TWiV 181: ORFan poxviruses and nIRFing prions

Cotia virus by Maria Luiza MedagliaHosts: Vincent Racaniello, Rich Condit, and Kathy Spindler

Vincent, Rich, and Kathy discuss Cotia virus, a new poxvirus, Orf virus infections associated with handling goats and lamb, and the innate immune response to prions.

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Weekly Science Picks

Kathy – Astronomy Picture of the Day (especially this and this)
Rich – Tom Lehrer Element Song (YouTube)
Vincent – Albert B. Sabin Archives

Listener Pick of the Week

Spencer – Netter’s Infectious Diseases by Elaine C. Jong and Dennis L. Stevens
Richard – Germs, Genes & Civilization by David P. Clark

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TWiV 180: Throwing IFIT at flu and holding a miR to HCV

mir122Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich review association of an interferon-induced protein with severe influenza, and stabilization of HCV RNA by a microRNA.

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Weekly Science Picks

Alan – Micro Empire (Vimeo)
Rich – Census of marine life
Vincent – Pinterest

Listener Pick of the Week

Mark – The Secret Life of Plankton (YouTube)

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TWiV 179: Was ist ein Virus?

hornworm parasitized by waspHosts: Vincent Racaniello, Alan Dove, Rich Condit, and Gertrud Radu

Gertrud joins the TWiVoners to review how dengue virus infection of mosquitoes alters blood feeding behavior, and gene therapy as practiced by parasitoid wasps.

Click the arrow above to play, or right-click to download TWiV 179 (76 MB .mp3, 105 minutes).

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Weekly Science Picks

Gertrud – Bat on a plane! (MMWR)
Alan – The Rings of Earth (YouTube)
Rich – Giant Magellan telescope
Vincent – Hepatitis C new drug pipeline

Listener Pick of the Week

Ricardo – Evolution: The Natural History of Animal Skeletons
Peter – Self-assembly line (YouTube)

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TWiV 178: T-Sharp on how tequila mosquito

Tyler SharpHosts: Vincent Racaniello, Alan Dove, Rich Condit, and Tyler Sharp

The TWiValians meet up with Tyler Sharp for a discussion on the Epidemic Intelligence Service and controlling dengue.

Click the arrow above to play, or right-click to download TWiV 178 (72 MB .mp3, 99 minutes).

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Weekly Science Picks

Tyler – Co-infection with dengue and Leptospira (Emerging Inf Dis)
Alan – The Winged Scourge (YouTube)
Rich – Deepsea Challenge
Vincent – Why did a US advisory board reverse its stance? (Ed Yong)

Listener Pick of the Week

Sasha – Microfluidic Future
Adam – The Conversation
Jim –  ENIAC Programmers Project

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TWiV 177: Live in Dublin

Hosts: Vincent Racaniello, Connor Bamford, Wendy Barclay, Richard Elliott, and Ron Fouchier

A discussion of avian influenza H5N1 transmission experiments in ferrets and novel bunyaviruses at the 2012 Spring Conference of the Society for General Microbiology in Dublin, Ireland.



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Weekly Science Picks

Connor – Wellcome Trust Science Writing Prize 2012
Vincent – Thoughts on academic scientists giving media interviews

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twiv dublin 2012

TWiV 176: Ave, magi virorum!

twiv emailHosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich answer listener email about MS, CFS, EBV, B cells, virii, influenza B, scientific papers, and more.

Click the arrow above to play, or right-click to download TWiV 176 (62 MB .mp3, 86 minutes).

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Weekly Science Picks

Rich – Alan Alda’s Flame Challenge (NY Times article, Science editorial)
Alan – ChronoZoom
Vincent – Academic Publishing is Broken by Michael P. Taylor

Listener Pick of the Week

Joel – Fighting a dengue outbreak by Tyler M. Sharp (parts one and two)
Sven-Urban – Fooled by Randomness and The Black Swan by Nassim Nicholas Taleb

Send your virology questions and comments (email or mp3 file) to twiv@microbe.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

TWiV 175: More than one way to skin a virus

microneedleHosts: Vincent Racaniello, Alan Dove, and Matt Frieman

Vincent, Alan, and Matt discuss herpes simplex encephalitis in children with innate immune deficiency, and the local response to microneedle-based influenza skin immunization.

Click the arrow above to play, or right-click to download TWiV 175 (57 MB .mp3, 80 minutes).

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Weekly Science Picks

Matt – Phage and the Origins of Molecular Biology
Alan – Digital Imagine Institute
Vincent – iPad apps Goodreader and Notability

Listener Pick of the Week

Jane –Smoking Ears and Screaming Teeth by Trevor Norton

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TWiV 174: Dog runs and mooing miRs

bucket lab stickersHosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich consider whether pet dogs might transmit human noroviruses, and an RNA virus microRNA that might be involved in oncogenesis.

Click the arrow above to play, or right-click to download TWiV 174 (62 MB .mp3, 86 minutes).

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Weekly Science Picks

Rich – NOAA Buoy Data
Alan – Autism’s False Prophets by Paul Offit
Vincent – Media Mining

Listener Pick of the Week

Mark – How the West fueled the AIDS epidemic
Henry – Regenesis
Rick – Biopunk: DIY scientists hack the software of life by Marcus Wohlsen

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TWiV 173: Going to bat for flu research

Sturnira liliumHosts: Vincent Racaniello, Alan Dove, Rich Condit, Michael Walsh, and Ashlee Bennett

The TWiVites discuss seroevidence for human infection with avian influenza H5N1, and the discovery of a new influenza virus in Guatemalan bats.

Click the arrow above to play, or right-click to download TWiV 173 (85 MB .mp3, 117 minutes).

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Links for this episode:

Weekly Science Picks

Ashlee – AskScience (Reddit)
Michael – HealthMap (iPhone and Android app)
Rich – H5N1 research discussion at ASMBiodefense
Alan – El Yunque National Forest
Vincent – The Journal of Global Health

Listener Pick of the Week

Judi – NSF visualization challenge

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TWiV 172: Two can be as bad as one

tetramer stainingHosts: Vincent Racaniello and Kathy Spindler

Vincent and Kathy discuss how a virus may cause disease distant from its replication site, then review a day in the life of a senior microbiology professor.

Click the arrow above to play, or right-click to download TWiV 172 (74 MB .mp3, 102 minutes).

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Links for this episode:

Weekly Science Picks

Kathy – Science prize for inquiry-based instruction (Alberts editorial, second winner)
Vincent – The long and winding road to a Ph.D.

Listener Pick of the Week

Greg – Correlation

Send your virology questions and comments to twiv@microbe.tv.

The Hosts of TWiV

Vincent Racaniello, Ph.D.


Dickson D.
Despommier, Ph.D.


Alan Dove, Ph.D.


Daniel Griffin, M.D.,
Ph.D., CTropMed CTH


Jolene Ramsey, Ph.D.


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