In COVID-19 clinical update #121, Dr. Griffin discusses age as a risk factor for severe disease, updated vaccine boosters for the fall, pediatric infection and antibody seroprevalence in Arkansas over the first year of the COVID-19 pandemic, all-cause maternal mortality in the United States before and during the pandemic, and the effect of 2-week interruption in methotrexate treatment and how it impacts vaccine immunity.

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Intro music is by Ronald Jenkees

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TWiV explains the meaning of vaccine-derived poliovirus found in London sewage, risk of long COVID after infections with Delta or Omicron variants of SARS-CoV-2, and enhancers of innate immune signaling as broad-spectrum antivirals.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler.

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Weekly Picks 1:32:46

Dickson – Count Basie: April in Paris
Kathy – Bird aerodynamics & inertia: lay article, video, Nature
RichNASA Gateway (Thanks Ellis)
AlanPolio Eradication in Nigeria
Vincent The Tyranny of Merit by Michael J. Sandel

Intro music is by Ronald Jenkees

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In COVID-19 clinical update #120, Dr. Griffin discusses outcomes of SARS-CoV-2 reinfection, CDC recommendation for vaccines in young children, neurodevelopment outcomes in infants of mothers testing positive for COVID during pregnancy, efficacy of monoclonal antibodies and antivirals in hamsters, rebound phenomenon after PAXLOVID in high-risk persons, hospitalization for infection after PAXLOVID treatment, and risk of long COVID with different variants.

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Intro music is by Ronald Jenkees

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TWiV provides an update on hepatitis of unknown etiology in children, an experimental nanoparticle vaccine for Epstein-Barr virus, and minimal impact of bamlanivimab therapy on antiviral antibodies induced by vaccination.

Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker

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Weekly Picks 1:41:20

BrianneA Frog So Small, It Could Not Frog
KathyA Grand Night In: The Story of Aardman
RichArchive
Vincent Bandwagoning by Heran Darwin

Intro music is by Ronald Jenkees

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In COVID-19 clinical update #119, Dr. Griffin reviews tixagevimab for infection prevention, ivermectin for outpatient infection treatment, symptom rebound after PAXLOVID treatment, bamlanivimab minimally impacting immune response to vaccination, in-hospital mortality among infection patients, residual viral antigen in patients following infection, usage of Casirvimab/Imdevimab and Remdesivir in infected patients with depleted B-cells, and rheumatic symptoms following infection.

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Download TWiV 910 (29 MB .mp3, 48 min)
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Intro music is by Ronald Jenkees

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From ASM Microbe 2022 in Washington DC, Vincent and Michael speak with science artists Michele Banks and Jane Hartman about their work and their inspiration.

Hosts: Vincent Racaniello and Michael Schmidt

Guests: Michele Banks and Jane Hartman

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Download TWiV 909 (76 MB .mp3, 127 min)
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Intro music is by Ronald Jenkees

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TWiV discusses the situation with monkeypox, risk factors for SARS-CoV-2 infections of cats and dogs, and a lineage-tracing mouse model for studying papillomavirus infections.

Hosts: Vincent Racaniello, Rich Condit, and Brianne Barker

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Download TWiV 907 (76 MB .mp3, 127 min)
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Weekly Picks 1:29:52

BrianneMicrobes Rule! at Liberty Science Center
RichArtemis I update:  Mission diagram, mission in photos, launch dates
Vincent Eco-sustainable 3D printed house – Tecla

Intro music is by Ronald Jenkees

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In COVID-19 clinical update #118, Dr. Griffin discusses management of hair loss after infection, FDA announcements on vaccine schedule and recommendations, Moderna announcement on bivalent booster candidate, association between vaccination and infection during pregnancy, population-level implications of Israel’s booster campaign, PAXLOVID outcomes during recent infection surge, efficacy and safety of Tixagevimab-cilgavimab, diagnostic accuracy of infection by canines, efficacy of colchicine in hospitalized patients, and factors associated with hospital readmission.  

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Download TWiV 908 (29 MB .mp3, 48 min)
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Intro music is by Ronald Jenkees

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TWiV reviews human monkeypox infections, evidence for human Mimivrus infections, and incidence of long COVID in post-vaccine SARS-CoV-2 infections.

Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Brianne Barker

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Download TWiV 906 (76 MB .mp3, 127 min)
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Weekly Picks 1:25:29

DicksonLake Mead water level very low
BrianneTransplantation of a 3D printed ear made out of human cells
Richnderstanding Vaccine Safety and the Roles of the FDA and the CDC and The Facts About Vaccine Safety
Vincent My new favorite backpack

Listener Pick

GregAgainst the Rules

Intro music is by Ronald Jenkees

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In COVID-19 clinical update #117, Dr. Griffin discusses duration of virus shedding, association between pre-exposure to steroids and infection outcome, post-infection subtypes, rehabilitation for post-acute infection, Tixagevimab/Cilgavimab for infection prevention, antibody prophylaxis and vaccination in kidney transplant recipients, remdesivir and bebtelovimab fact sheets for providers, the updated guidelines on treatment with Famotidine, Paxlovid rebound symptom characterizations, antigen test positivity duration, viral dynamics of variants and isolation, association of inflammation in CS fluid, and transmission dynamics in Ghana. 

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Download TWiV 905 (29 MB .mp3, 48 min)
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Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv