searched and could not find the contact information.
Thank you.
Just after 15:40 in the ‘cast BSimmons@prohealthcare.com Notice, only one “t” in prohealthcare 😉
Dr Griffin mentioned “readiness cohorts” for vaccine testing early in TWIV 660. Is there a place to sign up to be on such a panel of potential vaccine trial recipients? Thanks for your informative podcast.