TWiV 161: Concerto in B

antibodyHosts: Vincent Racaniello, Rich Condit, Alan Dove, and Gabriel Victora

Vincent, Rich, Alan and Gabriel review the production of antibodies by B cells, and how high affinity antibodies are selected in the germinal centers of lymph nodes.

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Weekly Science Picks

Gabriel – Antibody-based protection against HIV (Nature)
Rich – Contact
Alan – Flu shot dystonia (YouTube)
Vincent – Sciflies and RocketHub

Listener Pick of the Week

Neva – Virus and retrovirus
Ayesha – The Life Scientific (BBC)

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TWiV 160: Moore tumor viruses

merkel carcinomaHosts: Vincent Racaniello, Rich Condit, Alan Dove, Dickson Despommier, and Patrick Moore

The TWiV team speaks with Patrick Moore about his discovery, with Yuan Chang, of two human tumor viruses, Kaposi’s sarcoma herpesvirus and Merkel cell polyomavirus.

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Weekly Science Picks

Patrick – The Theory That Would Not Die by Sharon Bertsch McGrayne
Dickson – Foodborne illness acquired in the US (Emerging Inf Dis)
Rich – GATTACA
Alan – Cutting for Stone by Abraham Verghese
Vincent – Boxwave capacitative stylus

Listener Pick of the Week

Neva – 10+1 top science apps
Ricardo – Where’s the outrage?

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TWiV 159: Flu gets the REDD light

ferretHosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich review concern over an influenza H5N1 transmission experiment, and a new host defense protein against RNA viruses.

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Weekly Science Picks

Rich – Livescribe Smartpen
Alan – Royal Society journal archive
 Vincent – Chronic fatigue syndrome and the CDC by Dave Tuller

Listener Pick of the Week

Judi – Top 7 in Microbiology

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TWiV 158: Wolverines go viral

poliovirus + CD155Hosts: Vincent Racaniello, Rich Condit, Alice Telesnitsky, and Kathy Spindler

Vincent and Rich visit the Microbiology and Immunology Department at the University of Michigan Medical School, and speak with Alice and Kathy about their work on HIV genome dimerization, and packaging and pathogenesis of mouse adenovirus.

Model of poliovirus bound to CD155 made by Stefan Taube.

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Weekly Science Picks

Alice – Banvard’s Folly by Paul S. Collins
Kathy – The world at seven billion
Rich – The Princess Bride
 Vincent – Center for the history of microbiology

Listener Pick of the Week

Tim – Dead Ends to Somewhere by Richard L. Ward
Don – Ben Goldacre: Battling bad science (TED)

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TWiV 157: Better innate than never

dendritic cellHosts: Vincent Racaniello, Rich Condit, Alan Dove, Dickson Despommier, Jeremy Luban, and Gabriel Victora

A large TWiV panel remembers Ralph Steinman, and considers a new innate sensor of retroviral capsids.

Photograph of a dendritic cell (green) interacting with T cells (cyan) near a blood vessel by Gabriel Victora.

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Weekly Science Picks

Dickson – Eats, Shoots & Leaves by Lynne Truss
Rich – Battlestar Galactica
Alan – Coleman LED quad lantern
Gabriel – A History of Immunology by Arthur M. Silverstein
Jeremy – Principles of Virology by Flint, Enquist, Racaniello, Skalka
Vincent – Principles of Molecular Virology by AJ Cann

Listener Pick of the Week

David – Carl Sagan’s Pale Blue Dot (YouTube)

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TWiV 156: Armed and targeted killer meta-analysis

jx-594Hosts: Vincent Racaniello, Rich Condit, and Dickson Despommier

Vincent, Rich, and Dickson review a meta-analysis on influenza vaccine, a killer virus in fungi that selects against RNAi, and the use of armed and targeted poxviruses for oncolytic virotherapy.

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Weekly Science Picks

Rich – Google’s self-driving car (story one and two)
Dickson – Wild Russia and Wild China TV series
Vincent – Baculovirus molecular biology by George Rohrmann (free)

Listener Pick of the Week

Jim – Lee Cronin: Making matter come alive (TED)

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TWiV 155: XXII Brazilian National Virology Meeting

sbv_logoenv2011Hosts: Vincent Racaniello, Grant McFadden, Eurico de Arruda Neto, Paulo Eduardo Brandão, Francisco Murilo Zerbini, and Janice Reis Ciacci Zanella

Vincent, Grant, Eurico, Paulo, Francisco and Janice discuss their work on bocavirus, infectious bronchitis virus, begomoviruses, and circoviruses at the Brazilian Virology Society meeting in Atibaia, São Paulo, Brazil.

Click the arrow above to play, or right-click to download TWiV 155 (56 MB .mp3, 93 minutes).

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Weekly Science Picks

Vincent – AAM Colloquium Program
Grant – The Disappearing Spoon by Sam Kean

Listener Pick of the Week

Antonio – 2011 Nobel Laureates Lectures at Lindau

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TWiV 154: Symbiotic safecrackers

mmtvHosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich are very enthusiastic about two studies that show how gut bacteria help viral invaders.

Click the arrow above to play, or right-click to download TWiV 154 (46 MB .mp3, 77 minutes).

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Weekly Science Picks

Alan – SciWriteLabs
Vincent – Take as directed

Listener Pick of the Week

Tony – Introduction to AI online course

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TWiV 153: Rabid reindeer and protective prions

svalbardHosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich review an outbreak of rabies in arctic foxes and reindeer in Norway, and a prion that makes you go antiviral.

Click the arrow above to play, or right-click to download TWiV 153 (55 MB .mp3, 92 minutes).

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Weekly Science Picks

Alan – Amoebas microscope drive 2011
Vincent – WolframAlpha
Rich – Genesis by Ramos David (YouTube)

Listener Pick of the Week

Bill –Virolution by Frank Ryan

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TWiV 152: Viromes in the effluence of society

shinolaHosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich cover the virome of raw sewage, and a baculovirus gene that causes caterpillars to climb to their doom.

Click the arrow above to play, or right-click to download TWiV 152 (50 MB .mp3, 83 minutes).

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Links for this episode:

Weekly Science Picks

Alan – xkcd tribute to Steve Jobs
Vincent – Steve Jobs’ 2005 Stanford commencement address (YouTube)
Rich – 1984 Apple Macintosh commercial (YouTube)

Listener Pick of the Week

David – Your Inner Fish by Neil Shubin

Send your virology questions and comments to twiv@microbe.tv.

The Hosts of TWiV

Vincent Racaniello, Ph.D.


Dickson D.
Despommier, Ph.D.


Alan Dove, Ph.D.


Daniel Griffin, M.D.,
Ph.D., CTropMed CTH


Jolene Ramsey, Ph.D.


CLICK FOR MORE INFO

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